PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G45050.1
Common NameATWRKY16, K21C13.24, TTR1, WRKY16
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family WRKY
Protein Properties Length: 1372aa    MW: 155701 Da    PI: 6.274
Description Disease resistance protein (TIR-NBS-LRR class)
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G45050.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY89.43e-2811801238259
                   --SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
         WRKY    2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59  
                   +D + WrKYGqK++k+s++prsYYrC+s+ gC ++k+vers++dp+v +itY +eHnh+
  AT5G45050.1 1180 SDLWVWRKYGQKPIKSSPYPRSYYRCASSkGCFARKQVERSRTDPNVSVITYISEHNHP 1238
                   699***********************9988****************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF522005.49E-6898IPR000157Toll/interleukin-1 receptor homology (TIR) domain
SuperFamilySSF525403.43E-49130390IPR027417P-loop containing nucleoside triphosphate hydrolase
PfamPF009312.6E-27154399IPR002182NB-ARC
Gene3DG3DSA:3.40.50.3003.5E-10161285IPR027417P-loop containing nucleoside triphosphate hydrolase
PRINTSPR003647.2E-23165180No hitNo description
PRINTSPR003647.2E-23237251No hitNo description
PRINTSPR003647.2E-23330344No hitNo description
SuperFamilySSF467851.85E-12370467IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:3.40.50.3006.8E-5418469IPR027417P-loop containing nucleoside triphosphate hydrolase
SuperFamilySSF520581.81E-30522821IPR032675Leucine-rich repeat domain, L domain-like
Gene3DG3DSA:3.80.10.102.2E-27534812IPR032675Leucine-rich repeat domain, L domain-like
PfamPF077259.2E-9570589IPR011713Leucine-rich repeat 3
PRINTSPR003647.2E-23744760No hitNo description
Gene3DG3DSA:2.20.25.803.1E-2711661240IPR003657WRKY domain
SuperFamilySSF1182901.44E-2411771240IPR003657WRKY domain
SMARTSM007743.5E-3411791239IPR003657WRKY domain
PROSITE profilePS5081130.74511801240IPR003657WRKY domain
PfamPF031064.5E-2311811238IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0006952Biological Processdefense response
GO:0007165Biological Processsignal transduction
GO:0005634Cellular Componentnucleus
GO:0005774Cellular Componentvacuolar membrane
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0005524Molecular FunctionATP binding
GO:0043531Molecular FunctionADP binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000005anatomycultured plant cell
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 1372 aa     Download sequence    Send to blast
MTESEQIVYI SCIEEVRYSF VSHLSKALQR KGVNDVFIDS DDSLSNESQS MVERARVSVM  60
ILPGNRTVSL DKLVKVLDCQ KNKDQVVVPV LYGVRSSETE WLSALDSKGF SSVHHSRKEC  120
SDSQLVKETV RDVYEKLFYM ERIGIYSKLL EIEKMINKQP LDIRCVGIWG MPGIGKTTLA  180
KAVFDQMSGE FDAHCFIEDY TKAIQEKGVY CLLEEQFLKE NAGASGTVTK LSLLRDRLNN  240
KRVLVVLDDV RSPLVVESFL GGFDWFGPKS LIIITSKDKS VFRLCRVNQI YEVQGLNEKE  300
ALQLFSLCAS IDDMAEQNLH EVSMKVIKYA NGHPLALNLY GRELMGKKRP PEMEIAFLKL  360
KECPPAIFVD AIKSSYDTLN DREKNIFLDI ACFFQGENVD YVMQLLEGCG FFPHVGIDVL  420
VEKSLVTISE NRVRMHNLIQ DVGRQIINRE TRQTKRRSRL WEPCSIKYLL EDKEQNENEE  480
QKTTFERAQV PEEIEGMFLD TSNLSFDIKH VAFDNMLNLR LFKIYSSNPE VHHVNNFLKG  540
SLSSLPNVLR LLHWENYPLQ FLPQNFDPIH LVEINMPYSQ LKKLWGGTKD LEMLKTIRLC  600
HSQQLVDIDD LLKAQNLEVV DLQGCTRLQS FPATGQLLHL RVVNLSGCTE IKSFPEIPPN  660
IETLNLQGTG IIELPLSIVK PNYRELLNLL AEIPGLSGVS NLEQSDLKPL TSLMKISTSY  720
QNPGKLSCLE LNDCSRLRSL PNMVNLELLK ALDLSGCSEL ETIQGFPRNL KELYLVGTAV  780
RQVPQLPQSL EFFNAHGCVS LKSIRLDFKK LPVHYTFSNC FDLSPQVVND FLVQAMANVI  840
AKHIPRERHV TGFSQKTVQR SSRDSQQELN KTLAFSFCAP SHANQNSKLD LQPGSSSMTR  900
LDPSWRNTLV GFAMLVQVAF SEGYCDDTDF GISCVCKWKN KEGHSHRREI NLHCWALGKA  960
VERDHTFVFF DVNMRPDTDE GNDPDIWADL VVFEFFPVNK QRKPLNDSCT VTRCGVRLIT  1020
AVNCNTSIEN ISPVLSLDPM EVSGNEDEEV LRVRYAGLQE IYKALFLYIA GLFNDEDVGL  1080
