PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | evm_27.model.AmTr_v1.0_scaffold00030.186 | ||||||||
Common Name | AMTR_s00030p00231260 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; basal Magnoliophyta; Amborellales; Amborellaceae; Amborella
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Family | E2F/DP | ||||||||
Protein Properties | Length: 430aa MW: 47917.7 Da PI: 5.0006 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 85.4 | 4.3e-27 | 138 | 203 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirw 69 r+++sL+llt+kf++l++++e+g+++ln++a+ L +v ++RRiYDi+NVLe+++liekk kn+irw evm_27.model.AmTr_v1.0_scaffold00030.186 138 RYDSSLGLLTKKFINLIKQAEDGVLDLNKAAEIL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRW 201 6899******************************...99..**************************** PP E2F_TDP 70 kg 71 kg evm_27.model.AmTr_v1.0_scaffold00030.186 202 KG 203 98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 6.3E-29 | 136 | 205 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.0E-17 | 138 | 201 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.0E-34 | 138 | 203 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.9E-24 | 140 | 203 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 2.06E-50 | 214 | 320 | No hit | No description |
SuperFamily | SSF144074 | 2.88E-34 | 215 | 320 | No hit | No description |
Pfam | PF16421 | 5.2E-35 | 219 | 318 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0010090 | Biological Process | trichome morphogenesis | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051302 | Biological Process | regulation of cell division | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005737 | Cellular Component | cytoplasm | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 430 aa Download sequence Send to blast |
MSGGRGLNRV HQPPGPVIHQ PLRRHLPFSS SKPSFANPGD YHQFSEAGKR EESDALVVTS 60 PLKRKYDTEE HEAESSDWAT SQGYAEVVNS PLHTPISIKG KGYSRGKASR YTKSGPPTPI 120 SNAGSPASNT LTPVGTCRYD SSLGLLTKKF INLIKQAEDG VLDLNKAAEI LEVQKRRIYD 180 ITNVLEGIGL IEKKLKNRIR WKGLDVSRPG EVDEDIAVLQ AEVQNLHLEE HRIDEQIREM 240 QKSLRDLSED ENNQKWLYVT EEDIKGLPCF QNETLIAIKA PHGTTLEVPD PDEAVEYPQR 300 RYQILLRSTM GPIDVYLVSQ FKKLEEVNSV ADSPLQPPQS TPDHVVTSSL PTTLETSRRV 360 EMEAEGQDGS QDFVGGFMKL VPSEIDTEAD YWLLSDPPGV SITEIWKADR ASAVHPDDGW 420 ERSTVLWYG* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 1e-23 | 133 | 204 | 1 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00661 | PBM | Transfer from Pp3c1_6880 | Download |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_011627152.1 | 0.0 | transcription factor E2FA | ||||
Refseq | XP_020529414.1 | 0.0 | transcription factor E2FA | ||||
Swissprot | Q9FV71 | 1e-133 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | U5D432 | 0.0 | U5D432_AMBTC; Uncharacterized protein | ||||
STRING | ERN16172 | 0.0 | (Amborella trichopoda) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Representative plant | OGRP1225 | 17 | 49 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G22220.3 | 1e-136 | E2F transcription factor 1 |
Link Out ? help Back to Top | |
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Phytozome | evm_27.model.AmTr_v1.0_scaffold00030.186 |
Publications ? help Back to Top | |||
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