PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT3G56400.1

Common Name

ATWRKY70, T5P19.50, WRKY70

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

WRKY

Protein Properties

Length: 294aa MW: 32935.6 Da PI: 6.2319

Description

WRKY DNA-binding protein 70

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT3G56400.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	84.1	1.3e-26	120	180	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 +D ++WrKYGqKe+ +++fprsY+rCt++ gC+++k+v++ + +pk++ itY g+H+++ AT3G56400.1 120 EDAFSWRKYGQKEILNAKFPRSYFRCTHKytqGCKATKQVQKVELEPKMFSITYIGNHTCN 180 8*************************99999************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	4.5E-26	106	180	IPR003657	WRKY domain
PROSITE profile	PS50811	20.656	114	182	IPR003657	WRKY domain
SuperFamily	SSF118290	1.31E-23	114	181	IPR003657	WRKY domain
SMART	SM00774	1.2E-37	119	181	IPR003657	WRKY domain
Pfam	PF03106	2.3E-24	120	179	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009862	Biological Process	systemic acquired resistance, salicylic acid mediated signaling pathway
GO:0009864	Biological Process	induced systemic resistance, jasmonic acid mediated signaling pathway
GO:0010200	Biological Process	response to chitin
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0050832	Biological Process	defense response to fungus
GO:1900056	Biological Process	negative regulation of leaf senescence
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0005515	Molecular Function	protein binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025281	anatomy	pollen
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 294 aa Download sequence Send to blast
MDTNKAKKLK VMNQLVEGHD LTTQLQQLLS QPGSGLEDLV AKILVCFNNT ISVLDTFEPI 60 SSSSSLAAVE GSQNASCDND GKFEDSGDSR KRLGPVKGKR GCYKRKKRSE TCTIESTILE 120 DAFSWRKYGQ KEILNAKFPR SYFRCTHKYT QGCKATKQVQ KVELEPKMFS ITYIGNHTCN 180 TNAETPKSKT CDHHDEIFMD SEDHKSPSLS TSMKEEDNPH RHHGSSTEND LSLVWPEMVF 240 EEDYHHQASY VNGKTSTSID VLGSQDLMVF GGGGDFEFSE NEHFSIFSSC SNLS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6ir8_A	2e-20	119	179	8	68	OsWRKY45
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	89	107	RKRLGPVKGKRGCYKRKKR

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.5242	0.0	leaf\| root\| seed

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	14532617	0.0
Genevisible	251705_at	0.0
Expression Atlas	AT3G56400	-
AtGenExpress	AT3G56400	-
ATTED-II	AT3G56400	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: In flowers, first observed in both stigmatic papillae and the flower abscission zone, later confined to the abscission zone (PubMed:17310369). In leaves, level increases gradually up to the point of leaf senescence (PubMed:17310369, PubMed:22268143). {ECO:0000269\|PubMed:17310369, ECO:0000269\|PubMed:22268143}.
Uniprot	TISSUE SPECIFICITY: Expressed in leaves and flowers. {ECO:0000269\|PubMed:17310369, ECO:0000269\|PubMed:22268143}.

