PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G02990.1
Common NameATHSFA1E, F13E7.6, HSF06, HSF2, HSFA1E
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family HSF
Protein Properties Length: 468aa    MW: 51962.9 Da    PI: 4.5576
Description heat shock transcription factor A1E
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G02990.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind113.41.5e-35241152102
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl+k+y++++d+ +++++sws+ +nsfvv++  efak+ LpkyFkh+nf+SFvRQLn+YgF+kv+ ++         weF+++ F +g+k+ l++i 
   AT3G02990.1  24 FLSKTYDMVDDPLTDDVVSWSSGNNSFVVWNVPEFAKQFLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQKQILKSIV 111
                   9****************************************************************999.........******************** PP

                   XXXX CS
  HSF_DNA-bind  99 rkks 102
                   r+k 
   AT3G02990.1 112 RRKP 115
                   *986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.7E-3815108IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467859.93E-3420113IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004156.0E-5720113IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000563.0E-192447IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004471.7E-3024113IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000563.0E-196274IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043406387IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000563.0E-197587IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 468 aa     Download sequence    Send to blast
MGTVCESVAT AKSSTAVMSS IPPFLSKTYD MVDDPLTDDV VSWSSGNNSF VVWNVPEFAK  60
QFLPKYFKHN NFSSFVRQLN TYGFRKVDPD RWEFANEGFL RGQKQILKSI VRRKPAQVQP  120
PQQPQVQHSS VGACVEVGKF GLEEEVERLQ RDKNVLMQEL VRLRQQQQVT EHHLQNVGQK  180
VHVMEQRQQQ MMSFLAKAVQ SPGFLNQFSQ QSNEANQHIS ESNKKRRLPV EDQMNSGSHG  240
VNGLSRQIVR YQSSMNDATN TMLQQIQQMS NAPSHESLSS NNGSFLLGDV PNSNISDNGS  300
SSNGSPEVTL ADVSSIPAGF YPAMKYHEPC ETNQVMETNL PFSQGDLLPP TQGAAASGSS  360
SSDLVGCETD NGECLDPIMA VLDGALELEA DTLNELLPEV QDSFWEQFIG ESPVIGETDE  420
LISGSVENEL ILEQLELQST LSNVWSKNQQ MNHLTEQMGL LTSDALRK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A2e-261911315120Heat shock factor protein 1
5d5u_B2e-261911324129Heat shock factor protein 1
5d5v_B2e-261911324129Heat shock factor protein 1
5d5v_D2e-261911324129Heat shock factor protein 1
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1865097050.0
Genevisible258603_at0.0
Expression AtlasAT3G02990-
AtGenExpressAT3G02990-
ATTED-IIAT3G02990-
Functional Description ? help Back to Top
Source Description
TAIRmember of Heat Stress Transcription Factor (Hsf) family
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
Function -- GeneRIF ? help Back to Top
  1. These findings indicated that HsfA1d and HsfA1e not only regulate HsfA2 expression but also function as key regulators of the Hsf signaling network in response to environmental stress.
    [PMID: 21471117]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00328DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G02990.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT2G26150(A)
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G02990
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0263650.0BT026365.1 Arabidopsis thaliana At3g02990 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_186949.10.0heat shock transcription factor A1E
SwissprotQ9SCW50.0HFA1E_ARATH; Heat stress transcription factor A-1e
TrEMBLA0A178VCY30.0A0A178VCY3_ARATH; HSFA1E
STRINGAT3G02990.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM22362371
Representative plantOGRP9617233
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Nover L, et al.
    Arabidopsis and the heat stress transcription factor world: how many heat stress transcription factors do we need?
    Cell Stress Chaperones, 2001. 6(3): p. 177-89
    [PMID:11599559]
  3. Zhu H, et al.
    Syntenic relationships between Medicago truncatula and Arabidopsis reveal extensive divergence of genome organization.
    Plant Physiol., 2003. 131(3): p. 1018-26
    [PMID:12644654]
  4. Lee J, et al.
    Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development.
    Plant Cell, 2007. 19(3): p. 731-49
    [PMID:17337630]
  5. Guo J, et al.
    Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis.
    J Genet Genomics, 2008. 35(2): p. 105-18
    [PMID:18407058]
  6. Nishizawa-Yokoi A, et al.
    HsfA1d and HsfA1e involved in the transcriptional regulation of HsfA2 function as key regulators for the Hsf signaling network in response to environmental stress.
    Plant Cell Physiol., 2011. 52(5): p. 933-45
    [PMID:21471117]
  7. Yoshida T, et al.
    Arabidopsis HsfA1 transcription factors function as the main positive regulators in heat shock-responsive gene expression.
    Mol. Genet. Genomics, 2011. 286(5-6): p. 321-32
    [PMID:21931939]
  8. Liu HC,Charng YY
    Acquired thermotolerance independent of heat shock factor A1 (HsfA1), the master regulator of the heat stress response.
    Plant Signal Behav, 2012. 7(5): p. 547-50
    [PMID:22516818]
  9. Liu J, et al.
    An autoregulatory loop controlling Arabidopsis HsfA2 expression: role of heat shock-induced alternative splicing.
    Plant Physiol., 2013. 162(1): p. 512-21
    [PMID:23503691]
  10. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  11. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]