PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G00250.1
Common NameA_IG005I10.12, F5I10.12
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family GeBP
Protein Properties Length: 319aa    MW: 35513.3 Da    PI: 9.4264
Description DNA-binding storekeeper protein-related transcriptional regulator
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G00250.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1DUF573108.16.4e-34114204298
       DUF573   2 lfqrlwseeDeivlLqGlidfkaktgkspsddidafyefvkksisfkvsksqlveKirrLKkKfkkkvkkaksgkepsfskehdqkifelskkiWgs 98 
                  ++qr+wseeDei+lLq++idfka+tg+sp+d+ +af++++kksisf+vs+ q+++KirrLK+K+  ++k+      +s +++hd+k+++l+  iWgs
  AT4G00250.1 114 NPQRVWSEEDEISLLQAVIDFKAETGTSPWDHKNAFFDIAKKSISFDVSHVQFFDKIRRLKNKYFVNRKN------KSGESNHDKKCLGLAVLIWGS 204
                  68******************************************************************99......667789*************95 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF045041.0E-24116203IPR007592Protein of unknown function DUF573
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010629Biological Processnegative regulation of gene expression
GO:0071333Biological Processcellular response to glucose stimulus
GO:0005623Cellular Componentcell
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 319 aa     Download sequence    Send to blast
MAPLESPATA SSSEVESSSE EIFKSSSEES KPKDPVTVPS SKTLKSPSAA VNSKTDSSDD  60
SEKQSFVLTR RKKKEGAAES PAVKSGKKRA GEGSTSRDMH VKRVKKEDDN KKANPQRVWS  120
EEDEISLLQA VIDFKAETGT SPWDHKNAFF DIAKKSISFD VSHVQFFDKI RRLKNKYFVN  180
RKNKSGESNH DKKCLGLAVL IWGSDGMNVE SPVKKDESIL VKGKANSKEK KVEKPLVIED  240
EQVILGADSE WFEESFLVPV IANLGLDEYS VKKKWSKVSL ETKKKIQEKM KVVDAKKCEL  300
LLAEMDVLKD VTSVLAQTN
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
16974RRKKKE
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.345820.0seed
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible255668_s_at1e-161
Expression AtlasAT4G00250-
AtGenExpressAT4G00250-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed strongly in leaves and flowers, weakly in roots, and very weakly in stems. {ECO:0000269|PubMed:27031427}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription repressor that binds DNA in a sequence-specific manner, 5'-GCCT-3', to regulate the expression of PGR. Acts as a modulatory component for the glucose-triggered developmental leaf growth process. {ECO:0000269|PubMed:27031427}.
Function -- GeneRIF ? help Back to Top
  1. AtSTKL1 and AtSTKL2 function both as repressors of AtPGR transcription and as novel transcription factors in the Glc signaling pathway.[AtSTKL2]
    [PMID: 27031427]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00420DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G00250.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon glucose treatment. {ECO:0000269|PubMed:27031427}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G00250
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAL1614710.0AL161471.2 Arabidopsis thaliana DNA chromosome 4, contig fragment No. 1.
GenBankBT0039610.0BT003961.1 Arabidopsis thaliana clone RAFL15-21-E22 (R20787) unknown protein (At4g00250) mRNA, complete cds.
GenBankBT0056660.0BT005666.1 Arabidopsis thaliana clone U20787 unknown protein (At4g00250) mRNA, complete cds.
GenBankCP0026870.0CP002687.1 Arabidopsis thaliana chromosome 4 sequence.
GenBankF5I100.0AF195115.1 Arabidopsis thaliana BAC F5I10.
GenBankIG005I100.0AF013293.1 Arabidopsis thaliana BAC IG005I10.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_567161.10.0DNA-binding storekeeper protein-related transcriptional regulator
SwissprotO230770.0STKLN_ARATH; Transcription factor STKL2
TrEMBLA0A178UZP91e-151A0A178UZP9_ARATH; Uncharacterized protein
STRINGAT4G00250.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM31328181
Representative plantOGRP4222523
Publications ? help Back to Top
  1. Curaba J,Herzog M,Vachon G
    GeBP, the first member of a new gene family in Arabidopsis, encodes a nuclear protein with DNA-binding activity and is regulated by KNAT1.
    Plant J., 2003. 33(2): p. 305-17
    [PMID:12535344]
  2. Dal Bosco C, et al.
    Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.
    J. Biol. Chem., 2004. 279(2): p. 1060-9
    [PMID:14576160]
  3. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  4. Hanada K, et al.
    Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
    Mol. Biol. Evol., 2011. 28(1): p. 377-82
    [PMID:20736450]
  5. Chung MS, et al.
    Regulation of Arabidopsis thaliana plasma membrane glucose-responsive regulator (AtPGR) expression by A. thaliana storekeeper-like transcription factor, AtSTKL, modulates glucose response in Arabidopsis.
    Plant Physiol. Biochem., 2016. 104: p. 155-64
    [PMID:27031427]
  6. Khare D, et al.
    Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana.
    New Phytol., 2017. 213(3): p. 1257-1273
    [PMID:27768815]