PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G01460.1
Common NameBHLH57, EN12, F11O4.13
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 315aa    MW: 35306.9 Da    PI: 6.2691
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G01460.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH44.92.2e-14113164155
                  CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                  +r++h ++Er+RR+++N+ ++ Lr+l+P++     ++ + a+i+  A+++Ik+L+
  AT4G01460.1 113 QRMTHIAVERNRRRQMNEHLNSLRSLMPPS---FLQRGDQASIVGGAIDFIKELE 164
                  79***************************9...89*****************996 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474591.44E-16111180IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.1E-13111168IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000835.76E-13111168No hitNo description
PROSITE profilePS5088815.72112163IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000107.5E-12113164IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.4E-11118169IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020038anatomypetiole
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 315 aa     Download sequence    Send to blast
MSGLMSFGEL EDQFGQISDT TMEEKIPFLQ MLQCIEHPFT TTEPNQFLQS LLQIQTLESK  60
SCLTLETNIK RDPGQTDDPE KDPRTENGAV TVKEKRKRKR TRAPKNKDEV ENQRMTHIAV  120
ERNRRRQMNE HLNSLRSLMP PSFLQRGDQA SIVGGAIDFI KELEQLLQSL EAEKRKDGTD  180
ETPKTASCSS SSSLACTNSS ISSVSTTSEN GFTARFGGGD TTEVEATVIQ NHVSLKVRCK  240
RGKRQILKAI VSIEELKLAI LHLTISSSFD FVIYSFNLKM EDGCKLGSAD EIATAVHQIF  300
EQINGEVMWS NLSRT
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1113124RMTHIAVERNRR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.344250.0inflorescence
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1865114310.0
Genevisible255579_at0.0
Expression AtlasAT4G01460-
AtGenExpressAT4G01460-
ATTED-IIAT4G01460-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed constitutively in leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G01460.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by heat treatment. {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G01460
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0997800.0AY099780.1 Arabidopsis thaliana putative bHLH DNA-binding protein (At4g01460) mRNA, complete cds.
GenBankAY1288810.0AY128881.1 Arabidopsis thaliana putative bHLH DNA-binding protein (At4g01460) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001329264.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
RefseqNP_192055.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ9M1280.0BH057_ARATH; Transcription factor bHLH57
TrEMBLA0A178UZ310.0A0A178UZ31_ARATH; Uncharacterized protein
STRINGAT4G01460.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM146961721
Representative plantOGRP25315131
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
    Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes.
    Plant J., 2004. 38(2): p. 366-79
    [PMID:15078338]
  6. Scheible WR, et al.
    Genome-wide reprogramming of primary and secondary metabolism, protein synthesis, cellular growth processes, and the regulatory infrastructure of Arabidopsis in response to nitrogen.
    Plant Physiol., 2004. 136(1): p. 2483-99
    [PMID:15375205]
  7. Oono Y, et al.
    Monitoring expression profiles of Arabidopsis genes during cold acclimation and deacclimation using DNA microarrays.
    Funct. Integr. Genomics, 2006. 6(3): p. 212-34
    [PMID:16463051]
  8. Cao D,Cheng H,Wu W,Soo HM,Peng J
    Gibberellin mobilizes distinct DELLA-dependent transcriptomes to regulate seed germination and floral development in Arabidopsis.
    Plant Physiol., 2006. 142(2): p. 509-25
    [PMID:16920880]
  9. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  10. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  11. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  12. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]