PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT5G43840.1

Common Name

AT-HSFA6A, HSF19, HSFA6A, MQD19.20

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

HSF

Protein Properties

Length: 282aa MW: 33155.6 Da PI: 5.4814

Description

heat shock transcription factor A6A

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT5G43840.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	116.5	1.6e-36	19	112	1	103
HHHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXX CS HSF_DNA-bind 1 aFlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkelleki 97 aFl+k+y+i+ed+++++++sws+++nsf+v+++e+fa +Lp+ Fkh+nf+SFvRQLn+YgFkk+++e+ weF++++F kg+++ll++i AT5G43840.1 19 AFLTKTYNIVEDSSTNNIVSWSRDNNSFIVWEPETFALICLPRCFKHNNFSSFVRQLNTYGFKKIDTER---------WEFANEHFLKGERHLLKNI 106 69**************************************************************999.........*************** PP XXXXXX CS HSF_DNA-bind 98 krkkse 103 kr+k++ AT5G43840.1 107 KRRKTS 112 *986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00415	2.3E-53	16	109	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	1.77E-34	16	109	IPR011991	Winged helix-turn-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	6.0E-36	17	109	IPR011991	Winged helix-turn-helix DNA-binding domain
PRINTS	PR00056	1.4E-17	20	43	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	9.2E-31	20	109	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.4E-17	58	70	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	59	83	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.4E-17	71	83	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0009025	anatomy	vascular leaf
PO:0007115	developmental stage	LP.04 four leaves visible stage

Sequence ? help Back to Top
Protein Sequence Length: 282 aa Download sequence Send to blast
MDYNLPIPLE GLKETPPTAF LTKTYNIVED SSTNNIVSWS RDNNSFIVWE PETFALICLP 60 RCFKHNNFSS FVRQLNTYGF KKIDTERWEF ANEHFLKGER HLLKNIKRRK TSSQTQTQSL 120 EGEIHELRRD RMALEVELVR LRRKQESVKT YLHLMEEKLK VTEVKQEMMM NFLLKKIKKP 180 SFLQSLRKRN LQGIKNREQK QEVISSHGVE DNGKFVKAEP EEYGDDIDDQ CGGVFDYGDE 240 LHIASMEHQG QGEDEIEMDS EGIWKGFVLS EEEMCDLVEH FI

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ldu_A	7e-22	9	112	11	123	Heat shock factor protein 1
5d5u_B	9e-22	4	111	13	131	Heat shock factor protein 1
5d5v_B	9e-22	4	111	13	131	Heat shock factor protein 1
5d5v_D	9e-22	4	111	13	131	Heat shock factor protein 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	102	108	LKNIKRR

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	18422377	0.0
Genevisible	249117_at	0.0
Expression Atlas	AT5G43840	-
AtGenExpress	AT5G43840	-
ATTED-II	AT5G43840	-

Functional Description ? help Back to Top
Source	Description
TAIR	member of Heat Stress Transcription Factor (Hsf) family
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Function -- GeneRIF ? help Back to Top
AtHsfA6a acts as a transcriptional activator of stress-responsive genes via the abscissic acid-dependent signalling pathway. [PMID: 24313737]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00541	DAP	27203113	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT5G43840.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT1G28520

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT5G43840

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	DQ447035	0.0	DQ447035.1 Arabidopsis thaliana clone pENTR221-At5g43840 heat shock transcription factor family protein (At5g43840) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_199197.1	0.0	heat shock transcription factor A6A
Swissprot	Q1PDN3	0.0	HFA6A_ARATH; Heat stress transcription factor A-6a
TrEMBL	A0A178UQY9	0.0	A0A178UQY9_ARATH; HSFA6A
STRING	AT5G43840.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM15683	14	16
Representative plant	OGRP96	17	233

Link Out ? help Back to Top
Phytozome	AT5G43840.1
Entrez Gene	834406
iHOP	AT5G43840
wikigenes	AT5G43840

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Nover L, et al. Arabidopsis and the heat stress transcription factor world: how many heat stress transcription factors do we need? Cell Stress Chaperones, 2001. 6(3): p. 177-89 [PMID:11599559] Jiao Y, et al. A genome-wide analysis of blue-light regulation of Arabidopsis transcription factor gene expression during seedling development. Plant Physiol., 2003. 133(4): p. 1480-93 [PMID:14605227] Underwood BA,Vanderhaeghen R,Whitford R,Town CD,Hilson P Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations. Plant Biotechnol. J., 2006. 4(3): p. 317-24 [PMID:17147637] Osuna D, et al. Temporal responses of transcripts, enzyme activities and metabolites after adding sucrose to carbon-deprived Arabidopsis seedlings. Plant J., 2007. 49(3): p. 463-91 [PMID:17217462] Xin Z,Mandaokar A,Chen J,Last RL,Browse J Arabidopsis ESK1 encodes a novel regulator of freezing tolerance. Plant J., 2007. 49(5): p. 786-99 [PMID:17316173] Zhang X,Wollenweber B,Jiang D,Liu F,Zhao J Water deficits and heat shock effects on photosynthesis of a transgenic Arabidopsis thaliana constitutively expressing ABP9, a bZIP transcription factor. J. Exp. Bot., 2008. 59(4): p. 839-48 [PMID:18272919] Guo J, et al. Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis. J Genet Genomics, 2008. 35(2): p. 105-18 [PMID:18407058] Wohlbach DJ,Quirino BF,Sussman MR Analysis of the Arabidopsis histidine kinase ATHK1 reveals a connection between vegetative osmotic stress sensing and seed maturation. Plant Cell, 2008. 20(4): p. 1101-17 [PMID:18441212] Efroni I, et al. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev. Cell, 2013. 24(4): p. 438-45 [PMID:23449474] Hwang SM, et al. Functional characterization of Arabidopsis HsfA6a as a heat-shock transcription factor under high salinity and dehydration conditions. Plant Cell Environ., 2014. 37(5): p. 1202-22 [PMID:24313737] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Song L, et al. A transcription factor hierarchy defines an environmental stress response network. Science, 2017. [PMID:27811239]