PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G21610.1
Common NameF17L22.70, F18E5.230, LOL2
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family LSD
Protein Properties Length: 155aa    MW: 17248.4 Da    PI: 5.0375
Description lsd one like 2
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G21610.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD142.97.9e-146387125
      zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                 Cg+Cr lLsY rG+++V+C++C+tV
  AT4G21610.1 63 CGSCRRLLSYLRGSKHVKCSSCQTV 87
                 ************************9 PP
2zf-LSD143.74.5e-14101125125
      zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                  C++C+ lL+YP+GAp+VRC++C+ V
  AT4G21610.1 101 CNNCKLLLMYPYGAPAVRCSSCNSV 125
                  ***********************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010533.7E-186090IPR005735Zinc finger, LSD1-type
PfamPF069432.0E-106387IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010537.7E-1198126IPR005735Zinc finger, LSD1-type
PfamPF069432.4E-11101125IPR005735Zinc finger, LSD1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009617Biological Processresponse to bacterium
GO:0005634Cellular Componentnucleus
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000191anatomysynergid
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 155 aa     Download sequence    Send to blast
MEEIQQQTQK EEQKHREEEE EEEEGPPPGW ESAVLPPPIV TITAAVNPNP TTVEIPEKAQ  60
MVCGSCRRLL SYLRGSKHVK CSSCQTVNLV LEANQVGQVN CNNCKLLLMY PYGAPAVRCS  120
SCNSVTDISE NNKRPPWSEQ QGPLKSLSSL RRAEN
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.469792e-91flower
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible254423_at0.0
Expression AtlasAT4G21610-
AtGenExpressAT4G21610-
ATTED-IIAT4G21610-
Functional Description ? help Back to Top
Source Description
TAIRContains the same novel zinc finger motif with LSD1, a negative regulator of cell death and defense response. Due to differential splicing, it encodes two different proteins, one of which contains an additional, putative DNA binding motif. Northern analysis demonstrated that LOL2 transcripts containing the additional DNA binding motif are predominantly upregulated after treatment with both virulent and avirulent Pseudomonas syringae pv maculicola strains.
UniProtPutative zinc finger that may be involved in programmed cell death and defense response. {ECO:0000250}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G21610.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G21610
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0117600.0BT011760.1 Arabidopsis thaliana At4g21610 mRNA, complete cds.
GenBankBT0123840.0BT012384.1 Arabidopsis thaliana At4g21610 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_193892.11e-109lsd one like 2
SwissprotO654261e-110LOL2_ARATH; Protein LOL2
TrEMBLA0A178UWB71e-108A0A178UWB7_ARATH; LOL2
STRINGAT4G21610.11e-109(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM136112226
Representative plantOGRP11461753
Publications ? help Back to Top
  1. Ma L, et al.
    Genomic evidence for COP1 as a repressor of light-regulated gene expression and development in Arabidopsis.
    Plant Cell, 2002. 14(10): p. 2383-98
    [PMID:12368493]
  2. Epple P,Mack AA,Morris VR,Dangl JL
    Antagonistic control of oxidative stress-induced cell death in Arabidopsis by two related, plant-specific zinc finger proteins.
    Proc. Natl. Acad. Sci. U.S.A., 2003. 100(11): p. 6831-6
    [PMID:12732715]
  3. Guti
    Phylogenetic profiling of the Arabidopsis thaliana proteome: what proteins distinguish plants from other organisms?
    Genome Biol., 2004. 5(8): p. R53
    [PMID:15287975]
  4. Larkindale J,Vierling E
    Core genome responses involved in acclimation to high temperature.
    Plant Physiol., 2008. 146(2): p. 748-61
    [PMID:18055584]
  5. Tamaoki M,Freeman JL,Pilon-Smits EA
    Cooperative ethylene and jasmonic acid signaling regulates selenite resistance in Arabidopsis.
    Plant Physiol., 2008. 146(3): p. 1219-30
    [PMID:18178671]
  6. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  7. Wuest SE, et al.
    Arabidopsis female gametophyte gene expression map reveals similarities between plant and animal gametes.
    Curr. Biol., 2010. 20(6): p. 506-12
    [PMID:20226671]
  8. Bienvenut WV, et al.
    Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features.
    Mol. Cell Proteomics, 2012. 11(6): p. M111.015131
    [PMID:22223895]