PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT5G20730.3

Common Name

ARF7, BIP, IAA21, IAA23, IAA25, MSG1, NPH4, TIR5

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ARF

Protein Properties

Length: 1150aa MW: 127440 Da PI: 6.9605

Description

ARF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT5G20730.3	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	B3	72.4	5.5e-23	127	228	1	99
EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE.. CS B3 1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefel 92 f+k+lt sd++++g +++p++ ae++ +++++++ +l+ +d + ++W++++iyr++++r++lt+GW+ Fv+ ++L +gD+v+F + + +++l AT5G20730.3 127 FCKTLTASDTSTHGGFSVPRRAAEKIfpaldfSMQPPCQ-ELVAKDIHDNTWTFRHIYRGQPKRHLLTTGWSVFVSTKRLFAGDSVLFIR--DGKAQL 221 99***************************98888885.9**********************************************5..467888 PP EEEEE-S CS B3 93 vvkvfrk 99 +++++r+ AT5G20730.3 222 LLGIRRA 228 9999997 PP
2	Auxin_resp	111.4	9e-37	253	336	1	83
Auxin_resp 1 aahaastksvFevvYnPr.astseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 aaha +++s+F+++YnPr a+++eFvv+++k+ ka++ +vs+GmRf+m fete++ rr++Gtv+g+sdldpvrW+nS+Wr+L+ AT5G20730.3 253 AAHANANNSPFTIFYNPRwAAPAEFVVPLAKYTKAMYAQVSLGMRFRMIFETEECGVRRYMGTVTGISDLDPVRWKNSQWRNLQ 336 799************846789*********************************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101936	1.44E-42	117	256	IPR015300	DNA-binding pseudobarrel domain
Gene3D	G3DSA:2.40.330.10	1.4E-41	121	242	IPR015300	DNA-binding pseudobarrel domain
CDD	cd10017	1.04E-19	126	227	No hit	No description
Pfam	PF02362	3.1E-21	127	228	IPR003340	B3 DNA binding domain
PROSITE profile	PS50863	12.125	127	229	IPR003340	B3 DNA binding domain
SMART	SM01019	9.7E-23	127	229	IPR003340	B3 DNA binding domain
Pfam	PF06507	8.3E-32	253	336	IPR010525	Auxin response factor
Pfam	PF02309	1.7E-9	1036	1124	IPR033389	AUX/IAA domain
PROSITE profile	PS51745	26.956	1038	1131	IPR000270	PB1 domain
SuperFamily	SSF54277	1.03E-8	1051	1116	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009630	Biological Process	gravitropism
GO:0009638	Biological Process	phototropism
GO:0009723	Biological Process	response to ethylene
GO:0009733	Biological Process	response to auxin
GO:0009734	Biological Process	auxin-activated signaling pathway
GO:0009785	Biological Process	blue light signaling pathway
GO:0010311	Biological Process	lateral root formation
GO:0040008	Biological Process	regulation of growth
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0048366	Biological Process	leaf development
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0005515	Molecular Function	protein binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000016	anatomy	lateral root primordium
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009015	anatomy	portion of vascular tissue
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025281	anatomy	pollen
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 1150 aa Download sequence Send to blast
MKAPSSNGVS PNPVEGERRN INSELWHACA GPLISLPPAG SLVVYFPQGH SEQVAASMQK 60 QTDFIPSYPN LPSKLICMLH NVTLNADPET DEVYAQMTLQ PVNKYDRDAL LASDMGLKLN 120 RQPNEFFCKT LTASDTSTHG GFSVPRRAAE KIFPALDFSM QPPCQELVAK DIHDNTWTFR 180 HIYRGQPKRH LLTTGWSVFV STKRLFAGDS VLFIRDGKAQ LLLGIRRANR QQPALSSSVI 240 SSDSMHIGVL AAAAHANANN SPFTIFYNPR WAAPAEFVVP LAKYTKAMYA QVSLGMRFRM 300 IFETEECGVR RYMGTVTGIS DLDPVRWKNS QWRNLQIGWD ESAAGDRPSR VSVWDIEPVL 360 TPFYICPPPF FRPRFSGQPG MPDDETDMES ALKRAMPWLD NSLEMKDPSS TIFPGLSLVQ 420 WMNMQQQNGQ LPSAAAQPGF FPSMLSPTAA LHNNLGGTDD PSKLLSFQTP HGGISSSNLQ 480 FNKQNQQAPM SQLPQPPTTL SQQQQLQQLL HSSLNHQQQQ SQSQQQQQQQ QLLQQQQQLQ 540 SQQHSNNNQS QSQQQQQLLQ QQQQQQLQQQ HQQPLQQQTQ QQQLRTQPLQ SHSHPQPQQL 600 QQHKLQQLQV PQNQLYNGQQ AAQQHQSQQA STHHLQPQLV SGSMASSVIT PPSSSLNQSF 660 QQQQQQSKQL QQAHHHLGAS TSQSSVIETS KSSSNLMSAP PQETQFSRQV EQQQPPGLNG 720 QNQQTLLQQK AHQAQAQQIF QQSLLEQPHI QFQLLQRLQQ QQQQQFLSPQ SQLPHHQLQS 780 QQLQQLPTLS QGHQFPSSCT NNGLSTLQPP QMLVSRPQEK QNPPVGGGVK AYSGITDGGD 840 APSSSTSPST NNCQISSSGF LNRSQSGPAI LIPDAAIDMS GNLVQDLYSK SDMRLKQELV 900 GQQKSKASLT DHQLEASASG TSYGLDGGEN NRQQNFLAPT FGLDGDSRNS LLGGANVDNG 960 FVPDTLLSRG YDSQKDLQNM LSNYGGVTND IGTEMSTSAV RTQSFGVPNV PAISNDLAVN 1020 DAGVLGGGLW PAQTQRMRTY TKVQKRGSVG RSIDVNRYRG YDELRHDLAR MFGIEGQLED 1080 PQTSDWKLVY VDHENDILLV GDDPWEEFVN CVQSIKILSS AEVQQMSLDG NFAGVPVTNQ 1140 ACSGATSFNR