Functional Description ? help Back to Top
Source	Description
TAIR	member of WRKY Transcription Factor; Group III. Function as activator of SA-dependent defense genes and a repressor of JA-regulated genes. WRKY70-controlled suppression of JA-signaling is partly executed by NPR1.
UniProt	Transcription factor involved in senescence, biotic and abiotic stress responses by modulating various phytohormones signaling pathways (PubMed:14742872, PubMed:16623907, PubMed:17310369, PubMed:28576847). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Binds to the 5'-[CT]GACTTTT-3' motif in promoters of target genes to induce their expression (PubMed:24104863). Plays an important but not indispensable role in jasmonate and salicylic acid signaling (PubMed:18713432). Regulates positively the salicylic acid (SA)-mediated signal pathway, but negatively the jasmonic acid (JA)-mediated signal pathway, thus determining the balance between these mutually antagonistic pathways (PubMed:14742872, PubMed:16623907, PubMed:18713432, PubMed:28837631). Together with WRKY46, WRKY53 and WRKY54, prevents defense response to the necrotrophic pathogens P.carotovorum and B.cinerea, but promotes defense responses (including SA-induced pathogenesis-related (PR) genes expression) against biotrophic/hemibiotrophic SA-monitored pathogens (e.g. P.syringae, E.carotovora subsp. carotovora SCC3193 and E.cichoracearum), probably by regulating negatively the JA/ET and positively the SA signaling pathways (PubMed:28837631, PubMed:16623907, PubMed:22325892). Contributes to the suppression of jasmonic acid (MeJA)-induced expression of JA-responsive genes (e.g. PDF1.2) (PubMed:22325892, PubMed:16623907). Promotes susceptibility to JA-monitored pathogens (e.g. A.brassicicola), probably by facilitating SA-controlled suppression of JA-mediated defense. Represses the biosynthesis of the phytoalexin camalexin and indol-3-ylmethyl glucosinolate (IGS) (PubMed:16623907). Represses both SA and JA/ethylene (ET) mediated defense marker genes expression (PubMed:17310369). Negative regulator of SA biosynthesis (PubMed:28837631). Negative regulator of EDS1-dependent defense against E.amylovora (PubMed:22316300). Required for RPP4-mediated disease resistance and basal defense against H.parasitica, probably via late up-regulation (LURP) of resistance genes (e.g. CML10/CaBP22 and LURP1) (PubMed:17313163). Probably involved in defense responses toward insects (e.g. P.xylostella and B.brassicae) (PubMed:25339349). Together with WRKY54, negative regulator of developmental senescence, probably via the regulation of several senescence-associated markers genes (PubMed:17310369, PubMed:22268143). Together with WRKY46 and WRKY54, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression (PubMed:28576847). In collaboration with WRKY54, prevents stomatal closure and, consequently, osmotic stress tolerance (PubMed:23815736). Regulates rhizobacterium B.cereus AR156-induced systemic resistance (ISR) to P.syringae pv. tomato DC3000 (PubMed:26433201). {ECO:0000250\|UniProtKB:Q9SUP6, ECO:0000269\|PubMed:14742872, ECO:0000269\|PubMed:16623907, ECO:0000269\|PubMed:17310369, ECO:0000269\|PubMed:17313163, ECO:0000269\|PubMed:18713432, ECO:0000269\|PubMed:22268143, ECO:0000269\|PubMed:22316300, ECO:0000269\|PubMed:22325892, ECO:0000269\|PubMed:23815736, ECO:0000269\|PubMed:24104863, ECO:0000269\|PubMed:25339349, ECO:0000269\|PubMed:26433201, ECO:0000269\|PubMed:28576847, ECO:0000269\|PubMed:28837631, ECO:0000303\|PubMed:28837631}.

