PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT3G44460.1

Common Name

AtbZIP67, BZIP67, DPBF2, F14L2.10

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bZIP

Protein Properties

Length: 331aa MW: 37665.1 Da PI: 6.6925

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT3G44460.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	41.6	2.6e-13	249	300	5	56
CHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 5 krerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkev 56 +r+rr++kNRe+A rsR+R++a++ eLe + +L++eN++Lk+ +ee +k+ AT3G44460.1 249 RRQRRMIKNRESAARSRARRQAYTVELELELNNLTEENTKLKEIVEENEKKR 300 79****************************************9999988765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00338	1.8E-8	242	310	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	10.772	247	299	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	3.19E-9	249	298	No hit	No description
Gene3D	G3DSA:1.20.5.170	3.5E-12	249	300	No hit	No description
Pfam	PF00170	1.1E-11	249	301	IPR004827	Basic-leucine zipper domain
PROSITE pattern	PS00036	0	252	267	IPR004827	Basic-leucine zipper domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009738	Biological Process	abscisic acid-activated signaling pathway
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0033613	Molecular Function	activating transcription factor binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0020030	anatomy	cotyledon

Sequence ? help Back to Top
Protein Sequence Length: 331 aa Download sequence Send to blast
MSVFESETSN FHVYNNHEIQ TQPQMQTFLS EEEPVGRQNS ILSLTLDEIQ MKSGKSFGAM 60 NMDEFLANLW TTVEENDNEG GGAHNDGEKP AVLPRQGSLS LPVPLCKKTV DEVWLEIQNG 120 VQQHPPSSNS GQNSAENIRR QQTLGEITLE DFLVKAGVVQ EPLKTTMRMS SSDFGYNPEF 180 GVGLHCQNQN NYGDNRSVYS ENRPFYSVLG ESSSCMTGNG RSNQYLTGLD AFRIKKRIID 240 GPPEILMERR QRRMIKNRES AARSRARRQA YTVELELELN NLTEENTKLK EIVEENEKKR 300 RQEIISRSKQ VTKEKSGDKL RKIRRMASAG W

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.5333	0.0	seed

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	186510667	0.0
Genevisible	252645_at	0.0
Expression Atlas	AT3G44460	-
AtGenExpress	AT3G44460	-
ATTED-II	AT3G44460	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed in embryo during the latest stages of seed maturation. {ECO:0000269\|PubMed:15642716}.
Uniprot	TISSUE SPECIFICITY: Predominantly expressed in seeds. {ECO:0000269\|PubMed:12376636}.

Functional Description ? help Back to Top
Source	Description
TAIR	basic leucine zipper transcription factor (BZIP67), identical to basic leucine zipper transcription factor GI:18656053 from (Arabidopsis thaliana); identical to cDNA basic leucine zipper transcription factor (atbzip67 gene) GI:18656052. Located in the nucleus and expressed during seed maturation in the cotyledons.
UniProt	Could participate in abscisic acid-regulated gene expression during seed development. {ECO:0000250}.

Function -- GeneRIF ? help Back to Top
A transcriptional complex containing L1L, NF-YC2, and bZIP67 is induced by LEC1 during embryogenesis and specifies high levels of ALA production for storage oil by activating FAD3 expression. [bZIP67] [PMID: 23995083]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT3G44460.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT3G56850, AT4G34000, AT1G14920, AT1G49720
IntAct	Search Q8RYD6

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT3G44460

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ419600	0.0	AJ419600.1 Arabidopsis thaliana mRNA for basic leucine zipper transcription factor (atbzip67 gene).
GenBank	BT002923	0.0	BT002923.1 Arabidopsis thaliana clone RAFL15-01-K19 (R20103) putative bZIP protein (At3g44460) mRNA, complete cds.
GenBank	BT004342	0.0	BT004342.1 Arabidopsis thaliana clone U20103 putative bZIP protein (At3g44460) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_566870.1	0.0	Basic-leucine zipper (bZIP) transcription factor family protein
Swissprot	Q8RYD6	0.0	AI5L1_ARATH; ABSCISIC ACID-INSENSITIVE 5-like protein 1
TrEMBL	A0A178VDV0	0.0	A0A178VDV0_ARATH; DPBF2
STRING	AT3G44460.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM11652	22	30
Representative plant	OGRP13774	2	3

Link Out ? help Back to Top
Phytozome	AT3G44460.1
Entrez Gene	823571
iHOP	AT3G44460
wikigenes	AT3G44460

