PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G02640.2
Common NameATBZIP10, BZIP10, BZO2H1, T10P11.9
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bZIP
Protein Properties Length: 417aa    MW: 45944.8 Da    PI: 5.0999
Description bZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G02640.2genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_147.83.2e-15221275357
                  XXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       bZIP_1   3 elkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkeva 57 
                  ++k+ rr+ +NRe+ArrsR+RK++++  Le+ v  L++e ++L k+l++++ +++
  AT4G02640.2 221 DVKKSRRMLSNRESARRSRRRKQEQTSDLETQVNDLKGEHSSLLKQLSNMNHKYD 275
                  789*****************************************99999888776 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003386.6E-20219283IPR004827Basic-leucine zipper domain
PfamPF001702.2E-14221275IPR004827Basic-leucine zipper domain
PROSITE profilePS5021711.116221276IPR004827Basic-leucine zipper domain
SuperFamilySSF579598.44E-12222274No hitNo description
Gene3DG3DSA:1.20.5.1708.3E-13223274No hitNo description
PROSITE patternPS000360226241IPR004827Basic-leucine zipper domain
PfamPF124988.6E-12290351IPR020983Basic leucine-zipper, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0002240Biological Processresponse to molecule of oomycetes origin
GO:0009626Biological Processplant-type hypersensitive response
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000693Biological Processpositive regulation of seed maturation
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0045735Molecular Functionnutrient reservoir activity
GO:0046982Molecular Functionprotein heterodimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001017developmental stageM germinated pollen stage
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 417 aa     Download sequence    Send to blast
MNSIFSIDDF SDPFWETPPI PLNPDSSKPV TADEVSQSQP EWTFEMFLEE ISSSAVSSEP  60
LGNNNNAIVG VSSAQSLPSV SGQNDFEDDS RFRDRDSGNL DCAAPMTTKT VIVDSDDYRR  120
VLKNKLETEC ATVVSLRVGS VKPEDSTSSP ETQLQPVQSS PLTQGSLMTP GELGVTSSLP  180
AEVKKTGVSM KQVTSGSSRE YSDDEDLDEE NETTGSLKPE DVKKSRRMLS NRESARRSRR  240
RKQEQTSDLE TQVNDLKGEH SSLLKQLSNM NHKYDEAAVG NRILKADIET LRAKVKMAEE  300
TVKRVTGMNP MLLGRSSGHN NNNRMPITGN NRMDSSSIIP AYQPHSNLNH MSNQNIGIPT  360
ILPPRLGNNF AAPPSQTSSP LQRIRNGQNH HVTPSANPYG WNTEPQNDSA WPKKCVD
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1235242RRSRRRKQ
2237242SRRRKQ
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.251760.0flower| inflorescence| root| seed| silique
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible255496_at0.0
Expression AtlasAT4G02640-
AtGenExpressAT4G02640-
ATTED-IIAT4G02640-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: First observed in carpels and seeds at early stages of development, mostly in embryo and, at lower extent, in the endosperm. Accumulates and peaks at maturation. Fade out during late seed development steps, restricted to the inner layer of the seed coat, and, at very low levels, in the mature embryo and the remaining endosperm. Also present in the lignified inner subepidermal layer of the valves. In the anthers, restricted to the connective tissue at pre- and post-dehiscence stages and detected in the vascular tissue of the stamen filament. {ECO:0000269|PubMed:12657652, ECO:0000269|PubMed:18841482}.
UniprotTISSUE SPECIFICITY: Expressed in roots, shoots, stems, young leaves, trichomes, hydathodes, siliques, seeds, and flowers, mostly in vascular tissues. {ECO:0000269|PubMed:12657652, ECO:0000269|PubMed:18841482}.
Functional Description ? help Back to Top
Source Description
TAIREncodes a basic leucine zipper (bZIP) transcription factor AtbZIP10. AtbZIP10 shuttles between the nucleus and the cytoplasm. It binds consensus G- and C-box DNA sequences. AtbZIP10 acts antagonistically with LSD1 in both pathogen-induced hypersensitive response and basal defense responses.
UniProtTranscription factor that binds to the C-box-like motif (5'-TGCTGACGTCA-3') and G-box-like motif (5'-CCACGTGGCC-3'), ABRE elements, of gene promoters. Binds to the 5'-ACGT-3' motif of seed storage protein (SSP) encoding gene promoters (e.g. At2S and CRU3) and promotes their expression in seeds when in complex with ABI3 and BZIP53. Involved in the defense responses to the biotrophic pathogen Hyaloperonospora parasitica and oxidative stress responses; mediates positively cell death (PubMed:12657652, PubMed:16957775, PubMed:19261733, PubMed:19531597). Promotes BZIP53-mediated response to hypoosmolarity stress that leads to POX1/PRODH1 accumulation (PubMed:16810321). {ECO:0000269|PubMed:12657652, ECO:0000269|PubMed:16810321, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:19261733, ECO:0000269|PubMed:19531597}.
