PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT5G50915.2

Common Name

BHLH137, EN89, K3K7

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 286aa MW: 31773.4 Da PI: 6.4033

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT5G50915.2	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27.6	5.3e-09	146	193	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ +L+ l+P + +k Ka +L + ++Y++ Lq AT5G50915.2 146 SHSLAERVRREKISERMRTLQNLVPGC----DKVTGKALMLDEIINYVQTLQ 193 8***********************9....555**************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	9.68E-17	140	207	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	9.93E-11	140	197	No hit	No description
Gene3D	G3DSA:4.10.280.10	1.8E-16	142	204	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.453	142	192	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.8E-6	146	193	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.0E-9	148	198	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009739	Biological Process	response to gibberellin
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000037	anatomy	shoot apex
PO:0000084	anatomy	plant sperm cell
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025281	anatomy	pollen
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 286 aa Download sequence Send to blast
MATFSYFQNY PHSLLDPLLF PTPHSSINLT SFIDQNHLYP LPNISTVEDI SFLEYNVDKT 60 ENSGSEKLAN TTKTATTGSS SCDQLSHGPS AITNTGKTRG RKARNSNNSK EGVEGRKSKK 120 QKRGSKEEPP TDYIHVRARR GQATDSHSLA ERVRREKISE RMRTLQNLVP GCDKVTGKAL 180 MLDEIINYVQ TLQTQVEFLS MKLTSISPVV YDFGSDLDGL ILQSEMGSPE VGTSFTNAMP 240 TTTPIFPSLL DNSVVPTHAQ VQEEGEEREN FVDRSGFNNN NFCSFP

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.23601	0.0	silique

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	248460_at	0.0
Expression Atlas	AT5G50915	-
AtGenExpress	AT5G50915	-
ATTED-II	AT5G50915	-

Function -- GeneRIF ? help Back to Top
Data show that TTG1-bHLH-MYB complex directly regulating activators and repressors and the movement of repressors to affect trichome patterning on the Arabidopsis leaf. [PMID: 18434419]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT5G50915.2

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT5G50915

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF428350	0.0	AF428350.1 Arabidopsis thaliana unknown protein mRNA, complete cds.
GenBank	AY057549	0.0	AY057549.1 Arabidopsis thaliana probable DNA-binding protein mRNA, complete cds.
GenBank	AY087602	0.0	AY087602.1 Arabidopsis thaliana clone 36971 mRNA, complete sequence.
GenBank	AY113059	0.0	AY113059.1 Arabidopsis thaliana At5g50917/At5g50917 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_568745.1	0.0	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Refseq	NP_851163.1	0.0	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Swissprot	Q93W88	0.0	BH137_ARATH; Transcription factor bHLH137
TrEMBL	A0A178URH5	0.0	A0A178URH5_ARATH; Uncharacterized protein
STRING	AT5G50915.1	0.0	(Arabidopsis thaliana)

Link Out ? help Back to Top
Phytozome	AT5G50915.2
Entrez Gene	835164
iHOP	AT5G50915
wikigenes	AT5G50915

Publications ? help Back to Top
Heim MA, et al. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol., 2003. 20(5): p. 735-47 [PMID:12679534] Toledo-Ortiz G,Huq E,Quail PH The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell, 2003. 15(8): p. 1749-70 [PMID:12897250] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Bailey PC, et al. Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana. Plant Cell, 2003. 15(11): p. 2497-502 [PMID:14600211] Kiba T, et al. Combinatorial microarray analysis revealing arabidopsis genes implicated in cytokinin responses through the His->Asp Phosphorelay circuitry. Plant Cell Physiol., 2005. 46(2): p. 339-55 [PMID:15695462] Hannah MA,Heyer AG,Hincha DK A global survey of gene regulation during cold acclimation in Arabidopsis thaliana. PLoS Genet., 2005. 1(2): p. e26 [PMID:16121258] Cao D,Cheng H,Wu W,Soo HM,Peng J Gibberellin mobilizes distinct DELLA-dependent transcriptomes to regulate seed germination and floral development in Arabidopsis. Plant Physiol., 2006. 142(2): p. 509-25 [PMID:16920880] Lee DJ, et al. Genome-wide expression profiling of ARABIDOPSIS RESPONSE REGULATOR 7(ARR7) overexpression in cytokinin response. Mol. Genet. Genomics, 2007. 277(2): p. 115-37 [PMID:17061125] Bezhani S, et al. Unique, shared, and redundant roles for the Arabidopsis SWI/SNF chromatin remodeling ATPases BRAHMA and SPLAYED. Plant Cell, 2007. 19(2): p. 403-16 [PMID:17293567] Johnston AJ, et al. Genetic subtraction profiling identifies genes essential for Arabidopsis reproduction and reveals interaction between the female gametophyte and the maternal sporophyte. Genome Biol., 2007. 8(10): p. R204 [PMID:17915010] Zentella R, et al. Global analysis of della direct targets in early gibberellin signaling in Arabidopsis. Plant Cell, 2007. 19(10): p. 3037-57 [PMID:17933900] Chan CW,Wohlbach DJ,Rodesch MJ,Sussman MR Transcriptional changes in response to growth of Arabidopsis in high external calcium. FEBS Lett., 2008. 582(6): p. 967-76 [PMID:18307990] Zhao M,Morohashi K,Hatlestad G,Grotewold E,Lloyd A The TTG1-bHLH-MYB complex controls trichome cell fate and patterning through direct targeting of regulatory loci. Development, 2008. 135(11): p. 1991-9 [PMID:18434419] Ascencio-Ib Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. Plant Physiol., 2008. 148(1): p. 436-54 [PMID:18650403] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Josse EM, et al. A DELLA in disguise: SPATULA restrains the growth of the developing Arabidopsis seedling. Plant Cell, 2011. 23(4): p. 1337-51 [PMID:21478445] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]