Sequence ? help Back to Top

Protein Sequence Length: 1150 aa Download sequence Send to blast

MKAPSSNGVS PNPVEGERRN INSELWHACA GPLISLPPAG SLVVYFPQGH SEQVAASMQK  60
QTDFIPSYPN LPSKLICMLH NVTLNADPET DEVYAQMTLQ PVNKYDRDAL LASDMGLKLN  120
RQPNEFFCKT LTASDTSTHG GFSVPRRAAE KIFPALDFSM QPPCQELVAK DIHDNTWTFR  180
HIYRGQPKRH LLTTGWSVFV STKRLFAGDS VLFIRDGKAQ LLLGIRRANR QQPALSSSVI  240
SSDSMHIGVL AAAAHANANN SPFTIFYNPR WAAPAEFVVP LAKYTKAMYA QVSLGMRFRM  300
IFETEECGVR RYMGTVTGIS DLDPVRWKNS QWRNLQIGWD ESAAGDRPSR VSVWDIEPVL  360
TPFYICPPPF FRPRFSGQPG MPDDETDMES ALKRAMPWLD NSLEMKDPSS TIFPGLSLVQ  420
WMNMQQQNGQ LPSAAAQPGF FPSMLSPTAA LHNNLGGTDD PSKLLSFQTP HGGISSSNLQ  480
FNKQNQQAPM SQLPQPPTTL SQQQQLQQLL HSSLNHQQQQ SQSQQQQQQQ QLLQQQQQLQ  540
SQQHSNNNQS QSQQQQQLLQ QQQQQQLQQQ HQQPLQQQTQ QQQLRTQPLQ SHSHPQPQQL  600
QQHKLQQLQV PQNQLYNGQQ AAQQHQSQQA STHHLQPQLV SGSMASSVIT PPSSSLNQSF  660
QQQQQQSKQL QQAHHHLGAS TSQSSVIETS KSSSNLMSAP PQETQFSRQV EQQQPPGLNG  720
QNQQTLLQQK AHQAQAQQIF QQSLLEQPHI QFQLLQRLQQ QQQQQFLSPQ SQLPHHQLQS  780
QQLQQLPTLS QGHQFPSSCT NNGLSTLQPP QMLVSRPQEK QNPPVGGGVK AYSGITDGGD  840
APSSSTSPST NNCQISSSGF LNRSQSGPAI LIPDAAIDMS GNLVQDLYSK SDMRLKQELV  900
GQQKSKASLT DHQLEASASG TSYGLDGGEN NRQQNFLAPT FGLDGDSRNS LLGGANVDNG  960
FVPDTLLSRG YDSQKDLQNM LSNYGGVTND IGTEMSTSAV RTQSFGVPNV PAISNDLAVN  1020
DAGVLGGGLW PAQTQRMRTY TKVQKRGSVG RSIDVNRYRG YDELRHDLAR MFGIEGQLED  1080
PQTSDWKLVY VDHENDILLV GDDPWEEFVN CVQSIKILSS AEVQQMSLDG NFAGVPVTNQ  1140
ACSGATSFNR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4ldu_A	1e-167	21	357	51	388	Auxin response factor 5
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.59645	0.0	seed