Function -- GeneRIF ? help Back to Top
WRKY70 has a pivotal role in determining the balance between SA-dependent and JA-dependent defense pathways. [PMID: 16623907] To expand understanding on how transcriptional control coordinates leaf senescence, AtWRKY70, a gene encoding a WRKY transcription factor that functions as a negative regulator of developmental senescence was characterized. [PMID: 17310369] The inactivation of the WRKY70 gene in wrky70-1 mutant does not alter the responses of both jasmonic acid (JA) and salicylic acid (SA), and that wrky70 mutation is unable to restore the coi1 mutant in JA responses. [PMID: 18713432] WRKY70 is required for snc2-1D-mediated resistance. [PMID: 20841424] WRKY54 and WRKY70 are negative regulators of leaf senescence. [PMID: 22268143] WRKY46, WRKY70, and WRKY53 positively regulate basal resistance to Pseudomonas syringae; and that they play overlapping and synergetic roles in plant basal defense. [PMID: 22325892] AtMYB44 modulates antagonistic interaction by activating SA-mediated defenses and repressing JA-mediated defenses through direct control of WRKY70 [PMID: 23067202] AtMYB44 regulates defense responses by transcriptional activation of downstream gene, WRKY70. [PMID: 23603962] WRKY70 and WRKY54 co-operate as negative regulators of stomatal closure and, consequently, osmotic stress tolerance in Arabidopsis, suggesting that they have an important role, not only in plant defense, but also in abiotic stress signaling. [PMID: 23815736] Data indicate that the nucleotides CGAC are essential for WRKY70-activated gene expression. [PMID: 24104863] A lower expression level of WRKY70 leads to significantly higher MYC2 expression through salicylic acid (SA)-jasmonic acid (JA) cross-talk. [PMID: 25339349] Bacillus cereus AR156 treatment significantly stimulated the transcription of WRKY70, but suppressed that of WRKY11 in Arabidopsis leaves. They were shown to be required for AR156 enhancing the activation of cellular defence responses. [PMID: 26433201] Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses [PMID: 28576847] data suggest that the elevated SA level in the wrky54wrky70 double mutant results in moderate accumulation of H2O2, in promoting cell wall fortification and consequently enhanced resistance to necrotrophs but is not sufficient to trigger hypersensitive reaction (HR)-like cell death and resistance to biotrophs/hemibiotrophs like Pst DC3000 [PMID: 28837631]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00408	DAP	27203113	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT3G56400.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Regulated by MYB44 (PubMed:23067202, PubMed:23603962). Basal expression levels require the presence of endogeneous salicylic acid (SA) (PubMed:14742872, PubMed:17310369). Induced by reactive oxygen species (ROS) (PubMed:22268143). Early but transient accumulation after osmotic stress (e.g. polyethylene glycol, PEG) (PubMed:23815736). Induced by SA; early induction is NPR1-independent, but full-scale induction is NPR1-dependent (PubMed:14742872, PubMed:22325892, PubMed:22268143, PubMed:26433201). Up-regulated by benzothiadiazole (BTH) (PubMed:26433201). Repressed by jasmonic acid (MeJA) by both COI1-dependent and COI1-independent pathways (PubMed:14742872, PubMed:18713432). Triggered by the pathogenic compatible bacteria E.carotovora subsp. carotovora SCC3193 (PubMed:14742872). Induced by P.syringae pv. tomato DC3000 (PubMed:17965588, PubMed:22325892). Stimulated by ATX1 (PubMed:17965588). Up-regulated by E.amylovora (PubMed:22316300). Accumulates during leaf and flower senescence (PubMed:17310369). Induced expression upon simultaneous feeding by caterpillars (e.g. P.xylostella) and aphids (e.g. B.brassicae) at a low density, but lower levels in plants induced with both caterpillars and a high aphid density (PubMed:25339349). Responsive to rhizobacterium B.cereus AR156 in leaves (PubMed:26433201). {ECO:0000269\|PubMed:14742872, ECO:0000269\|PubMed:17310369, ECO:0000269\|PubMed:17965588, ECO:0000269\|PubMed:18713432, ECO:0000269\|PubMed:22268143, ECO:0000269\|PubMed:22316300, ECO:0000269\|PubMed:22325892, ECO:0000269\|PubMed:23067202, ECO:0000269\|PubMed:23603962, ECO:0000269\|PubMed:23815736, ECO:0000269\|PubMed:25339349, ECO:0000269\|PubMed:26433201}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source	Upstream Regulator (A: Activate/R: Repress)
ATRM	AT2G24570 (R), AT4G31550 (R)

Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source	Target Gene (A: Activate/R: Repress)
ATRM	AT1G19670(R), AT1G75040(A), AT2G14560(A), AT2G14610(A), AT2G18660(A), AT3G57260(A), AT4G24240(R), AT5G44420(R)

Regulation -- Hormone ? help Back to Top
Source	Hormone
AHD	jasmonic acid, salicylic acid

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT5G24110
IntAct	Search Q9LY00

