PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT3G61950.2

Common Name

BHLH67, EN11, F21F14.120

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 307aa MW: 35040.6 Da PI: 7.7201

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT3G61950.2	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	43.2	7.2e-14	125	175	1	54
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +r +h ++Er+RR+++N+ ++ Lr llP++ + ++ + a+i+ A++Y+k L AT3G61950.2 125 QRINHIAVERNRRRQMNEHINSLRALLPPS---YIQRGDQASIVGGAINYVKVL 175 699*************************...9**************9977 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	4.71E-17	123	194	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	4.92E-11	123	180	No hit	No description
PROSITE profile	PS50888	15.51	124	175	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.5E-11	125	175	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	8.9E-14	126	193	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.1E-10	130	181	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009052	anatomy	flower pedicel
PO:0020038	anatomy	petiole
PO:0025022	anatomy	collective leaf structure
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 307 aa Download sequence Send to blast
MLQSEDPSSF FSIKEPNFLT LLSLQTLKEP WELERYLSLE DSQFHSPVQS ETNRFMEGAN 60 QAVSSQEIPF SQANMTLPSS TSSPLSAHSR RKRKINHLLP QEMTREKRKR RKTKPSKNNE 120 EIENQRINHI AVERNRRRQM NEHINSLRAL LPPSYIQRGD QASIVGGAIN YVKVLEQIIQ 180 SLESQKRTQQ QSNSEVVENA LNHLSGISSN DLWTTLEDQT CIPKIEATVI QNHVSLKVQC 240 EKKQGQLLKG IISLEKLKLT VLHLNITTSS HSSVSYSFNL KMEDECDLES ADEITAAVHR 300 IFDIPTI

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	91	111	KRKINHLLPQEMTREKRKRRK
2	106	111	KRKRRK

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.22308	0.0	bud

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	251299_at	0.0
Expression Atlas	AT3G61950	-
AtGenExpress	AT3G61950	-
ATTED-II	AT3G61950	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269\|PubMed:12679534}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT3G61950.2

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT5G51780
IntAct	Search Q700E4

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT3G61950

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ630481	0.0	AJ630481.1 Arabidopsis thaliana mRNA for hypothetical protein, clone At3g61950.
GenBank	AK118527	0.0	AK118527.1 Arabidopsis thaliana At3g61950 mRNA for putative bHLH transcription factor (bHLH067), complete cds, clone: RAFL19-75-M14.
GenBank	BT005298	0.0	BT005298.1 Arabidopsis thaliana At3g61950 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_850735.1	0.0	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Swissprot	Q700E4	0.0	BH067_ARATH; Transcription factor bHLH67
TrEMBL	A0A178VAG1	0.0	A0A178VAG1_ARATH; Uncharacterized protein
STRING	AT3G61950.1	0.0	(Arabidopsis thaliana)

Link Out ? help Back to Top
Phytozome	AT3G61950.2
Entrez Gene	825368
iHOP	AT3G61950
wikigenes	AT3G61950

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Seki M, et al. Functional annotation of a full-length Arabidopsis cDNA collection. Science, 2002. 296(5565): p. 141-5 [PMID:11910074] Heim MA, et al. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol., 2003. 20(5): p. 735-47 [PMID:12679534] Toledo-Ortiz G,Huq E,Quail PH The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell, 2003. 15(8): p. 1749-70 [PMID:12897250] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Bailey PC, et al. Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana. Plant Cell, 2003. 15(11): p. 2497-502 [PMID:14600211] Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes. Plant J., 2004. 38(2): p. 366-79 [PMID:15078338] Gong W, et al. Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes. Plant Physiol., 2004. 135(2): p. 773-82 [PMID:15208423] Ditt RF, et al. The Arabidopsis thaliana transcriptome in response to Agrobacterium tumefaciens. Mol. Plant Microbe Interact., 2006. 19(6): p. 665-81 [PMID:16776300] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Arabidopsis Interactome Mapping Consortium Evidence for network evolution in an Arabidopsis interactome map. Science, 2011. 333(6042): p. 601-7 [PMID:21798944] Efroni I, et al. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev. Cell, 2013. 24(4): p. 438-45 [PMID:23449474] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Yu H,Murchie EH,González-Carranza ZH,Pyke KA,Roberts JA Decreased photosynthesis in the erect panicle 3 (ep3) mutant of rice is associated with reduced stomatal conductance and attenuated guard cell development. J. Exp. Bot., 2015. 66(5): p. 1543-52 [PMID:25582452]