PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G09180.1
Common NameBHLH81, EN72, FBH2, T8A17.70
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 262aa    MW: 28690.8 Da    PI: 4.6827
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G09180.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.51e-12196241655
                  HHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   6 nerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                  +++Er RR ri +++ +L+el+P+     +k  + a++Le+AveY+k Lq
  AT4G09180.1 196 SIAERVRRTRISDRIRKLQELVPNM----DKQTNTADMLEEAVEYVKVLQ 241
                  689*********************7....688***************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088814.557190240IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.83E-16193254IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.64E-12194245No hitNo description
Gene3DG3DSA:4.10.280.104.5E-16195252IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.6E-12196246IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000108.1E-10196241IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045944Biological Processpositive regulation of transcription from RNA polymerase II promoter
GO:0005634Cellular Componentnucleus
GO:0001046Molecular Functioncore promoter sequence-specific DNA binding
GO:0001228Molecular Functiontranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
Sequence ? help Back to Top
Protein Sequence    Length: 262 aa     Download sequence    Send to blast
MQPTSVGSSG GGDDGGGRGG GGGLSRSGLS RIRSAPATWL EALLEEDEEE SLKPNLGLTD  60
LLTGNSNDLP TSRGSFEFPI PVEQGLYQQG GFHRQNSTPA DFLSGSDGFI QSFGIQANYD  120
YLSGNIDVSP GSKRSREMEA LFSSPEFTSQ MKGEQSSGQV PTGVSSMSDM NMENLMEDSV  180
AFRVRAKRGC ATHPRSIAER VRRTRISDRI RKLQELVPNM DKQTNTADML EEAVEYVKVL  240
QRQIQELTEE QKRCTCIPKE EQ
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
11522GGRGGGGG
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.337100.0flower| seed
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1865116160.0
Expression AtlasAT4G09180-
AtGenExpressAT4G09180-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in flowers. {ECO:0000269|PubMed:12679534}.
Function -- GeneRIF ? help Back to Top
  1. There are four CONSTANS transcriptional activators FBH1-4 which are related basic helix-loop-helix-type transcription factors that preferentially bind to the E-box cis-elements in the CO promoter. Overexpression of all FBH genes drastically elevated CO levels and caused early flowering regardless of photoperiod. [FBH2]
    [PMID: 22334645]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G09180.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G09180
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2303840.0AK230384.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor, complete cds, clone: RAFL24-31-D13.
GenBankBT0104230.0BT010423.1 Arabidopsis thaliana At4g09180 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_192657.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ9M0R00.0BH081_ARATH; Transcription factor bHLH81
TrEMBLA0A178UYK30.0A0A178UYK3_ARATH; FBH2
STRINGAT4G09180.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM51042551
Representative plantOGRP5111580
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Zhao J, et al.
    Analysis of gene expression profiles in response to Sclerotinia sclerotiorum in Brassica napus.
    Planta, 2007. 227(1): p. 13-24
    [PMID:17665211]
  7. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  8. Ito S, et al.
    FLOWERING BHLH transcriptional activators control expression of the photoperiodic flowering regulator CONSTANS in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2012. 109(9): p. 3582-7
    [PMID:22334645]
  9. Vidal EA, et al.
    Integrated RNA-seq and sRNA-seq analysis identifies novel nitrate-responsive genes in Arabidopsis thaliana roots.
    BMC Genomics, 2013. 14: p. 701
    [PMID:24119003]
  10. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]