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	4103242	0.0
Genevisible	245971_at	0.0
Expression Atlas	AT5G20730	-
AtGenExpress	AT5G20730	-
ATTED-II	AT5G20730	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in the whole plant. {ECO:0000269\|PubMed:10476078}.

Functional Description ? help Back to Top
Source	Description
TAIR	Encodes an auxin-regulated transcriptional activator. Activates expression of IAA1 and IAA9 in the presence of auxin. Mutants affect blue light and gravitropic and auxin mediated growth responses. Together with AUX19, it is involved in the response to ethylene. In the arf7 arf19 double mutant, several auxin-responsive genes (e.g. IAA5, LBD16, LBD29 and LBD33) are no longer upregulated by auxin.
UniProt	Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Act as a transcriptional activator of several tropic stimulus-induced (TSI) genes, including SAUR50. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Required for differential growth responses of aerial tissues. Involved in ethylene responses. Regulates lateral root formation through direct regulation of LBD16 and/or LBD29. Functionally redundant with ARF19. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF5. {ECO:0000269\|PubMed:12036261, ECO:0000269\|PubMed:14973283, ECO:0000269\|PubMed:16371470, ECO:0000269\|PubMed:16461383, ECO:0000269\|PubMed:17259263}.

Function -- GeneRIF ? help Back to Top
ARF7 plays a major role in regulating expression of a subset of auxin response genes in leaf mesophyll cells. [PMID: 15923351] Mutations in ARF19 have little effect on their own, but in combination with mutations in NPH4/ARF7, encoding the most closely related ARF, they cause several phenotypes. [PMID: 15960621] ARF7 acts to regulate the auxin-mediated transcription of LATERAL ORGAN BOUNDARIES-DOMAIN16/ASYMMETRIC LEAVES2-LIKE18 (LBD16/ASL18) and/or LBD29/ASL16 in roots. [PMID: 17259263] Reduced upregulation of glycolipid synthase and phospholipase genes in these mutants under Pi-deficient conditions indicates that IAA14 and ARF7/19 affect membrane lipid remodeling at the level of transcription. [PMID: 20043234] Mutations affecting either ARF7 or ARF19 function almost fully blocked manifestation of the sar1-7-dependent ethylene hypersensitivity phenotype. [PMID: 22238449] Brassinosteroids employs auxin signaling components IAA19 and ARF7 to modulate the specific downstream processes. [PMID: 23125315] Data indicate that PIF4 and PIF5 negatively regulate auxin signaling. that PIF4 and PIF5 negatively modulate auxin-mediated phototropism through directly activating IAA19 and IAA29, which physically interact with auxin factor7 (ARF7). [PMID: 23757399] Data indicate that CARBON-METABOLISM INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 (CGA1) expression is repressed by AUXIN RESPONSE FACTO ARF2 and ARF7. [PMID: 23878229] phosphorylation of ARF7 and ARF19 by BRASSINOSTEROID-insensitive2 (BIN2) can also potentiate auxin signalling output during lateral root organogenesis. [PMID: 24362628] the thermodynamic and structural basis for Arabidopsis thaliana ARF7 PB1 domain self-interaction. [PMID: 25839233] Analyses of the expression pattern of ARF7 and ARF5 targets suggest that this patterning mechanism controls flanking and central zone specification in Arabidopsis LR primordia. [PMID: 25944102] ARF7 and FLP transcription factors jointly form a coherent feed-forward motif that mediates the auxin-responsive PIN3 transcription in planta to steer the early steps of lateral root formation. [PMID: 26578065] Transcription factors AUXIN RESPONSE FACTOR7 (ARF7) and ARF19 mutants showed down-regulated expression of PHOSPHATE STARVATION RESPONSE1 (PHR1) and downstream Pi starvation-induced genes in roots. [PMID: 30026290] Epistatic interaction of NPH4 and IAR2 genes in Arabidopsis roots has been reported. [PMID: 30484609] hydropatterning is dependent on auxin response factor ARF7 [PMID: 30573626]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT5G20730.3

