PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT5G11190.1

Common Name

ERF004, F2I11.80, SHN2

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 189aa MW: 21409.3 Da PI: 6.1391

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT5G11190.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	58.6	1.6e-18	6	55	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr..krfslgkfgtaeeAakaaiaarkkleg 55 +++GVr++ +g+Wv+eIr+p +r++lg+f tae Aa+a+++a++ ++g AT5G11190.1 6 KFRGVRQRQ-WGSWVSEIRHP-----LlkRRVWLGTFETAEAAARAYDQAALLMNG 55 89**999.******8.....334********************98877 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.730.10	1.8E-32	5	64	IPR001471	AP2/ERF domain
CDD	cd00018	8.82E-23	6	65	No hit	No description
Pfam	PF00847	1.2E-11	6	55	IPR001471	AP2/ERF domain
SMART	SM00380	3.0E-39	6	69	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	5.89E-20	6	64	IPR016177	DNA-binding domain
PROSITE profile	PS51032	22.221	6	63	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.9E-10	7	18	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.9E-10	29	45	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000293	anatomy	guard cell
PO:0004707	anatomy	fruit dehiscence zone
PO:0005011	anatomy	anther dehiscence zone

Sequence ? help Back to Top
Protein Sequence Length: 189 aa Download sequence Send to blast
MVHSRKFRGV RQRQWGSWVS EIRHPLLKRR VWLGTFETAE AAARAYDQAA LLMNGQNAKT 60 NFPVVKSEEG SDHVKDVNSP LMSPKSLSEL LNAKLRKSCK DLTPSLTCLR LDTDSSHIGV 120 WQKRAGSKTS PTWVMRLELG NVVNESAVDL GLTTMNKQNV EKEEEEEEAI ISDEDQLAME 180 MIEELLNWS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	1e-16	6	63	14	72	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	18416491	0.0
Expression Atlas	AT5G11190	-
AtGenExpress	AT5G11190	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: The SHN2 gene shows a pattern of expression associated with anther and silique dehiscence. Expressed in the stomium region when tapetum degeneration is initiated in the anther. Up to anthesis and until stamens fell off the senescing flower, restricted to the anther dehiscence zone. Subsequently, when petals and sepals withered, found at the bottom of each valve. During silique development, strongly expressed along the valve margin-replum boundary. {ECO:0000269\|PubMed:15319479}.
Uniprot	TISSUE SPECIFICITY: In flowers. {ECO:0000269\|PubMed:15319479}.

Functional Description ? help Back to Top
Source	Description
TAIR	encodes a member of the ERF (ethylene response factor) subfamily B-6 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 12 members in this subfamily including RAP2.11.
UniProt	Promotes cuticle formation by inducing the expression of enzymes involved in wax biosynthesis. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:15319479}.

Function -- GeneRIF ? help Back to Top
Silencing SHINE clade genes (SHN1/SHN2/SHN3) reduces flower cutin load and modifies petal cell wall structure. [PMID: 21637781]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT5G11190.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT5G11190

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY560865	0.0	AY560865.1 Arabidopsis thaliana putative AP2/EREBP transcription factor (At5g11190) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_196680.1	1e-138	Integrase-type DNA-binding superfamily protein
Swissprot	Q9LFN7	1e-139	SHN2_ARATH; Ethylene-responsive transcription factor SHINE 2
TrEMBL	A0A178UNH8	1e-124	A0A178UNH8_ARATH; SHN2
STRING	AT5G11190.1	1e-137	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM834	28	116
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT5G11190.1
Entrez Gene	830989
iHOP	AT5G11190
wikigenes	AT5G11190

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Broun P,Poindexter P,Osborne E,Jiang CZ,Riechmann JL WIN1, a transcriptional activator of epidermal wax accumulation in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2004. 101(13): p. 4706-11 [PMID:15070782] Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes. Plant J., 2004. 38(2): p. 366-79 [PMID:15078338] Aharoni A, et al. The SHINE clade of AP2 domain transcription factors activates wax biosynthesis, alters cuticle properties, and confers drought tolerance when overexpressed in Arabidopsis. Plant Cell, 2004. 16(9): p. 2463-80 [PMID:15319479] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Shi JX, et al. SHINE transcription factors act redundantly to pattern the archetypal surface of Arabidopsis flower organs. PLoS Genet., 2011. 7(5): p. e1001388 [PMID:21637781] Lisso J,Schr NFXL2 modifies cuticle properties in Arabidopsis. Plant Signal Behav, 2012. 7(5): p. 551-5 [PMID:22516817] Efroni I, et al. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev. Cell, 2013. 24(4): p. 438-45 [PMID:23449474] Li-Beisson Y, et al. Acyl-lipid metabolism. Arabidopsis Book, 2013. 11: p. e0161 [PMID:23505340] Djemal R,Khoudi H Isolation and molecular characterization of a novel WIN1/SHN1 ethylene-responsive transcription factor TdSHN1 from durum wheat (Triticum turgidum. L. subsp. durum). Protoplasma, 2015. 252(6): p. 1461-73 [PMID:25687296] Liu Y, et al. Functional Characterization of Populus PsnSHN2 in Coordinated Regulation of Secondary Wall Components in Tobacco. Sci Rep, 2017. 7(1): p. 42 [PMID:28246387] Kumar V, et al. A part of the upstream promoter region of SHN2 gene directs trichome specific expression in Arabidopsis thaliana and heterologous plants. Plant Sci., 2017. 264: p. 138-148 [PMID:28969794]