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT3G56400

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF421157	0.0	AF421157.1 Arabidopsis thaliana WRKY transcription factor 70 (WRKY70) mRNA, complete cds.
GenBank	AY039933	0.0	AY039933.1 Arabidopsis thaliana putative DNA-binding protein (At3g56400) mRNA, complete cds.
GenBank	AY142566	0.0	AY142566.1 Arabidopsis thaliana putative DNA-binding protein (At3g56400) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_191199.1	0.0	WRKY DNA-binding protein 70
Swissprot	Q9LY00	0.0	WRK70_ARATH; Probable WRKY transcription factor 70
TrEMBL	A0A178V9D0	0.0	A0A178V9D0_ARATH; WRKY70
STRING	AT3G56400.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4061	27	57
Representative plant	OGRP14	17	875

Link Out ? help Back to Top
Phytozome	AT3G56400.1
Entrez Gene	824807
iHOP	AT3G56400
wikigenes	AT3G56400

Publications ? help Back to Top
Eulgem T,Rushton PJ,Robatzek S,Somssich IE The WRKY superfamily of plant transcription factors. Trends Plant Sci., 2000. 5(5): p. 199-206 [PMID:10785665] Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Li J,Brader G,Palva ET The WRKY70 transcription factor: a node of convergence for jasmonate-mediated and salicylate-mediated signals in plant defense. Plant Cell, 2004. 16(2): p. 319-31 [PMID:14742872] Dong X NPR1, all things considered. Curr. Opin. Plant Biol., 2004. 7(5): p. 547-52 [PMID:15337097] Lorenzo O,Solano R Molecular players regulating the jasmonate signalling network. Curr. Opin. Plant Biol., 2005. 8(5): p. 532-40 [PMID:16039901] McGrath KC, et al. Repressor- and activator-type ethylene response factors functioning in jasmonate signaling and disease resistance identified via a genome-wide screen of Arabidopsis transcription factor gene expression. Plant Physiol., 2005. 139(2): p. 949-59 [PMID:16183832] Li J,Brader G,Kariola T,Palva ET WRKY70 modulates the selection of signaling pathways in plant defense. Plant J., 2006. 46(3): p. 477-91 [PMID:16623907] Brodersen P, et al. Arabidopsis MAP kinase 4 regulates salicylic acid- and jasmonic acid/ethylene-dependent responses via EDS1 and PAD4. Plant J., 2006. 47(4): p. 532-46 [PMID:16813576] AbuQamar S, et al. Expression profiling and mutant analysis reveals complex regulatory networks involved in Arabidopsis response to Botrytis infection. Plant J., 2006. 48(1): p. 28-44 [PMID:16925600] Kim KC,Fan B,Chen Z Pathogen-induced Arabidopsis WRKY7 is a transcriptional repressor and enhances plant susceptibility to Pseudomonas syringae. Plant Physiol., 2006. 142(3): p. 1180-92 [PMID:16963526] Wang D,Amornsiripanitch N,Dong X A genomic approach to identify regulatory nodes in the transcriptional network of systemic acquired resistance in plants. PLoS Pathog., 2006. 2(11): p. e123 [PMID:17096590] Journot-Catalino N,Somssich IE,Roby D,Kroj T The transcription factors WRKY11 and WRKY17 act as negative regulators of basal resistance in Arabidopsis thaliana. Plant Cell, 2006. 18(11): p. 3289-302 [PMID:17114354] Ciftci-Yilmaz S, et al. The EAR-motif of the Cys2/His2-type zinc finger protein Zat7 plays a key role in the defense response of Arabidopsis to salinity stress. J. Biol. Chem., 2007. 282(12): p. 9260-8 [PMID:17259181] Ulker B,Shahid Mukhtar M,Somssich IE The WRKY70 transcription factor of Arabidopsis influences both the plant senescence and defense signaling pathways. Planta, 2007. 