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source	Target Gene (A: Activate/R: Repress)
ATRM	AT1G04240(A), AT1G19220(A), AT2G42430(A), AT2G45420(A), AT3G15540(A), AT3G20840(A), AT3G50340(A), AT3G58190(A), AT4G14550(R), AT4G14560(A), AT4G27260(A), AT4G37390(A), AT4G37650(R)

Regulation -- Hormone ? help Back to Top
Source	Hormone
AHD	auxin, ethylene

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT5G20730, AT1G19850, AT1G35240

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT5G20730

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF042195	0.0	AF042195.1 Arabidopsis thaliana auxin response factor 7 (ARF7) mRNA, complete cds.
GenBank	AY669789	0.0	AY669789.1 Arabidopsis thaliana clone C105344 ARF7 (At5g20730) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_568400.2	0.0	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein
Swissprot	P93022	0.0	ARFG_ARATH; Auxin response factor 7
TrEMBL	F4K5M5	0.0	F4K5M5_ARATH; Auxin response factor
STRING	AT5G20730.1	0.0	(Arabidopsis thaliana)

Link Out ? help Back to Top
Phytozome	AT5G20730.3
Entrez Gene	832196
iHOP	AT5G20730
wikigenes	AT5G20730

Publications ? help Back to Top
Ulmasov T,Hagen G,Guilfoyle TJ Activation and repression of transcription by auxin-response factors. Proc. Natl. Acad. Sci. U.S.A., 1999. 96(10): p. 5844-9 [PMID:10318972] Lascève G, et al. Arabidopsis contains at least four independent blue-light-activated signal transduction pathways. Plant Physiol., 1999. 120(2): p. 605-14 [PMID:10364413] Harper RM, et al. The NPH4 locus encodes the auxin response factor ARF7, a conditional regulator of differential growth in aerial Arabidopsis tissue. Plant Cell, 2000. 12(5): p. 757-70 [PMID:10810148] Stepanova AN,Ecker JR Ethylene signaling: from mutants to molecules. Curr. Opin. Plant Biol., 2000. 3(5): p. 353-60 [PMID:11019801] Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Stowe-Evans EL,Luesse DR,Liscum E The enhancement of phototropin-induced phototropic curvature in Arabidopsis occurs via a photoreversible phytochrome A-dependent modulation of auxin responsiveness. Plant Physiol., 2001. 126(2): p. 826-34 [PMID:11402210] M Brassinosteroid-regulated gene expression. Plant Physiol., 2002. 129(3): p. 1241-51 [PMID:12114578] Folta KM,Kaufman LS Phototropin 1 is required for high-fluence blue-light-mediated mRNA destabilization. Plant Mol. Biol., 2003. 51(4): p. 609-18 [PMID:12650626] Tatematsu K, et al. MASSUGU2 encodes Aux/IAA19, an auxin-regulated protein that functions together with the transcriptional activator NPH4/ARF7 to regulate differential growth responses of hypocotyl and formation of lateral roots in Arabidopsis thaliana. Plant Cell, 2004. 16(2): p. 379-93 [PMID:14729917] Takase T, et al. ydk1-D, an auxin-responsive GH3 mutant that is involved in hypocotyl and root elongation. Plant J., 2004. 37(4): p. 471-83 [PMID:14756757] Hardtke CS, et al. Overlapping and non-redundant functions of the Arabidopsis auxin response factors MONOPTEROS and NONPHOTOTROPIC HYPOCOTYL 4. Development, 2004. 131(5): p. 1089-100 [PMID:14973283] Okushima Y, et al. Functional genomic analysis of the AUXIN RESPONSE FACTOR gene family members in Arabidopsis thaliana: unique and overlapping functions of ARF7 and ARF19. Plant Cell, 2005. 17(2): p. 444-63 [PMID:15659631] Weijers D, et al. Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional regulators. EMBO J., 2005. 24(10): p. 1874-85 [PMID:15889151] Wang S,Tiwari SB,Hagen G,Guilfoyle TJ AUXIN RESPONSE FACTOR7 restores the expression of auxin-responsive genes in mutant Arabidopsis leaf mesophyll protoplasts. Plant Cell, 2005. 17(7): p. 1979-93 [PMID:15923351] Wilmoth JC, et al. NPH4/ARF7 and ARF19 promote leaf expansion and auxin-induced lateral root formation. Plant J., 2005. 