PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT4G34410.1

Common Name

ERF109, F10M10.180, RRTF1

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 268aa MW: 29446.7 Da PI: 6.2918

Description

redox responsive transcription factor 1

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT4G34410.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.3	9.4e-19	135	184	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 gy+GVr+++ +g+++AeIrdp+ r +r++lg+f tae+Aa+a+++a+ ++g AT4G34410.1 135 GYRGVRQRP-WGKFAAEIRDPK----RaTRVWLGTFETAEDAARAYDRAAIGFRG 184 8******.******83....57*******************987776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	1.11E-21	135	193	IPR016177	DNA-binding domain
SMART	SM00380	2.1E-37	135	198	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.012	135	192	IPR001471	AP2/ERF domain
Pfam	PF00847	3.7E-12	135	183	IPR001471	AP2/ERF domain
CDD	cd00018	2.09E-21	136	192	No hit	No description
Gene3D	G3DSA:3.30.730.10	6.0E-32	136	192	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.4E-11	136	147	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.4E-11	158	174	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0001944	Biological Process	vasculature development
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0010200	Biological Process	response to chitin
GO:0050832	Biological Process	defense response to fungus
GO:0051301	Biological Process	cell division
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009009	anatomy	plant embryo
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025281	anatomy	pollen
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 268 aa Download sequence Send to blast
MHYPNNRTEF VGAPAPTRYQ KEQLSPEQEL SVIVSALQHV ISGENETAPC QGFSSDSTVI 60 SAGMPRLDSD TCQVCRIEGC LGCNYFFAPN QRIEKNHQQE EEITSSSNRR RESSPVAKKA 120 EGGGKIRKRK NKKNGYRGVR QRPWGKFAAE IRDPKRATRV WLGTFETAED AARAYDRAAI 180 GFRGPRAKLN FPFVDYTSSV SSPVAADDIG AKASASASVS ATDSVEAEQW NGGGGDCNME 240 EWMNMMMMMD FGNGDSSDSG NTIADMFQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	7e-25	132	193	2	64	ATERF1
3gcc_A	7e-25	132	193	2	64	ATERF1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	108	129	RRRESSPVAKKAEGGGKIRKRK

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.48936	0.0	bud\| floral meristem\| leaf\| root

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	30690021	0.0
Genevisible	253259_at	0.0
Expression Atlas	AT4G34410	-
AtGenExpress	AT4G34410	-
ATTED-II	AT4G34410	-

Functional Description ? help Back to Top
Source	Description
TAIR	encodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 18 members in this subfamily including ATERF-1, ATERF-2, AND ATERF-5.
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Function -- GeneRIF ? help Back to Top
RRTF1 has a role in regulating redox homeostasis related to photosynthetic stress. [RRTF1] [PMID: 18829981] ERF109 mediates cross-talk between jasmonic acid and auxin biosynthesis during lateral root formation. [PMID: 25524530] inactivation of RRTF1 restricts and overexpression promotes reactive oxygen species (ROS) accumulation in response to stress. [PMID: 25882345] RRTF1 and/or RRTF1-mediated ROS signaling induce stress responses in an age-dependent manner, and the age-dependent alteration in the RRTF1 function might be important for plant's acclimation to the stress environment.[RRTF1] [PMID: 26479402] Results show that the RRTF1 promoter is sufficient for the control of both activation and adaptation to salt stress. As constitutive expression of RRTF1 turned out to be detrimental to the plant, results propose that promoter-regulated adaptation evolved as a protection mechanism to balance the beneficial effects of short-term gene activation and the detrimental effects of long-term gene expression. [PMID: 30734200]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00469	DAP	27203113	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT4G34410.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT4G34410

