PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G46810.1
Common NameBHLH70, EN13, F19D11.9
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 371aa    MW: 43000.5 Da    PI: 7.3647
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G46810.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.16.6e-13191241154
                  CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
          HLH   1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                  +r++h ++Er+RR+++N  ++ Lr+++P++   + ++ + a+i+  A++++k L
  AT2G46810.1 191 QRMTHIAVERNRRRQMNVHLNSLRSIIPSS---YIQRGDQASIVGGAIDFVKIL 241
                  79****************************...9***************99866 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000833.75E-10189246No hitNo description
PROSITE profilePS5088814.557190241IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474596.54E-16190257IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000104.6E-10191241IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.105.5E-13191255IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003536.3E-10196247IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
Sequence ? help Back to Top
Protein Sequence    Length: 371 aa     Download sequence    Send to blast
MFVLRVSNQS FKLHQQVQCK DEIFCLDQKV NVRRSLQVQE TVEDHQSFAL EEEEQQLSTP  60
SLLQDTTIPF LQMLQQSEDP SPFLSFKDPS FLALLSLQTL EKPWELENYL PHEVPEFHSP  120
IHSETNHYYH NPSLEGVNEA ISNQELPFNP LENARSRRKR KNNNLASLMT REKRKRRRTK  180
PTKNIEEIES QRMTHIAVER NRRRQMNVHL NSLRSIIPSS YIQRGDQASI VGGAIDFVKI  240
LEQQLQSLEA QKRSQQSDDN KEQIPEDNSL RNISSNKLRA SNKEEQSSKL KIEATVIESH  300
VNLKIQCTRK QGQLLRSIIL LEKLRFTVLH LNITSPTNTS VSYSFNLKME DECNLGSADE  360
ITAAIRQIFD S
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1158177KRKNNNLASLMTREKRKRRR
2172177KRKRRR
3173177RKRRR
4173178RKRRRT
5173180RKRRRTKP
6191202RMTHIAVERNRR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.364510.0flower
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO425699860.0
Expression AtlasAT2G46810-
AtGenExpressAT2G46810-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G46810.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G46810
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB6784340.0AB678434.1 Arabidopsis thaliana mRNA for basic helix-loop-helix DNA-binding superfamily protein, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_182204.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotO810370.0BH070_ARATH; Transcription factor bHLH70
TrEMBLA0A384KPF20.0A0A384KPF2_ARATH; Uncharacterized protein
TrEMBLI2FGF60.0I2FGF6_ARATH; Basic helix-loop-helix (BHLH) DNA-binding superfamily protein
STRINGAT2G46810.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM31192666
Representative plantOGRP25315131
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. Scheible WR, et al.
    Genome-wide reprogramming of primary and secondary metabolism, protein synthesis, cellular growth processes, and the regulatory infrastructure of Arabidopsis in response to nitrogen.
    Plant Physiol., 2004. 136(1): p. 2483-99
    [PMID:15375205]
  6. Rehrauer H, et al.
    AGRONOMICS1: a new resource for Arabidopsis transcriptome profiling.
    Plant Physiol., 2010. 152(2): p. 487-99
    [PMID:20032078]
  7. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  8. Hanada K, et al.
    Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
    Mol. Biol. Evol., 2011. 28(1): p. 377-82
    [PMID:20736450]