PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G09370.2
Common NameAtMYB3R3, MYB3R-3
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family MYB
Protein Properties Length: 510aa    MW: 56737.8 Da    PI: 7.5698
Description myb domain protein 3r-3
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G09370.2genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding52.79.6e-1783129148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g WT+eEde l +av  + g++Wk Ia+ ++  Rt+ qc +rwqk+l
      AT3G09370.2  83 KGGWTPEEDETLRQAVDTFKGKSWKNIAKSFP-DRTEVQCLHRWQKVL 129
                      688*****************************.************986 PP
2Myb_DNA-binding60.34.2e-19135181148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g+WT eEde++v++v+++G+  W+ Ia+ ++ gR +kqc++rw+++l
      AT3G09370.2 135 KGPWTHEEDEKIVELVEKYGPAKWSIIAQSLP-GRIGKQCRERWHNHL 181
                      79******************************.*************97 PP
3Myb_DNA-binding55.11.7e-17187230146
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      +++WTteE+  l +a++ +G++ W+ Ia+ ++ gRt++ +k++w++
      AT3G09370.2 187 KDAWTTEEEVALMNAHRSHGNK-WAEIAKVLP-GRTDNAIKNHWNS 230
                      679*******************.*********.***********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129416.20278129IPR017930Myb domain
SMARTSM007172.5E-1482131IPR001005SANT/Myb domain
PfamPF002492.0E-1583129IPR001005SANT/Myb domain
SuperFamilySSF466891.08E-1584139IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.604.3E-2085139IPR009057Homeodomain-like
CDDcd001675.84E-1386129No hitNo description
PROSITE profilePS5129432.202130185IPR017930Myb domain
SuperFamilySSF466894.03E-32132228IPR009057Homeodomain-like
SMARTSM007172.0E-17134183IPR001005SANT/Myb domain
CDDcd001672.14E-15137181No hitNo description
PfamPF139212.6E-18138195No hitNo description
Gene3DG3DSA:1.10.10.602.2E-27140188IPR009057Homeodomain-like
PROSITE profilePS5129421.811186236IPR017930Myb domain
SMARTSM007179.4E-16186234IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.606.2E-23189235IPR009057Homeodomain-like
CDDcd001673.51E-12189232No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006357Biological Processregulation of transcription from RNA polymerase II promoter
GO:0030154Biological Processcell differentiation
GO:0005634Cellular Componentnucleus
GO:0000981Molecular FunctionRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001135Molecular Functiontranscription factor activity, RNA polymerase II transcription factor recruiting
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 510 aa     Download sequence    Send to blast
MSSTFNPAAS SPDEMMDLQE ETGEVKIEDQ CVENKQSTPA SCSSVSEGSA GSSHKSPTIA  60
SPATVSPTHR YLGRTSGPIR RAKGGWTPEE DETLRQAVDT FKGKSWKNIA KSFPDRTEVQ  120
CLHRWQKVLN PDLIKGPWTH EEDEKIVELV EKYGPAKWSI IAQSLPGRIG KQCRERWHNH  180
LNPDINKDAW TTEEEVALMN AHRSHGNKWA EIAKVLPGRT DNAIKNHWNS SLKKKSEFYL  240
LTGRLPPPTT TRNGVPDSVT KRSSSAQKRV FGSVAQTSSV TTDVNNLAED GNGQINSSVP  300
VEEVVAASRM TSLNEYARSP QLPNPEPLPE NGGAANNGYH LYYTPQIDYY RASEVDTQRM  360
YGNECGCSPS ASPVSFFTPP PCRNVHSNGS TPRSPESYLR EAGRTYPNTP SIFRKRRPRV  420
VVQDNNNAKK TDEAKEVDQK VNDGKDSSEI QNNGSNAYNL SPPYRIRSKR TAVFKSRQLE  480
FISREEEKAD DETKSSEKDM LIDGDSQLLG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h88_C1e-69822355158MYB PROTO-ONCOGENE PROTEIN
1h89_C1e-69822355158MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.118890.0flower
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO143345810.0
Genevisible259007_at0.0
Expression AtlasAT3G09370-
AtGenExpressAT3G09370-
ATTED-IIAT3G09370-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed both in proliferating and maturing stages of leaves. {ECO:0000269|PubMed:26069325}.
Functional Description ? help Back to Top
Source Description
TAIRputative c-myb-like transcription factor (MYB3R3) mRNA,
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250|UniProtKB:Q94FL9, ECO:0000269|PubMed:26069325}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G09370.2
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Slightly induced by ethylene, auxin (IAA), jasmonic acid (JA) and salicylic acid (SA). {ECO:0000269|PubMed:16463103}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G09370
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY1426490.0AY142649.1 Arabidopsis thaliana putative MYB family transcription factor (At3g09370) mRNA, complete cds.
GenBankAY5196510.0AY519651.1 Arabidopsis thaliana MYB transcription factor (At3g09370) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001078127.10.0myb domain protein 3r-3
SwissprotQ8H1P90.0MB3R3_ARATH; Transcription factor MYB3R-3
TrEMBLA0A178VAG00.0A0A178VAG0_ARATH; MYB3R-3
STRINGAT3G09370.20.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM16672887
Representative plantOGRP5171784
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Stracke R,Werber M,Weisshaar B
    The R2R3-MYB gene family in Arabidopsis thaliana.
    Curr. Opin. Plant Biol., 2001. 4(5): p. 447-56
    [PMID:11597504]
  3. Yanhui C, et al.
    The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.
    Plant Mol. Biol., 2006. 60(1): p. 107-24
    [PMID:16463103]
  4. Haga N, et al.
    R1R2R3-Myb proteins positively regulate cytokinesis through activation of KNOLLE transcription in Arabidopsis thaliana.
    Development, 2007. 134(6): p. 1101-10
    [PMID:17287251]
  5. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  6. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  7. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  8. Chen P, et al.
    Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage.
    Nat Commun, 2017. 8(1): p. 635
    [PMID:28935922]