PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G38960.3
Common NameBBX19
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family DBB
Protein Properties Length: 226aa    MW: 25116.6 Da    PI: 6.2942
Description DBB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G38960.3genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-B_box21.16.7e-07434534
     zf-B_box  5 kCpeHeekelqlfCedCqqllCedCllee.H 34
                  C+ +e+  +++fC  ++  lC+ C ++  H
  AT4G38960.3  4 LCDACENAAAIIFCAADEAALCRPCDEKAlH 34
                 6*******9*****************98777 PP
2zf-B_box26.21.6e-0895134237
     zf-B_box   2 eerkCpeHeekelqlfCedCqqllCedClleeHkg....H 37 
                  ++++C+ +e+ ++ ++Ce +++ lC +C +  H g    H
  AT4G38960.3  95 NAPCCDICENAPAFFYCEIDGSSLCLQCDMVVHVGgkrtH 134
                  789***************************9996555556 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS501199.869134IPR000315B-box-type zinc finger
CDDcd000217.35E-4330No hitNo description
SMARTSM003360.058439IPR000315B-box-type zinc finger
SMARTSM003362.2E-1294139IPR000315B-box-type zinc finger
PROSITE profilePS501198.91694139IPR000315B-box-type zinc finger
PfamPF006432.5E-695134IPR000315B-box-type zinc finger
CDDcd000211.79E-799139No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007623Biological Processcircadian rhythm
GO:0010100Biological Processnegative regulation of photomorphogenesis
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:0005634Cellular Componentnucleus
GO:0000989Molecular Functiontranscription factor activity, transcription factor binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020100anatomyhypocotyl
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 226 aa     Download sequence    Send to blast
MRILCDACEN AAAIIFCAAD EAALCRPCDE KALHMRLDIS KCSESVKRVQ IVETSSLIWW  60
IKMGTFCLQS LHLVVHMCNK LASRHVRVGL AEPSNAPCCD ICENAPAFFY CEIDGSSLCL  120
QCDMVVHVGG KRTHGRFLLL RQRIEFPGDK PKENNTRDNL QNQRVSTNGN GEANGKIDDE  180
MIDLNANPQR VHEPSSNNNG IDVNNENNHE PAGLVPVGPF KRESEK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.726070.0bud| flower| leaf| root| seed| silique
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible252917_at1e-113
Expression AtlasAT4G38960-
AtGenExpressAT4G38960-
ATTED-IIAT4G38960-
Functional Description ? help Back to Top
Source Description
UniProtActs as negative regulator of seedling photomorphogenesis. {ECO:0000269|PubMed:18540109}.
Function -- GeneRIF ? help Back to Top
  1. Results implicate BBX19 as a circadian clock output that depletes the active CO pool to accurately monitor daylength and precisely time FT expression.[BBX19]
    [PMID: 25228341]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G38960.3
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G15840
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G38960
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0109270.0BT010927.1 Arabidopsis thaliana At4g38960 gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001190958.11e-168B-box type zinc finger family protein
SwissprotC0SVM51e-126BBX19_ARATH; B-box zinc finger protein 19
TrEMBLF4JUJ11e-167F4JUJ1_ARATH; B-box type zinc finger family protein
STRINGAT4G38960.31e-167(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM21682469
Representative plantOGRP33521628
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Fowler S,Thomashow MF
    Arabidopsis transcriptome profiling indicates that multiple regulatory pathways are activated during cold acclimation in addition to the CBF cold response pathway.
    Plant Cell, 2002. 14(8): p. 1675-90
    [PMID:12172015]
  3. Hudson ME,Lisch DR,Quail PH
    The FHY3 and FAR1 genes encode transposase-related proteins involved in regulation of gene expression by the phytochrome A-signaling pathway.
    Plant J., 2003. 34(4): p. 453-71
    [PMID:12753585]
  4. S
    ABA activates ADPR cyclase and cADPR induces a subset of ABA-responsive genes in Arabidopsis.
    Plant J., 2004. 38(3): p. 381-95
    [PMID:15086800]
  5. Tepperman JM, et al.
    Expression profiling of phyB mutant demonstrates substantial contribution of other phytochromes to red-light-regulated gene expression during seedling de-etiolation.
    Plant J., 2004. 38(5): p. 725-39
    [PMID:15144375]
  6. Vogel JT,Zarka DG,Van Buskirk HA,Fowler SG,Thomashow MF
    Roles of the CBF2 and ZAT12 transcription factors in configuring the low temperature transcriptome of Arabidopsis.
    Plant J., 2005. 41(2): p. 195-211
    [PMID:15634197]
  7. Stanley Kim H, et al.
    Transcriptional divergence of the duplicated oxidative stress-responsive genes in the Arabidopsis genome.
    Plant J., 2005. 41(2): p. 212-20
    [PMID:15634198]
  8. Kumagai T, et al.
    The common function of a novel subfamily of B-Box zinc finger proteins with reference to circadian-associated events in Arabidopsis thaliana.
    Biosci. Biotechnol. Biochem., 2008. 72(6): p. 1539-49
    [PMID:18540109]
  9. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  10. Datta S, et al.
    LZF1/SALT TOLERANCE HOMOLOG3, an Arabidopsis B-box protein involved in light-dependent development and gene expression, undergoes COP1-mediated ubiquitination.
    Plant Cell, 2008. 20(9): p. 2324-38
    [PMID:18796637]
  11. Khanna R, et al.
    The Arabidopsis B-box zinc finger family.
    Plant Cell, 2009. 21(11): p. 3416-20
    [PMID:19920209]
  12. Li G, et al.
    Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis.
    Nat. Cell Biol., 2011. 13(5): p. 616-22
    [PMID:21499259]
  13. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  14. Yamawaki S,Yamashino T,Nakamichi N,Nakanishi H,Mizuno T
    Light-responsive double B-box containing transcription factors are conserved in Physcomitrella patens.
    Biosci. Biotechnol. Biochem., 2011. 75(10): p. 2037-41
    [PMID:21979077]
  15. Wang CQ,Guthrie C,Sarmast MK,Dehesh K
    BBX19 interacts with CONSTANS to repress FLOWERING LOCUS T transcription, defining a flowering time checkpoint in Arabidopsis.
    Plant Cell, 2014. 26(9): p. 3589-602
    [PMID:25228341]
  16. Wang CQ,Sarmast MK,Jiang J,Dehesh K
    The Transcriptional Regulator BBX19 Promotes Hypocotyl Growth by Facilitating COP1-Mediated EARLY FLOWERING3 Degradation in Arabidopsis.
    Plant Cell, 2015. 27(4): p. 1128-39
    [PMID:25841036]