43(1): p. 118-30 [PMID:15960621] Wang JW, et al. Control of root cap formation by MicroRNA-targeted auxin response factors in Arabidopsis. Plant Cell, 2005. 17(8): p. 2204-16 [PMID:16006581] Ellis CM, et al. AUXIN RESPONSE FACTOR1 and AUXIN RESPONSE FACTOR2 regulate senescence and floral organ abscission in Arabidopsis thaliana. Development, 2005. 132(20): p. 4563-74 [PMID:16176952] Fukaki H,Nakao Y,Okushima Y,Theologis A,Tasaka M Tissue-specific expression of stabilized SOLITARY-ROOT/IAA14 alters lateral root development in Arabidopsis. Plant J., 2005. 44(3): p. 382-95 [PMID:16236149] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Esmon CA, et al. A gradient of auxin and auxin-dependent transcription precedes tropic growth responses. Proc. Natl. Acad. Sci. U.S.A., 2006. 103(1): p. 236-41 [PMID:16371470] Li J,Dai X,Zhao Y A role for auxin response factor 19 in auxin and ethylene signaling in Arabidopsis. Plant Physiol., 2006. 140(3): p. 899-908 [PMID:16461383] Dreher KA,Brown J,Saw RE,Callis J The Arabidopsis Aux/IAA protein family has diversified in degradation and auxin responsiveness. Plant Cell, 2006. 18(3): p. 699-714 [PMID:16489122] Nakamoto D,Ikeura A,Asami T,Yamamoto KT Inhibition of brassinosteroid biosynthesis by either a dwarf4 mutation or a brassinosteroid biosynthesis inhibitor rescues defects in tropic responses of hypocotyls in the arabidopsis mutant nonphototropic hypocotyl 4. Plant Physiol., 2006. 141(2): p. 456-64 [PMID:16632588] Muto H, et al. Fluorescence cross-correlation analyses of the molecular interaction between an Aux/IAA protein, MSG2/IAA19, and protein-protein interaction domains of auxin response factors of arabidopsis expressed in HeLa cells. Plant Cell Physiol., 2006. 47(8): p. 1095-101 [PMID:16854942] Fukaki H,Taniguchi N,Tasaka M PICKLE is required for SOLITARY-ROOT/IAA14-mediated repression of ARF7 and ARF19 activity during Arabidopsis lateral root initiation. Plant J., 2006. 48(3): p. 380-9 [PMID:17010112] Okushima Y,Fukaki H,Onoda M,Theologis A,Tasaka M ARF7 and ARF19 regulate lateral root formation via direct activation of LBD/ASL genes in Arabidopsis. Plant Cell, 2007. 19(1): p. 118-30 [PMID:17259263] Shin R, et al. The Arabidopsis transcription factor MYB77 modulates auxin signal transduction. Plant Cell, 2007. 19(8): p. 2440-53 [PMID:17675404] Cheng Y,Qin G,Dai X,Zhao Y NPY1, a BTB-NPH3-like protein, plays a critical role in auxin-regulated organogenesis in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2007. 104(47): p. 18825-9 [PMID:18000043] Ivanchenko MG,Muday GK,Dubrovsky JG Ethylene-auxin interactions regulate lateral root initiation and emergence in Arabidopsis thaliana. Plant J., 2008. 55(2): p. 335-47 [PMID:18435826] Uehara T,Okushima Y,Mimura T,Tasaka M,Fukaki H Domain II mutations in CRANE/IAA18 suppress lateral root formation and affect shoot development in Arabidopsis thaliana. Plant Cell Physiol., 2008. 49(7): p. 1025-38 [PMID:18505759] Ascencio-Ib Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. Plant Physiol., 2008. 148(1): p. 436-54 [PMID:18650403] de Jong M,Wolters-Arts M,Feron R,Mariani C,Vriezen WH The Solanum lycopersicum auxin response factor 7 (SlARF7) regulates auxin signaling during tomato fruit set and development. Plant J., 2009. 57(1): p. 160-70 [PMID:18778404] Ditengou FA, et al. Mechanical induction of lateral root initiation in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A., 2008. 105(48): p. 18818-23 [PMID:19033199] Pérez-Torres CA, et al. Phosphate availability alters lateral root development in Arabidopsis by modulating auxin sensitivity via a mechanism involving the TIR1 auxin receptor. Plant Cell, 2008. 