PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT3G20310.1

Common Name

ATERF7, ATERF-7, ERF083, ERF7, ERF-7, MQC12.5

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 244aa MW: 26508.8 Da PI: 9.0468

Description

ethylene response factor 7

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT3G20310.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	57.7	2.8e-18	25	75	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ++y+GVr ++ +gr++AeIrdp + + r++lg+f++a +Aa+a++ a+++l+g AT3G20310.1 25 PRYRGVRKRP-WGRFAAEIRDPLK---KSRVWLGTFDSAVDAARAYDTAARNLRG 75 68******.******743...5***********************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	2.5E-11	25	75	IPR001471	AP2/ERF domain
CDD	cd00018	1.50E-30	25	85	No hit	No description
PROSITE profile	PS51032	22.985	26	83	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.42E-21	26	85	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	1.6E-31	26	83	IPR001471	AP2/ERF domain
SMART	SM00380	1.2E-37	26	89	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.1E-9	27	38	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.1E-9	49	65	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006952	Biological Process	defense response
GO:0009414	Biological Process	response to water deprivation
GO:0009737	Biological Process	response to abscisic acid
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0005515	Molecular Function	protein binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009001	anatomy	fruit
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0009062	anatomy	gynoecium
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025195	anatomy	pollen tube cell
PO:0025281	anatomy	pollen
PO:0001016	developmental stage	L mature pollen stage
PO:0001017	developmental stage	M germinated pollen stage
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 244 aa Download sequence Send to blast
MRKGRGSSVV GPALPVTAGG SVKEPRYRGV RKRPWGRFAA EIRDPLKKSR VWLGTFDSAV 60 DAARAYDTAA RNLRGPKAKT NFPIDCSPSS PLQPLTYLHN QNLCSPPVIQ NQIDPFMDHR 120 LYGGGNFQEQ QQQQIISRPA SSSMSSTVKS CSGPRPMEAA AASSSVAKPL HAIKRYPRTP 180 PVAPEDCHSD CDSSSSVIDD GDDIASSSSR RKTPFQFDLN FPPLDGVDLF AGGIDDLHCT 240 DLRL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	2e-20	27	84	3	61	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A	2e-20	23	84	2	64	ATERF1
3gcc_A	2e-20	23	84	2	64	ATERF1
5wx9_A	6e-20	19	92	7	81	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.20161	0.0	floral meristem\| flower\| vegetative tissue

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	14335149	0.0
Genevisible	257675_at	0.0
Expression Atlas	AT3G20310	-
AtGenExpress	AT3G20310	-
ATTED-II	AT3G20310	-

Functional Description ? help Back to Top
Source	Description
TAIR	Encodes a member of the ERF (ethylene response factor) subfamily B-1 of ERF/AP2 transcription factor family (ATERF-7). The protein contains one AP2 domain. Phosphorylated by PKS3 in vitro. Involved in ABA-mediated responses. Acts as a repressor of GCC boxmediated transcription together with AtSin3 and HDA19.
UniProt	Involved in the regulation of gene expression by abscisic acid, stress factors and by components of stress signal transduction pathways. Transcription factor that binds to the GCC-box pathogenesis-related promoter element. Part of a transcriptional repressor complex including a histone deacetylase. {ECO:0000269\|PubMed:11487705, ECO:0000269\|PubMed:15994908}.

Function -- GeneRIF ? help Back to Top
Studies indicate that ethylene response factor 7 (ERF-VIIs) are directly regulated by oxygen, in that their protein half-life is determined by an oxygen-dependent mechanism of proteasomal degradation [Review]. [PMID: 29269576]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00366	DAP	27203113	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT3G20310.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source	Target Gene (A: Activate/R: Repress)
ATRM	AT5G44420(R)

Regulation -- Hormone ? help Back to Top
Source	Hormone
AHD	abscisic acid, ethylene