226(1): p. 125-37 [PMID:17310369] Knoth C,Ringler J,Dangl JL,Eulgem T Arabidopsis WRKY70 is required for full RPP4-mediated disease resistance and basal defense against Hyaloperonospora parasitica. Mol. Plant Microbe Interact., 2007. 20(2): p. 120-8 [PMID:17313163] Miao Y,Zentgraf U The antagonist function of Arabidopsis WRKY53 and ESR/ESP in leaf senescence is modulated by the jasmonic and salicylic acid equilibrium. Plant Cell, 2007. 19(3): p. 819-30 [PMID:17369373] Libault M,Wan J,Czechowski T,Udvardi M,Stacey G Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor. Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11 [PMID:17722694] Alvarez-Venegas R,Abdallat AA,Guo M,Alfano JR,Avramova Z Epigenetic control of a transcription factor at the cross section of two antagonistic pathways. Epigenetics, 2007 Apr-Jun. 2(2): p. 106-13 [PMID:17965588] Meier S, et al. Co-expression and promoter content analyses assign a role in biotic and abiotic stress responses to plant natriuretic peptides. BMC Plant Biol., 2008. 8: p. 24 [PMID:18307823] Koornneef A,Pieterse CM Cross talk in defense signaling. Plant Physiol., 2008. 146(3): p. 839-44 [PMID:18316638] Knoth C,Eulgem T The oomycete response gene LURP1 is required for defense against Hyaloperonospora parasitica in Arabidopsis thaliana. Plant J., 2008. 55(1): p. 53-64 [PMID:18346188] Ascencio-Ib Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. Plant Physiol., 2008. 148(1): p. 436-54 [PMID:18650403] Kim CY,Bove J,Assmann SM Overexpression of wound-responsive RNA-binding proteins induces leaf senescence and hypersensitive-like cell death. New Phytol., 2008. 180(1): p. 57-70 [PMID:18705666] Ren CM, et al. Transcription factor WRKY70 displays important but no indispensable roles in jasmonate and salicylic acid signaling. J Integr Plant Biol, 2008. 50(5): p. 630-7 [PMID:18713432] Ishikawa K, et al. AtNUDX6, an ADP-ribose/NADH pyrophosphohydrolase in Arabidopsis, positively regulates NPR1-dependent salicylic acid signaling. Plant Physiol., 2010. 152(4): p. 2000-12 [PMID:20181750] Zhang Y, et al. Arabidopsis snc2-1D activates receptor-like protein-mediated immunity transduced through WRKY70. Plant Cell, 2010. 22(9): p. 3153-63 [PMID:20841424] Ndamukong I,Jones DR,Lapko H,Divecha N,Avramova Z Phosphatidylinositol 5-phosphate links dehydration stress to the activity of ARABIDOPSIS TRITHORAX-LIKE factor ATX1. PLoS ONE, 2010. 5(10): p. e13396 [PMID:20967218] Shang J, et al. A broad-spectrum, efficient and nontransgenic approach to control plant viruses by application of salicylic acid and jasmonic acid. Planta, 2011. 233(2): p. 299-308 [PMID:21046144] Zhou X,Jiang Y,Yu D WRKY22 transcription factor mediates dark-induced leaf senescence in Arabidopsis. Mol. Cells, 2011. 31(4): p. 303-13 [PMID:21359674] Sharon M,Freeman S,Sneh B Assessment of resistance pathways induced in Arabidopsis thaliana by hypovirulent Rhizoctonia spp. isolates. Phytopathology, 2011. 101(7): p. 828-38 [PMID:21385012] Atamian HS,Eulgem T,Kaloshian I SlWRKY70 is required for Mi-1-mediated resistance to aphids and nematodes in tomato. Planta, 2012. 235(2): p. 299-309 [PMID:21898085] von Saint Paul V, et al. The Arabidopsis glucosyltransferase UGT76B1 conjugates isoleucic acid and modulates plant defense and senescence. Plant Cell, 2011. 23(11): p. 4124-45 [PMID:22080599] Besseau S,Li J,Palva ET WRKY54 and WRKY70 co-operate as negative regulators of leaf senescence in Arabidopsis thaliana. J. Exp. Bot., 2012. 