PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT3G47640.2

Common Name

BHLH47, EN139, F1P2.190, PYE

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 240aa MW: 26944.1 Da PI: 6.5155

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT3G47640.2	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	14.7	5.5e-05	28	75	1	52
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHH CS HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIk 52 +r ++ rEr R+++N+ f eL + l + ++ Ka+iL +A++++k AT3G47640.2 28 KRINKAVRERLKREHLNELFIELADTLELN----QQNSGKASILCEATRFLK 75 689999*********************997....566778889999999887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	1.13E-4	25	76	No hit	No description
SuperFamily	SSF47459	4.32E-11	26	91	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	11.522	27	77	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.4E-7	27	94	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010106	Biological Process	cellular response to iron ion starvation
GO:0055072	Biological Process	iron ion homeostasis
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000025	anatomy	root tip
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025281	anatomy	pollen
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 240 aa Download sequence Send to blast
MVSKTPSTSS DEANATADER CRKGKVPKRI NKAVRERLKR EHLNELFIEL ADTLELNQQN 60 SGKASILCEA TRFLKDVFGQ IESLRKEHAS LLSESSYVTT EKNELKEETS VLETEISKLQ 120 NEIEARANQS KPDLNTSPAP EYHHHHYQQQ HPERVSQFPG LPIFQGPGFQ QSATTLHPPA 180 TVLVLPIQPD PQTQDISEMT QAQQPLMFNS SNVSKPCPRY ASAADSWSSR LLGERLKASE

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.43911	0.0	root

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	252427_at	0.0
Expression Atlas	AT3G47640	-
AtGenExpress	AT3G47640	-
ATTED-II	AT3G47640	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269\|PubMed:12679534}.

Functional Description ? help Back to Top
Source	Description
TAIR	Encodes POPEYE (PYE), a bHLH transcription factor regulating response to iron deficiency in Arabidopsis roots.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT3G47640.2

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT4G14410, AT4G02590, AT5G08330, AT5G11260, AT5G51910, AT5G54680, AT1G03040, AT1G51070, AT1G69690
IntAct	Search Q9SN74

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT3G47640

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY080786	0.0	AY080786.1 Arabidopsis thaliana unknown protein (At3g47640) mRNA, complete cds.
GenBank	AY114018	0.0	AY114018.1 Arabidopsis thaliana unknown protein (At3g47640) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001190029.1	1e-178	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Refseq	NP_001190030.1	1e-178	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Refseq	NP_190348.1	1e-178	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Swissprot	Q9SN74	1e-180	BH047_ARATH; Transcription factor bHLH47
TrEMBL	A0A178VI35	1e-163	A0A178VI35_ARATH; PYE
STRING	AT3G47640.2	1e-178	(Arabidopsis thaliana)

Link Out ? help Back to Top
Phytozome	AT3G47640.2
Entrez Gene	823918
iHOP	AT3G47640
wikigenes	AT3G47640

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Heim MA, et al. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol., 2003. 20(5): p. 735-47 [PMID:12679534] Toledo-Ortiz G,Huq E,Quail PH The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell, 2003. 15(8): p. 1749-70 [PMID:12897250] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Bailey PC, et al. Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana. Plant Cell, 2003. 15(11): p. 2497-502 [PMID:14600211] Yang KY,Kim YM,Lee S,Song PS,Soh MS Overexpression of a mutant basic helix-loop-helix protein HFR1, HFR1-deltaN105, activates a branch pathway of light signaling in Arabidopsis. Plant Physiol., 2003. 133(4): p. 1630-42 [PMID:14645731] Guan Y,Nothnagel EA Binding of arabinogalactan proteins by Yariv phenylglycoside triggers wound-like responses in Arabidopsis cell cultures. Plant Physiol., 2004. 135(3): p. 1346-66 [PMID:15235117] Gong W, et al. The development of protein microarrays and their applications in DNA-protein and protein-protein interaction analyses of Arabidopsis transcription factors. Mol Plant, 2008. 1(1): p. 27-41 [PMID:19802365] Long TA, et al. The bHLH transcription factor POPEYE regulates response to iron deficiency in Arabidopsis roots. Plant Cell, 2010. 22(7): p. 2219-36 [PMID:20675571] Golisz A,Sugano M,Hiradate S,Fujii Y Microarray analysis of Arabidopsis plants in response to allelochemical L-DOPA. Planta, 2011. 233(2): p. 231-40 [PMID:20978802] Arabidopsis Interactome Mapping Consortium Evidence for network evolution in an Arabidopsis interactome map. Science, 2011. 333(6042): p. 601-7 [PMID:21798944] Ivanov R,Brumbarova T,Bauer P Fitting into the harsh reality: regulation of iron-deficiency responses in dicotyledonous plants. Mol Plant, 2012. 5(1): p. 27-42 [PMID:21873619] Efroni I, et al. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev. Cell, 2013. 24(4): p. 438-45 [PMID:23449474] Rodríguez-Celma J, et al. The transcriptional response of Arabidopsis leaves to Fe deficiency. Front Plant Sci, 2013. 4: p. 276 [PMID:23888164] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Martínez-Trujillo M, et al. Chromate alters root system architecture and activates expression of genes involved in iron homeostasis and signaling in Arabidopsis thaliana. Plant Mol. Biol., 2014. 86(1-2): p. 35-50 [PMID:24928490] Li H,Wang L,Yang ZM Co-expression analysis reveals a group of genes potentially involved in regulation of plant response to iron-deficiency. Gene, 2015. 554(1): p. 16-24 [PMID:25300251] Selote D,Samira R,Matthiadis A,Gillikin JW,Long TA Iron-binding E3 ligase mediates iron response in plants by targeting basic helix-loop-helix transcription factors. Plant Physiol., 2015. 167(1): p. 273-86 [PMID:25452667] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786]