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Jakoby M, et al. bZIP transcription factors in Arabidopsis. Trends Plant Sci., 2002. 7(3): p. 106-11 [PMID:11906833] Bensmihen S, et al. The homologous ABI5 and EEL transcription factors function antagonistically to fine-tune gene expression during late embryogenesis. Plant Cell, 2002. 14(6): p. 1391-403 [PMID:12084834] Brocard IM,Lynch TJ,Finkelstein RR Regulation and role of the Arabidopsis abscisic acid-insensitive 5 gene in abscisic acid, sugar, and stress response. Plant Physiol., 2002. 129(4): p. 1533-43 [PMID:12177466] Kim SY,Ma J,Perret P,Li Z,Thomas TL Arabidopsis ABI5 subfamily members have distinct DNA-binding and transcriptional activities. Plant Physiol., 2002. 130(2): p. 688-97 [PMID:12376636] Suzuki M,Ketterling MG,Li QB,McCarty DR Viviparous1 alters global gene expression patterns through regulation of abscisic acid signaling. Plant Physiol., 2003. 132(3): p. 1664-77 [PMID:12857845] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Deppmann CD, et al. Dimerization specificity of all 67 B-ZIP motifs in Arabidopsis thaliana: a comparison to Homo sapiens B-ZIP motifs. Nucleic Acids Res., 2004. 32(11): p. 3435-45 [PMID:15226410] Bensmihen S,Giraudat J,Parcy F Characterization of three homologous basic leucine zipper transcription factors (bZIP) of the ABI5 family during Arabidopsis thaliana embryo maturation. J. Exp. Bot., 2005. 56(412): p. 597-603 [PMID:15642716] Kagaya Y, et al. Indirect ABA-dependent regulation of seed storage protein genes by FUSCA3 transcription factor in Arabidopsis. Plant Cell Physiol., 2005. 46(2): p. 300-11 [PMID:15695463] de Folter S, et al. Comprehensive interaction map of the Arabidopsis MADS Box transcription factors. Plant Cell, 2005. 17(5): p. 1424-33 [PMID:15805477] Fujita Y, et al. AREB1 Is a transcription activator of novel ABRE-dependent ABA signaling that enhances drought stress tolerance in Arabidopsis. Plant Cell, 2005. 17(12): p. 3470-88 [PMID:16284313] Deppmann CD,Alvania RS,Taparowsky EJ Cross-species annotation of basic leucine zipper factor interactions: Insight into the evolution of closed interaction networks. Mol. Biol. Evol., 2006. 23(8): p. 1480-92 [PMID:16731568] Garcia ME,Lynch T,Peeters J,Snowden C,Finkelstein R A small plant-specific protein family of ABI five binding proteins (AFPs) regulates stress response in germinating Arabidopsis seeds and seedlings. Plant Mol. Biol., 2008. 67(6): p. 643-58 [PMID:18484180] Yamamoto A, et al. Arabidopsis NF-YB subunits LEC1 and LEC1-LIKE activate transcription by interacting with seed-specific ABRE-binding factors. Plant J., 2009. 58(5): p. 843-56 [PMID:19207209] Arabidopsis Interactome Mapping Consortium Evidence for network evolution in an Arabidopsis interactome map. Science, 2011. 333(6042): p. 601-7 [PMID:21798944] Causier B,Ashworth M,Guo W,Davies B The TOPLESS interactome: a framework for gene repression in Arabidopsis. Plant Physiol., 2012. 158(1): p. 423-38 [PMID:22065421] Lynch T,Erickson BJ,Finkelstein RR Direct interactions of ABA-insensitive(ABI)-clade protein phosphatase(PP)2Cs with calcium-dependent protein kinases and ABA response element-binding bZIPs may contribute to turning off ABA response. Plant Mol. Biol., 2012. 80(6): p. 647-58 [PMID:23007729] Mendes A, et al. bZIP67 regulates the omega-3 fatty acid content of Arabidopsis seed oil by activating fatty acid desaturase3. Plant Cell, 2013. 25(8): p. 3104-16 [PMID:23995083] Lim S, et al. ABA-insensitive3, ABA-insensitive5, and DELLAs Interact to activate the expression of SOMNUS and other high-temperature-inducible genes in imbibed seeds in Arabidopsis. Plant Cell, 2013. 25(12): p. 4863-78 [PMID:24326588]