20(12): p. 3258-72 [PMID:19106375] Lee DJ,Park JW,Lee HW,Kim J Genome-wide analysis of the auxin-responsive transcriptome downstream of iaa1 and its expression analysis reveal the diversity and complexity of auxin-regulated gene expression. J. Exp. Bot., 2009. 60(13): p. 3935-57 [PMID:19654206] Sato A,Yamamoto KT What's the physiological role of domain II-less Aux/IAA proteins? Plant Signal Behav, 2008. 3(7): p. 496-7 [PMID:19704497] Lee HW,Kim NY,Lee DJ,Kim J LBD18/ASL20 regulates lateral root formation in combination with LBD16/ASL18 downstream of ARF7 and ARF19 in Arabidopsis. Plant Physiol., 2009. 151(3): p. 1377-89 [PMID:19717544] Stone BB, et al. Disruptions in AUX1-dependent auxin influx alter hypocotyl phototropism in Arabidopsis. Mol Plant, 2008. 1(1): p. 129-44 [PMID:20031920] Narise T, et al. Involvement of auxin signaling mediated by IAA14 and ARF7/19 in membrane lipid remodeling during phosphate starvation. Plant Mol. Biol., 2010. 72(4-5): p. 533-44 [PMID:20043234] De Smet I, et al. Bimodular auxin response controls organogenesis in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(6): p. 2705-10 [PMID:20133796] Ikeyama Y,Tasaka M,Fukaki H RLF, a cytochrome b(5)-like heme/steroid binding domain protein, controls lateral root formation independently of ARF7/19-mediated auxin signaling in Arabidopsis thaliana. Plant J., 2010. 62(5): p. 865-75 [PMID:20230485] Hanada K, et al. Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana. Mol. Biol. Evol., 2011. 28(1): p. 377-82 [PMID:20736450] Varaud E, et al. AUXIN RESPONSE FACTOR8 regulates Arabidopsis petal growth by interacting with the bHLH transcription factor BIGPETALp. Plant Cell, 2011. 23(3): p. 973-83 [PMID:21421811] Ortiz-Castro R, et al. Transkingdom signaling based on bacterial cyclodipeptides with auxin activity in plants. Proc. Natl. Acad. Sci. U.S.A., 2011. 108(17): p. 7253-8 [PMID:21482761] Vernoux T, et al. The auxin signalling network translates dynamic input into robust patterning at the shoot apex. Mol. Syst. Biol., 2011. 7: p. 508 [PMID:21734647] Robles LM,Deslauriers SD,Alvarez AA,Larsen PB A loss-of-function mutation in the nucleoporin AtNUP160 indicates that normal auxin signalling is required for a proper ethylene response in Arabidopsis. J. Exp. Bot., 2012. 63(5): p. 2231-41 [PMID:22238449] Goh T,Joi S,Mimura T,Fukaki H The establishment of asymmetry in Arabidopsis lateral root founder cells is regulated by LBD16/ASL18 and related LBD/ASL proteins. Development, 2012. 139(5): p. 883-93 [PMID:22278921] Grunewald W, et al. Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis. Proc. Natl. Acad. Sci. U.S.A., 2012. 109(5): p. 1554-9 [PMID:22307611] Feng Z,Sun X,Wang G,Liu H,Zhu J LBD29 regulates the cell cycle progression in response to auxin during lateral root formation in Arabidopsis thaliana. Ann. Bot., 2012. 110(1): p. 1-10 [PMID:22334497] Raya-Gonz The jasmonate receptor COI1 plays a role in jasmonate-induced lateral root formation and lateral root positioning in Arabidopsis thaliana. J. Plant Physiol., 2012. 169(14): p. 1348-58 [PMID:22658222] Feng Z,Zhu J,Du X,Cui X Effects of three auxin-inducible LBD members on lateral root formation in Arabidopsis thaliana. Planta, 2012. 236(4): p. 1227-37 [PMID:22699776] Arase F, et al. IAA8 involved in lateral root formation interacts with the TIR1 auxin receptor and ARF transcription factors in Arabidopsis. PLoS ONE, 2012. 7(8): p. e43414 [PMID:22912871] Zhou XY,Song L,Xue HW Brassinosteroids regulate the differential growth of Arabidopsis hypocotyls through auxin signaling components IAA19 and ARF7. Mol Plant, 2013. 6(3): p. 887-904 [PMID:23125315] Guo X,Lu W,Ma Y,Qin Q,Hou S The BIG gene is required for auxin-mediated organ growth in Arabidopsis. Planta, 2013. 