63(7): p. 2667-79 [PMID:22268143] Moreau M, et al. EDS1 contributes to nonhost resistance of Arabidopsis thaliana against Erwinia amylovora. Mol. Plant Microbe Interact., 2012. 25(3): p. 421-30 [PMID:22316300] Hu Y,Dong Q,Yu D Arabidopsis WRKY46 coordinates with WRKY70 and WRKY53 in basal resistance against pathogen Pseudomonas syringae. Plant Sci., 2012. 185-186: p. 288-97 [PMID:22325892] Mafra V, et al. Reference genes for accurate transcript normalization in citrus genotypes under different experimental conditions. PLoS ONE, 2012. 7(2): p. e31263 [PMID:22347455] Shim JS, et al. AtMYB44 regulates WRKY70 expression and modulates antagonistic interaction between salicylic acid and jasmonic acid signaling. Plant J., 2013. 73(3): p. 483-95 [PMID:23067202] Shim JS,Choi YD Direct regulation of WRKY70 by AtMYB44 in plant defense responses. Plant Signal Behav, 2013. 8(6): p. e20783 [PMID:23603962] Li J, et al. Defense-related transcription factors WRKY70 and WRKY54 modulate osmotic stress tolerance by regulating stomatal aperture in Arabidopsis. New Phytol., 2013. 200(2): p. 457-72 [PMID:23815736] Machens F,Becker M,Umrath F,Hehl R Identification of a novel type of WRKY transcription factor binding site in elicitor-responsive cis-sequences from Arabidopsis thaliana. Plant Mol. Biol., 2014. 84(4-5): p. 371-85 [PMID:24104863] Zhang X, et al. Arabidopsis cysteine-rich receptor-like kinase 45 positively regulates disease resistance to Pseudomonas syringae. Plant Physiol. Biochem., 2013. 73: p. 383-91 [PMID:24215930] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Brosché M, et al. Transcriptomics and functional genomics of ROS-induced cell death regulation by RADICAL-INDUCED CELL DEATH1. PLoS Genet., 2014. 10(2): p. e1004112 [PMID:24550736] Bao F, et al. Arabidopsis HSP90 protein modulates RPP4-mediated temperature-dependent cell death and defense responses. New Phytol., 2014. 202(4): p. 1320-34 [PMID:24611624] Kroes A,van Loon JJ,Dicke M Density-dependent interference of aphids with caterpillar-induced defenses in Arabidopsis: involvement of phytohormones and transcription factors. Plant Cell Physiol., 2015. 56(1): p. 98-106 [PMID:25339349] Jin J, et al. An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors. Mol. Biol. Evol., 2015. 32(7): p. 1767-73 [PMID:25750178] Wang F, et al. TaNAC1 acts as a negative regulator of stripe rust resistance in wheat, enhances susceptibility to Pseudomonas syringae, and promotes lateral root development in transgenic Arabidopsis thaliana. Front Plant Sci, 2015. 6: p. 108 [PMID:25774162] Jiang CH, et al. Transcription factors WRKY70 and WRKY11 served as regulators in rhizobacterium Bacillus cereus AR156-induced systemic resistance to Pseudomonas syringae pv. tomato DC3000 in Arabidopsis. J. Exp. Bot., 2016. 67(1): p. 157-74 [PMID:26433201] Kaurilind E,Xu E,Brosché M A genetic framework for H2O2 induced cell death in Arabidopsis thaliana. BMC Genomics, 2015. 16: p. 837 [PMID:26493993] Rodriguez-Salus M, et al. The Synthetic Elicitor 2-(5-Bromo-2-Hydroxy-Phenyl)-Thiazolidine-4-Carboxylic Acid Links Plant Immunity to Hormesis. Plant Physiol., 2016. 170(1): p. 444-58 [PMID:26530314] Onkokesung N,Reichelt M,van Doorn A,Schuurink RC,Dicke M Differential Costs of Two Distinct Resistance Mechanisms Induced by Different Herbivore Species in Arabidopsis. Plant Physiol., 2016. 170(2): p. 891-906 [PMID:26603653] Chen J, et al. Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses. 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