Interaction ? help Back to Top
Source	Intact With
IntAct	Search Q9LDE4

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT3G20310

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB024036	0.0	AB024036.1 Arabidopsis thaliana genomic DNA, chromosome 3, P1 clone: MQC12.
GenBank	AB032201	0.0	AB032201.1 Arabidopsis thaliana mRNA for ERF transcription factor 7, complete cds.
GenBank	AK228460	0.0	AK228460.1 Arabidopsis thaliana mRNA for putative ethylene responsive element binding factor, complete cds, clone: RAFL15-05-J12.
GenBank	AY037254	0.0	AY037254.1 Arabidopsis thaliana AT3g20310/MQC12_6 mRNA, complete cds.
GenBank	AY094001	0.0	AY094001.1 Arabidopsis thaliana AT3g20310/MQC12_6 mRNA, complete cds.
GenBank	CP002686	0.0	CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_188666.1	1e-180	ethylene response factor 7
Swissprot	Q9LDE4	0.0	ERF83_ARATH; Ethylene-responsive transcription factor 7
TrEMBL	A0A178VH38	1e-179	A0A178VH38_ARATH; ERF7
STRING	AT3G20310.1	1e-179	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT3G20310.1
Entrez Gene	821575
iHOP	AT3G20310
wikigenes	AT3G20310

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Ohta M,Matsui K,Hiratsu K,Shinshi H,Ohme-Takagi M Repression domains of class II ERF transcriptional repressors share an essential motif for active repression. Plant Cell, 2001. 13(8): p. 1959-68 [PMID:11487705] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Cluis CP,Mouchel CF,Hardtke CS The Arabidopsis transcription factor HY5 integrates light and hormone signaling pathways. Plant J., 2004. 38(2): p. 332-47 [PMID:15078335] Song CP, et al. Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses. Plant Cell, 2005. 17(8): p. 2384-96 [PMID:15994908] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Babula D, et al. Genes involved in biosynthesis and signalisation of ethylene in Brassica oleracea and Arabidopsis thaliana: identification and genome comparative mapping of specific gene homologues. Theor. Appl. Genet., 2006. 112(3): p. 410-20 [PMID:16311726] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Nemhauser JL,Hong F,Chory J Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses. Cell, 2006. 126(3): p. 467-75 [PMID:16901781] Jung J, et al. The barley ERF-type transcription factor HvRAF confers enhanced pathogen resistance and salt tolerance in Arabidopsis. Planta, 2007. 225(3): p. 575-88 [PMID:16937017] Manavella PA, et al. Cross-talk between ethylene and drought signalling pathways is mediated by the sunflower Hahb-4 transcription factor. Plant J., 2006. 48(1): p. 125-37 [PMID:16972869] Galuschka C,Schindler M,Bülow L,Hehl R AthaMap web tools for the analysis and identification of co-regulated genes. Nucleic Acids Res., 2007. 35(Database issue): p. D857-62 [PMID:17148485] Wang Y, et al. Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. Plant Physiol., 2008. 148(3): p. 1201-11 [PMID:18775970] Kagale S,Links MG,Rozwadowski K Genome-wide analysis of ethylene-responsive element binding factor-associated amphiphilic repression motif-containing transcriptional regulators in Arabidopsis. Plant Physiol., 2010. 152(3): p. 1109-34 [PMID:20097792] Arabidopsis Interactome Mapping Consortium Evidence for network evolution in an Arabidopsis interactome map. Science, 2011. 333(6042): p. 601-7 [PMID:21798944] Klopffleisch K, et al. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Mol. Syst. Biol., 2011. 7: p. 532 [PMID:21952135] Gaudinier A, et al. Enhanced Y1H assays for Arabidopsis. Nat. Methods, 2011. 8(12): p. 1053-5 [PMID:22037706] Causier B,Ashworth M,Guo W,Davies B The TOPLESS interactome: a framework for gene repression in Arabidopsis. Plant Physiol., 2012. 158(1): p. 423-38 [PMID:22065421] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Jin J, et al. An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors. Mol. Biol. Evol., 2015. 32(7): p. 1767-73 [PMID:25750178] Giuntoli B,Perata P Group VII Ethylene Response Factors in Arabidopsis: Regulation and Physiological Roles. Plant Physiol., 2018. 176(2): p. 1143-1155 [PMID:29269576] Riechmann JL,Meyerowitz EM The AP2/EREBP family of plant transcription factors. Biol. Chem., 1998. 379(6): p. 633-46 [PMID:9687012]