237(4): p. 1135-47 [PMID:23288076] Kim J,Lee HW Direct activation of EXPANSIN14 by LBD18 in the gene regulatory network of lateral root formation in Arabidopsis. Plant Signal Behav, 2013. 8(2): p. e22979 [PMID:23299420] Wang J,Yan DW,Yuan TT,Gao X,Lu YT A gain-of-function mutation in IAA8 alters Arabidopsis floral organ development by change of jasmonic acid level. Plant Mol. Biol., 2013. 82(1-2): p. 71-83 [PMID:23483289] Hofhuis H, et al. Phyllotaxis and rhizotaxis in Arabidopsis are modified by three PLETHORA transcription factors. Curr. Biol., 2013. 23(11): p. 956-62 [PMID:23684976] Kang NY,Lee HW,Kim J The AP2/EREBP gene PUCHI Co-Acts with LBD16/ASL18 and LBD18/ASL20 downstream of ARF7 and ARF19 to regulate lateral root development in Arabidopsis. Plant Cell Physiol., 2013. 54(8): p. 1326-34 [PMID:23749813] Sun J,Qi L,Li Y,Zhai Q,Li C PIF4 and PIF5 transcription factors link blue light and auxin to regulate the phototropic response in Arabidopsis. Plant Cell, 2013. 25(6): p. 2102-14 [PMID:23757399] Richter R,Behringer C,Zourelidou M,Schwechheimer C Convergence of auxin and gibberellin signaling on the regulation of the GATA transcription factors GNC and GNL in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(32): p. 13192-7 [PMID:23878229] Cho H, et al. A secreted peptide acts on BIN2-mediated phosphorylation of ARFs to potentiate auxin response during lateral root development. Nat. Cell Biol., 2014. 16(1): p. 66-76 [PMID:24362628] Hu J,Zhang Y,Wang J,Zhou Y Glycerol affects root development through regulation of multiple pathways in Arabidopsis. PLoS ONE, 2014. 9(1): p. e86269 [PMID:24465999] Korasick DA, et al. Molecular basis for AUXIN RESPONSE FACTOR protein interaction and the control of auxin response repression. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(14): p. 5427-32 [PMID:24706860] Mellor N, et al. Modelling of Arabidopsis LAX3 expression suggests auxin homeostasis. J. Theor. Biol., 2015. 366: p. 57-70 [PMID:25446711] Piya S,Shrestha SK,Binder B,Stewart CN,Hewezi T Protein-protein interaction and gene co-expression maps of ARFs and Aux/IAAs in Arabidopsis. Front Plant Sci, 2014. 5: p. 744 [PMID:25566309] Jin J, et al. An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors. Mol. Biol. Evol., 2015. 32(7): p. 1767-73 [PMID:25750178] Gupta A,Singh M,Laxmi A Interaction between glucose and brassinosteroid during the regulation of lateral root development in Arabidopsis. Plant Physiol., 2015. 168(1): p. 307-20 [PMID:25810094] Korasick DA, et al. Defining a two-pronged structural model for PB1 (Phox/Bem1p) domain interaction in plant auxin responses. J. Biol. Chem., 2015. 290(20): p. 12868-78 [PMID:25839233] Lavenus J, et al. Inference of the Arabidopsis lateral root gene regulatory network suggests a bifurcation mechanism that defines primordia flanking and central zones. Plant Cell, 2015. 27(5): p. 1368-88 [PMID:25944102] Chen Q, et al. A coherent transcriptional feed-forward motif model for mediating auxin-sensitive PIN3 expression during lateral root development. Nat Commun, 2015. 6: p. 8821 [PMID:26578065] Youn JH, et al. ARF7 increases the endogenous contents of castasterone through suppression of BAS1 expression in Arabidopsis thaliana. Phytochemistry, 2016. 122: p. 34-44 [PMID:26608667] Porco S, et al. Lateral root emergence in Arabidopsis is dependent on transcription factor LBD29 regulation of auxin influx carrier LAX3. Development, 2016. 143(18): p. 3340-9 [PMID:27578783] Carey NS,Krogan NT The role of AUXIN RESPONSE FACTORs in the development and differential growth of inflorescence stems. Plant Signal Behav, 2017. 