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF325091	0.0	AF325091.1 Arabidopsis thaliana putative protein (F10M10.180) mRNA, complete cds.
GenBank	AL035521	0.0	AL035521.1 Arabidopsis thaliana DNA chromosome 4, BAC clone F10M10 (ESSA project).
GenBank	AL161585	0.0	AL161585.2 Arabidopsis thaliana DNA chromosome 4, contig fragment No. 81.
GenBank	AY064151	0.0	AY064151.1 Arabidopsis thaliana AT4g34410/F10M10_180 mRNA, complete cds.
GenBank	AY120700	0.0	AY120700.1 Arabidopsis thaliana AT4g34410/F10M10_180 mRNA, complete cds.
GenBank	CP002687	0.0	CP002687.1 Arabidopsis thaliana chromosome 4 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_195167.1	0.0	redox responsive transcription factor 1
Swissprot	Q9SZ06	0.0	EF109_ARATH; Ethylene-responsive transcription factor ERF109
TrEMBL	A0A178UVP9	0.0	A0A178UVP9_ARATH; RRTF1
STRING	AT4G34410.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5469	24	49
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT4G34410.1
Entrez Gene	829591
iHOP	AT4G34410
wikigenes	AT4G34410

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] M Brassinosteroids promote root growth in Arabidopsis. Plant Physiol., 2003. 133(3): p. 1261-71 [PMID:14526105] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Chang S,Pikaard CS Transcript profiling in Arabidopsis reveals complex responses to global inhibition of DNA methylation and histone deacetylation. J. Biol. Chem., 2005. 280(1): p. 796-804 [PMID:15516340] Suzuki N, et al. Enhanced tolerance to environmental stress in transgenic plants expressing the transcriptional coactivator multiprotein bridging factor 1c. Plant Physiol., 2005. 139(3): p. 1313-22 [PMID:16244138] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Tang M,Sun J,Liu Y,Chen F,Shen S Isolation and functional characterization of the JcERF gene, a putative AP2/EREBP domain-containing transcription factor, in the woody oil plant Jatropha curcas. Plant Mol. Biol., 2007. 63(3): p. 419-28 [PMID:17103014] Lee J, et al. Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development. Plant Cell, 2007. 19(3): p. 731-49 [PMID:17337630] Kong H, et al. Patterns of gene duplication in the plant SKP1 gene family in angiosperms: evidence for multiple mechanisms of rapid gene birth. Plant J., 2007. 50(5): p. 873-85 [PMID:17470057] Libault M,Wan J,Czechowski T,Udvardi M,Stacey G Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor. Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11 [PMID:17722694] Wang Z, et al. Identification and characterization of COI1-dependent transcription factor genes involved in JA-mediated response to wounding in Arabidopsis plants. Plant Cell Rep., 2008. 27(1): p. 125-35 [PMID:17786451] Cartagena JA, et al. The Arabidopsis SDG4 contributes to the regulation of pollen tube growth by methylation of histone H3 lysines 4 and 36 in mature pollen. Dev. Biol., 2008. 315(2): p. 355-68 [PMID:18252252] Veyres N, et al. The Arabidopsis sweetie mutant is affected in carbohydrate metabolism and defective in the control of growth, development and senescence. Plant J., 2008. 55(4): p. 665-86 [PMID:18452589] Nagano AJ,Fukao Y,Fujiwara M,Nishimura M,Hara-Nishimura I Antagonistic jacalin-related lectins regulate the size of ER body-type beta-glucosidase complexes in Arabidopsis thaliana. Plant Cell Physiol., 2008. 49(6): p. 969-80 [PMID:18467340] Abercrombie JM, et al. Transcriptional responses of Arabidopsis thaliana plants to As (V) stress. BMC Plant Biol., 2008. 