PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT4G06634.3

Common Name

AtYY1, YY1

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

C2H2

Protein Properties

Length: 380aa MW: 44014.6 Da PI: 6.2074

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT4G06634.3	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	10.8	0.0016	70	92	3	23
ET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 3 Cp..dCgksFsrksnLkrHirtH 23 C+ Cgk+F + s L++H H AT4G06634.3 70 CSydGCGKTFFDVSALRKHSHIH 92 78889**************7766 PP
2	zf-C2H2	17	1.6e-05	97	121	1	23
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 y+C Cgk F ++s LkrH H AT4G06634.3 97 YVCDqeGCGKKFLDSSKLKRHYLIH 121 99*******************9988 PP
3	zf-C2H2	11.6	0.00084	127	155	1	23
EEET..TTT....EEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCg....ksFsrksnLkrHirtH 23 y C+ Cg + Fs nL++H++tH AT4G06634.3 127 YICTyeGCGklwmQAFSLDFNLRSHMKTH 155 8899999*********************9 PP
4	zf-C2H2	13	0.00032	223	248	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 y Cp C k + + + Lk H+++ H AT4G06634.3 223 YACPyeGCEKAYIHEYKLKLHLKReH 248 89*********************999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	3.7E-14	63	94	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.23E-5	63	93	No hit	No description
SMART	SM00355	0.0053	68	92	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	68	97	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	70	92	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.69E-11	84	135	No hit	No description
Gene3D	G3DSA:3.30.160.60	4.8E-14	95	119	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.0011	97	121	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	14.274	97	126	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	99	121	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	3.3E-18	120	152	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	1	127	155	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	5.03E-7	141	187	No hit	No description
Gene3D	G3DSA:3.30.160.60	4.6E-9	153	183	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.12	161	186	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	163	186	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.31E-5	218	246	No hit	No description
Gene3D	G3DSA:3.30.160.60	6.6E-9	219	245	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.012	223	248	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.328	223	253	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	225	248	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000293	anatomy	guard cell

Sequence ? help Back to Top
Protein Sequence Length: 380 aa Download sequence Send to blast
MDHQNYQYQN PFERRPILKS KAPAVKWIKE WVPQDIVATE DTFSRLKEKE KEPDVPEPEP 60 EPTTEILFLC SYDGCGKTFF DVSALRKHSH IHGERQYVCD QEGCGKKFLD SSKLKRHYLI 120 HTGERNYICT YEGCGKLWMQ AFSLDFNLRS HMKTHSQENY HICPYSGCVK RYAHEYKLKN 180 HVAAYHEKNG GGETPKYTPP AEKVLRTVKT PATVCGPSSD RPYACPYEGC EKAYIHEYKL 240 KLHLKREHPG HLQEENADTP TLNKHNGNDR NEIDDGSDQD VYRKHASNGK GQTHKQQSRA 300 KPNMRTPPAK VGKKGSTSSP AKARIAKKPW QAKETFEEVE REEEEDSEET EEDRDNVEDG 360 WRFGENNEDD DDDEETEYED

Sequence ? help Back to Top

Protein Sequence Length: 380 aa Download sequence Send to blast

MDHQNYQYQN PFERRPILKS KAPAVKWIKE WVPQDIVATE DTFSRLKEKE KEPDVPEPEP  60
EPTTEILFLC SYDGCGKTFF DVSALRKHSH IHGERQYVCD QEGCGKKFLD SSKLKRHYLI  120
HTGERNYICT YEGCGKLWMQ AFSLDFNLRS HMKTHSQENY HICPYSGCVK RYAHEYKLKN  180
HVAAYHEKNG GGETPKYTPP AEKVLRTVKT PATVCGPSSD RPYACPYEGC EKAYIHEYKL  240
KLHLKREHPG HLQEENADTP TLNKHNGNDR NEIDDGSDQD VYRKHASNGK GQTHKQQSRA  300
KPNMRTPPAK VGKKGSTSSP AKARIAKKPW QAKETFEEVE REEEEDSEET EEDRDNVEDG  360
WRFGENNEDD DDDEETEYED

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ubd_C	9e-35	70	185	8	117	PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.47264	0.0	inflorescence\| silique

Expression -- Microarray ? help Back to Top
Source	ID
Expression Atlas	AT4G06634
AtGenExpress	AT4G06634

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269\|PubMed:26961720}.
Uniprot	TISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269\|PubMed:26961720}.

Functional Description ? help Back to Top
Source	Description
UniProt	Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269\|PubMed:22508367, ECO:0000269\|PubMed:24451981, ECO:0000269\|PubMed:26961720}.

Function -- GeneRIF ? help Back to Top
genome-wide target gene analysis revealed that AtYY1 was involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism, and stress response[AtYY1] [PMID: 22508367]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT4G06634.3

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269\|PubMed:26961720}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT4G06634

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB073162	0.0	AB073162.1 Arabidopsis thaliana DNA, chromosome 4 centromere region, BAC clone:F8H12.
GenBank	CP002687	0.0	CP002687.1 Arabidopsis thaliana chromosome 4 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001190684.1	0.0	zinc finger (C2H2 type) family protein
Swissprot	Q2V3L3	0.0	YY1_ARATH; Zinc finger transcription factor YY1
TrEMBL	F4JGT7	0.0	F4JGT7_ARATH; Zinc finger (C2H2 type) family protein
STRING	AT4G06634.1	0.0	(Arabidopsis thaliana)

Link Out ? help Back to Top
Phytozome	AT4G06634.3
Entrez Gene	826093
iHOP	AT4G06634
wikigenes	AT4G06634

Publications ? help Back to Top
Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4. DNA Res., 2001. 8(6): p. 285-90 [PMID:11853315] Reiland S, et al. Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks. Plant Physiol., 2009. 150(2): p. 889-903 [PMID:19376835] Rehrauer H, et al. AGRONOMICS1: a new resource for Arabidopsis transcriptome profiling. Plant Physiol., 2010. 152(2): p. 487-99 [PMID:20032078] Wu X,Cheng Y,Li T,Wang Z,Liu JY In vitro identification of DNA-binding motif for the new zinc finger protein AtYY1. Acta Biochim. Biophys. Sin. (Shanghai), 2012. 44(6): p. 483-9 [PMID:22508367] Lai Z, et al. MED18 interaction with distinct transcription factors regulates multiple plant functions. Nat Commun, 2014. 5: p. 3064 [PMID:24451981] Bieluszewski T, et al. AtEAF1 is a potential platform protein for Arabidopsis NuA4 acetyltransferase complex. BMC Plant Biol., 2015. 15: p. 75 [PMID:25849764] Li T,Wu XY,Li H,Song JH,Liu JY A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network. Mol Plant, 2016. 9(5): p. 650-661 [PMID:26961720] Wu XY,Li T A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response. Front Plant Sci, 2017. 8: p. 323 [PMID:28348572]