12(4): p. e1307492 [PMID:28340328] Olmo R, et al. Molecular Transducers from Roots Are Triggered in Arabidopsis Leaves by Root-Knot Nematodes for Successful Feeding Site Formation: A Conserved Post-Embryogenic De novo Organogenesis Program? Front Plant Sci, 2017. 8: p. 875 [PMID:28603536] Sheng L, et al. Non-canonical WOX11-mediated root branching contributes to plasticity in Arabidopsis root system architecture. Development, 2017. 144(17): p. 3126-3133 [PMID:28743799] Lee K,Seo PJ High-temperature promotion of callus formation requires the BIN2-ARF-LBD axis in Arabidopsis. Planta, 2017. 246(4): p. 797-802 [PMID:28766014] Ayala-Rodríguez JÁ,Barrera-Ortiz S,Ruiz-Herrera LF,López-Bucio J Folic acid orchestrates root development linking cell elongation with auxin response and acts independently of the TARGET OF RAPAMYCIN signaling in Arabidopsis thaliana. Plant Sci., 2017. 264: p. 168-178 [PMID:28969797] Nakamura M, et al. Auxin and ROP GTPase Signaling of Polar Nuclear Migration in Root Epidermal Hair Cells. Plant Physiol., 2018. 176(1): p. 378-391 [PMID:29084900] Hong L, et al. Alternative polyadenylation is involved in auxin-based plant growth and development. Plant J., 2018. 93(2): p. 246-258 [PMID:29155478] Lee K,Park OS,Seo PJ Arabidopsis ATXR2 deposits H3K36me3 at the promoters of LBD genes to facilitate cellular dedifferentiation. Sci Signal, 2018. [PMID:29184030] Prát T, et al. WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity. PLoS Genet., 2018. 14(1): p. e1007177 [PMID:29377885] Kimura T, et al. Asymmetric Auxin Distribution is Not Required to Establish Root Phototropism in Arabidopsis. Plant Cell Physiol., 2018. 59(4): p. 823-835 [PMID:29401292] Schoenaers S, et al. The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition during Root Hair Tip Growth. Curr. Biol., 2018. 28(5): p. 722-732.e6 [PMID:29478854] Huang KL, et al. The ARF7 and ARF19 Transcription Factors Positively Regulate PHOSPHATE STARVATION RESPONSE1 in Arabidopsis Roots. Plant Physiol., 2018. 178(1): p. 413-427 [PMID:30026290] Hablak SG Features inheritance of root system Arabidopsis thaliana (L.) Heynh. the interaction of genes CTR1 AND ALF3, NPH4 and IAR2. Tsitol. Genet., 2019. [PMID:30484609] Orosa-Puente B, et al. Root branching toward water involves posttranslational modification of transcription factor ARF7. Science, 2018. 362(6421): p. 1407-1410 [PMID:30573626] Liscum E,Briggs WR Mutations in the NPH1 locus of Arabidopsis disrupt the perception of phototropic stimuli. Plant Cell, 1995. 7(4): p. 473-85 [PMID:7773019] Liscum E,Briggs WR Mutations of Arabidopsis in potential transduction and response components of the phototropic signaling pathway. Plant Physiol., 1996. 112(1): p. 291-6 [PMID:8819327] Ruegger M, et al. Reduced naphthylphthalamic acid binding in the tir3 mutant of Arabidopsis is associated with a reduction in polar auxin transport and diverse morphological defects. Plant Cell, 1997. 9(5): p. 745-57 [PMID:9165751] Kim J,Harter K,Theologis A Protein-protein interactions among the Aux/IAA proteins. Proc. Natl. Acad. Sci. U.S.A., 1997. 94(22): p. 11786-91 [PMID:9342315] Watahiki MK,Yamamoto KT The massugu1 mutation of Arabidopsis identified with failure of auxin-induced growth curvature of hypocotyl confers auxin insensitivity to hypocotyl and leaf. Plant Physiol., 1997. 115(2): p. 419-26 [PMID:9342863] Stowe-Evans EL,Harper RM,Motchoulski AV,Liscum E NPH4, a conditional modulator of auxin-dependent differential growth responses in Arabidopsis. Plant Physiol., 1998. 118(4): p. 1265-75 [PMID:9847100] Watahiki MK,Tatematsu K,Fujihira K,Yamamoto M,Yamamoto KT The MSG1 and AXR1 genes of Arabidopsis are likely to act independently in growth-curvature responses of hypocotyls. Planta, 1999. 207(3): p. 362-9 [PMID:9951732]