8: p. 87 [PMID:18684332] Jakoby MJ, et al. Transcriptional profiling of mature Arabidopsis trichomes reveals that NOECK encodes the MIXTA-like transcriptional regulator MYB106. Plant Physiol., 2008. 148(3): p. 1583-602 [PMID:18805951] Khandelwal A,Elvitigala T,Ghosh B,Quatrano RS Arabidopsis transcriptome reveals control circuits regulating redox homeostasis and the role of an AP2 transcription factor. Plant Physiol., 2008. 148(4): p. 2050-8 [PMID:18829981] Huibers RP,de Jong M,Dekter RW,Van den Ackerveken G Disease-specific expression of host genes during downy mildew infection of Arabidopsis. Mol. Plant Microbe Interact., 2009. 22(9): p. 1104-15 [PMID:19656045] Pandey SP,Roccaro M,Sch Transcriptional reprogramming regulated by WRKY18 and WRKY40 facilitates powdery mildew infection of Arabidopsis. Plant J., 2010. 64(6): p. 912-23 [PMID:21143673] Ou B, et al. A high-throughput screening system for Arabidopsis transcription factors and its application to Med25-dependent transcriptional regulation. Mol Plant, 2011. 4(3): p. 546-55 [PMID:21343311] Mehterov N, et al. Oxidative stress provokes distinct transcriptional responses in the stress-tolerant atr7 and stress-sensitive loh2 Arabidopsis thaliana mutants as revealed by multi-parallel quantitative real-time PCR analysis of ROS marker and antioxidant genes. Plant Physiol. Biochem., 2012. 59: p. 20-9 [PMID:22710144] Etchells JP,Provost CM,Turner SR Plant vascular cell division is maintained by an interaction between PXY and ethylene signalling. PLoS Genet., 2012. 8(11): p. e1002997 [PMID:23166504] Schweizer F,Bodenhausen N,Lassueur S,Masclaux FG,Reymond P Differential Contribution of Transcription Factors to Arabidopsis thaliana Defense Against Spodoptera littoralis. Front Plant Sci, 2013. 4: p. 13 [PMID:23382734] Cai XT, et al. Arabidopsis ERF109 mediates cross-talk between jasmonic acid and auxin biosynthesis during lateral root formation. Nat Commun, 2014. 5: p. 5833 [PMID:25524530] Matsuo M, et al. High REDOX RESPONSIVE TRANSCRIPTION FACTOR1 Levels Result in Accumulation of Reactive Oxygen Species in Arabidopsis thaliana Shoots and Roots. Mol Plant, 2015. 8(8): p. 1253-73 [PMID:25882345] Matsuo M,Oelmüller R REDOX RESPONSIVE TRANSCRIPTION FACTOR1 is involved in age-dependent and systemic stress signaling. Plant Signal Behav, 2015. 10(11): p. e1051279 [PMID:26479402] Bertea CM,Narayana R,Agliassa C,Rodgers CT,Maffei ME Geomagnetic Field (Gmf) and Plant Evolution: Investigating the Effects of Gmf Reversal on Arabidopsis thaliana Development and Gene Expression. J Vis Exp, 2018. [PMID:26649488] Bahieldin A, et al. Ethylene responsive transcription factor ERF109 retards PCD and improves salt tolerance in plant. BMC Plant Biol., 2016. 16(1): p. 216 [PMID:27716054] Huang D,Lin W,Deng B,Ren Y,Miao Y Dual-Located WHIRLY1 Interacting with LHCA1 Alters Photochemical Activities of Photosystem I and Is Involved in Light Adaptation in Arabidopsis. Int J Mol Sci, 2018. [PMID:29112140] Kong X, et al. PHB3 Maintains Root Stem Cell Niche Identity through ROS-Responsive AP2/ERF Transcription Factors in Arabidopsis. Cell Rep, 2018. 22(5): p. 1350-1363 [PMID:29386120] Soliman ERS,Meyer P Responsiveness and Adaptation to Salt Stress of the REDOX-RESPONSIVE TRANSCRIPTION FACTOR 1 (RRTF1) Gene are Controlled by its Promoter. Mol. Biotechnol., 2019. 61(4): p. 254-260 [PMID:30734200]