VAPLIANIID MDVSYGLKVL AYRSLIRVSS NGEIVMHYLL RQMGKEILHT ESKKTDKLVD  1140
NIQSSMIATK EIEITRSKSR RKNNKEKRVV CVVDRGSRSS DLWVWRKYGQ KPIKSSPYPR  1200
SYYRCASSKG CFARKQVERS RTDPNVSVIT YISEHNHPFP TLRNTLAGST RSSSSKCSDV  1260
TTSASSTVSQ DKEGPDKSHL PSSPASPPYA AMVVKEEDME QWDNMEFDVD VEEDTFIPEL  1320
FPEDTFADMD KLEENSQTMF LSRRSSGGNM EAQGKNSSDD REVNLPSKIL NR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4c6s_A4e-4151445150PROBABLE WRKY TRANSCRIPTION FACTOR 52
4c6t_A4e-4121443151PROBABLE WRKY TRANSCRIPTION FACTOR 52
4c6t_C4e-4121443151PROBABLE WRKY TRANSCRIPTION FACTOR 52
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.219090.0flower| leaf| root| seed
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306946740.0
Genevisible248973_at0.0
Expression AtlasAT5G45050-
AtGenExpressAT5G45050-
ATTED-IIAT5G45050-
Functional Description ? help Back to Top
Source Description
TAIREncodes a member of WRKY Transcription Factor (Group II-e) that confers resistance to tobacco ringspot nepovirus.
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Acts also as a disease resistance protein that specifically recognizes the AvrRps4 type III effector avirulence protein from P.syringae. Heterodimerization with RPS4B is required to form a functional complex to recognize AvrRps4 and to mediate the hypersensitive response (PubMed:25744164). {ECO:0000250|UniProtKB:P0DKH5, ECO:0000269|PubMed:25744164}.
Function -- GeneRIF ? help Back to Top
  1. An R gene pair that resembles and is linked to RRS1/RPS4, designated as RRS1B/RPS4B, confers recognition of AvrRps4 from Pseudomonas syringae. [RRS1B]
    [PMID: 25744164]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G45050.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9FL92
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G45050
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0458880.0AY045888.2 Arabidopsis thaliana At5g45050 mRNA sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_851133.10.0Disease resistance protein (TIR-NBS-LRR class)
SwissprotQ9FL920.0RRS1B_ARATH; Disease resistance protein RRS1B
TrEMBLF4KBS50.0F4KBS5_ARATH; Disease resistance protein (TIR-NBS-LRR class)
STRINGAT5G45050.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM2506814
Representative plantOGRP1823
Publications ? help Back to Top
  1. Eulgem T,Rushton PJ,Robatzek S,Somssich IE
    The WRKY superfamily of plant transcription factors.
    Trends Plant Sci., 2000. 5(5): p. 199-206
    [PMID:10785665]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Meyers BC,Kozik A,Griego A,Kuang H,Michelmore RW
    Genome-wide analysis of NBS-LRR-encoding genes in Arabidopsis.
    Plant Cell, 2003. 15(4): p. 809-34
    [PMID:12671079]
  4. Jaquinod M, et al.
    A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture.
    Mol. Cell Proteomics, 2007. 6(3): p. 394-412
    [PMID:17151019]
  5. Tan X, et al.
    Global expression analysis of nucleotide binding site-leucine rich repeat-encoding and related genes in Arabidopsis.
    BMC Plant Biol., 2007. 7: p. 56
    [PMID:17956627]
  6. Chang IF, et al.
    Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana.
    Proteomics, 2009. 9(11): p. 2967-85
    [PMID:19452453]
  7. Saucet SB, et al.
    Two linked pairs of Arabidopsis TNL resistance genes independently confer recognition of bacterial effector AvrRps4.
    Nat Commun, 2015. 6: p. 6338
    [PMID:25744164]
  8. Lee JM,Hartman GL,Domier LL,Bent AF
    Identification and map location of TTR1, a single locus in Arabidopsis thaliana that confers tolerance to tobacco ringspot nepovirus.
    Mol. Plant Microbe Interact., 1996. 9(8): p. 729-35
    [PMID:8870272]
  9. Speulman E,Bouchez D,Holub EB,Beynon JL
    Disease resistance gene homologs correlate with disease resistance loci of Arabidopsis thaliana.
    Plant J., 1998. 14(4): p. 467-74
    [PMID:9670562]