Function -- GeneRIF ? help Back to Top
  1. Data show that AtbZIP1 can bind ACGT-based motifs in vitro and that the binding characteristics appear to be affected by the heterodimerization between AtbZIP1 and the C-group AtbZIPs, including AtbZIP10 and AtbZIP63.
    [PMID: 20080816]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G02640.2
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT4G34590, AT5G24800, AT5G28770, AT5G49450, AT5G58080, AT1G75390
IntActSearch O22763
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G02640
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF3102220.0AF310222.1 Arabidopsis thaliana bZIP protein BZO2H1 mRNA, complete cds, alternatively spliced.
GenBankBT0255580.0BT025558.1 Arabidopsis thaliana At4g02640 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_849290.10.0bZIP transcription factor family protein
SwissprotO227630.0BZP10_ARATH; Basic leucine zipper 10
TrEMBLA0A178V4D90.0A0A178V4D9_ARATH; BZO2H1
STRINGAT4G02640.20.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM148711720
Representative plantOGRP18391639
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Jakoby M, et al.
    bZIP transcription factors in Arabidopsis.
    Trends Plant Sci., 2002. 7(3): p. 106-11
    [PMID:11906833]
  3. Vincentz M,Bandeira-Kobarg C,Gauer L,Schl
    Evolutionary pattern of angiosperm bZIP factors homologous to the maize Opaque2 regulatory protein.
    J. Mol. Evol., 2003. 56(1): p. 105-16
    [PMID:12569427]
  4. Lara P, et al.
    Synergistic activation of seed storage protein gene expression in Arabidopsis by ABI3 and two bZIPs related to OPAQUE2.
    J. Biol. Chem., 2003. 278(23): p. 21003-11
    [PMID:12657652]
  5. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  6. Ehlert A, et al.
    Two-hybrid protein-protein interaction analysis in Arabidopsis protoplasts: establishment of a heterodimerization map of group C and group S bZIP transcription factors.
    Plant J., 2006. 46(5): p. 890-900
    [PMID:16709202]
  7. Weltmeier F, et al.
    Combinatorial control of Arabidopsis proline dehydrogenase transcription by specific heterodimerisation of bZIP transcription factors.
    EMBO J., 2006. 25(13): p. 3133-43
    [PMID:16810321]
  8. Kaminaka H, et al.
    bZIP10-LSD1 antagonism modulates basal defense and cell death in Arabidopsis following infection.
    EMBO J., 2006. 25(18): p. 4400-11
    [PMID:16957775]
  9. Popescu SC, et al.
    Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays.
    Proc. Natl. Acad. Sci. U.S.A., 2007. 104(11): p. 4730-5
    [PMID:17360592]
  10. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  11. Weltmeier F, et al.
    Expression patterns within the Arabidopsis C/S1 bZIP transcription factor network: availability of heterodimerization partners controls gene expression during stress response and development.
    Plant Mol. Biol., 2009. 69(1-2): p. 107-19
    [PMID:18841482]
  12. Roschzttardtz H, et al.
    A nuclear gene encoding the iron-sulfur subunit of mitochondrial complex II is regulated by B3 domain transcription factors during seed development in Arabidopsis.
    Plant Physiol., 2009. 150(1): p. 84-95
    [PMID:19261733]
  13. Alonso R, et al.
    A pivotal role of the basic leucine zipper transcription factor bZIP53 in the regulation of Arabidopsis seed maturation gene expression based on heterodimerization and protein complex formation.
    Plant Cell, 2009. 21(6): p. 1747-61
    [PMID:19531597]
  14. Kang SG,Price J,Lin PC,Hong JC,Jang JC
    The arabidopsis bZIP1 transcription factor is involved in sugar signaling, protein networking, and DNA binding.
    Mol Plant, 2010. 3(2): p. 361-73
    [PMID:20080816]
  15. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  16. Song QX, et al.
    Soybean GmbZIP123 gene enhances lipid content in the seeds of transgenic Arabidopsis plants.
    J. Exp. Bot., 2013. 64(14): p. 4329-41
    [PMID:23963672]
  17. Veerabagu M, et al.
    The interaction of the Arabidopsis response regulator ARR18 with bZIP63 mediates the regulation of PROLINE DEHYDROGENASE expression.
    Mol Plant, 2014. 7(10): p. 1560-77
    [PMID:24948556]
  18. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  19. Pedrotti L, et al.
    Snf1-RELATED KINASE1-Controlled C/S1-bZIP Signaling Activates Alternative Mitochondrial Metabolic Pathways to Ensure Plant Survival in Extended Darkness.
    Plant Cell, 2018. 30(2): p. 495-509
    [PMID:29348240]