PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT2G33835.1

Common Name

FES1, T1B8

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

C3H

Protein Properties

Length: 587aa MW: 64375.5 Da PI: 6.4605

Description

C3H family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G33835.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-CCCH	20.6	7.9e-07	101	121	5	26
--SGGGGTS--TTTTT-SS-SS CS zf-CCCH 5 lCrffartGtCkyGdrCkFaHg 26 +C+ffa+ G+C G +CkF H+ AT2G33835.1 101 PCKFFAK-GWCFNGVSCKFLHV 121 7****.***********7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF90229	6.02E-6	96	120	IPR000571	Zinc finger, CCCH-type
PROSITE profile	PS50103	14.314	96	123	IPR000571	Zinc finger, CCCH-type
Gene3D	G3DSA:4.10.1000.10	9.3E-4	101	122	IPR000571	Zinc finger, CCCH-type
Pfam	PF00642	1.2E-4	101	121	IPR000571	Zinc finger, CCCH-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009908	Biological Process	flower development
GO:0010220	Biological Process	positive regulation of vernalization response
GO:0030154	Biological Process	cell differentiation
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0046872	Molecular Function	metal ion binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000025	anatomy	root tip
PO:0000037	anatomy	shoot apex
PO:0000293	anatomy	guard cell
PO:0009015	anatomy	portion of vascular tissue

Sequence ? help Back to Top
Protein Sequence Length: 587 aa Download sequence Send to blast
MSDSDMDIDD DEVEQKVQVH TIVRESELFD KPPIQASNSH NDVKRHSVTT PLDEQSKIIK 60 EQAFAQDNGT LPRFPAPGIP PRSFFTGGGG NEPEQKRAAL PCKFFAKGWC FNGVSCKFLH 120 VKENSNCTSQ QLAENSMAGN GGIRSDLERR ILDSREGVRV SQLSENGVTS LPTREDISFM 180 NPQRVFSSMS FVNPPGSQRV FPFNNEMRFM PSFENIRRES LKQTYGADFT DNRSLVINNA 240 NSFALRSSFV HEHRPSISSY LKTDMGSAGP AWTGSLSSSV PMNDRASTVG DFENGNSLSG 300 SGSLPTLQGV AVSSDKGAEA NTTSTKKKVS SDDWEPSEPF KASFTIPPYI LPSSDALYDP 360 FTDIENLGDR PLNDSLSSKG EHARKSSCQQ KDGDSASGPQ ARDCKNDDKS SSCSQNQHQE 420 TVARSLEAHG VVEGVATSVV DQNDTATPSK EISSATAAEN RVVLKRIKPA GHDSWHRSDG 480 SSYKKTKKSD EIDGEVRSDA GMKVMRLFRT AVVETIKEML KPLWREGRLT KDVHNMIVKK 540 AAEKVVGAAV QFHQVPTDTE SVDQYLGLSG TRIVKLVEGY VEKYGKP

Sequence ? help Back to Top

Protein Sequence Length: 587 aa Download sequence Send to blast

MSDSDMDIDD DEVEQKVQVH TIVRESELFD KPPIQASNSH NDVKRHSVTT PLDEQSKIIK  60
EQAFAQDNGT LPRFPAPGIP PRSFFTGGGG NEPEQKRAAL PCKFFAKGWC FNGVSCKFLH  120
VKENSNCTSQ QLAENSMAGN GGIRSDLERR ILDSREGVRV SQLSENGVTS LPTREDISFM  180
NPQRVFSSMS FVNPPGSQRV FPFNNEMRFM PSFENIRRES LKQTYGADFT DNRSLVINNA  240
NSFALRSSFV HEHRPSISSY LKTDMGSAGP AWTGSLSSSV PMNDRASTVG DFENGNSLSG  300
SGSLPTLQGV AVSSDKGAEA NTTSTKKKVS SDDWEPSEPF KASFTIPPYI LPSSDALYDP  360
FTDIENLGDR PLNDSLSSKG EHARKSSCQQ KDGDSASGPQ ARDCKNDDKS SSCSQNQHQE  420
TVARSLEAHG VVEGVATSVV DQNDTATPSK EISSATAAEN RVVLKRIKPA GHDSWHRSDG  480
SSYKKTKKSD EIDGEVRSDA GMKVMRLFRT AVVETIKEML KPLWREGRLT KDVHNMIVKK  540
AAEKVVGAAV QFHQVPTDTE SVDQYLGLSG TRIVKLVEGY VEKYGKP

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.44117	0.0	flower\| leaf\| seed\| vegetative tissue

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	186505117	0.0
Expression Atlas	AT2G33835	-
AtGenExpress	AT2G33835	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in root and shoot apices and vasculature. {ECO:0000269\|PubMed:16291783}.

Functional Description ? help Back to Top
Source	Description
TAIR	Encodes a zinc finger domain containing protein that is expressed in the shoot/root apex and vasculature, and acts with FRI to repress flowering.FES1 mutants in a Col(FRI+) background will flower early under inductive conditions.
UniProt	Transcriptional activator involved in the FRIGIDA-mediated vernalization pathway, but not in the autonomous flowering pathway. Acts cooperatively with FRI (FRIGIDA) or FRL1 (FRIGIDA-LIKE 1) to promote FLC (FLOWERING LOCUS C) expression. Required for the stabilization of the FRI-C complex. {ECO:0000269\|PubMed:16291783, ECO:0000269\|PubMed:21282526}.

Function -- GeneRIF ? help Back to Top
Epistasis analysis between FES1, FRI and FRIGIDA-LIKE 1 (FRL1), indicates that these genes do not function in a linear pathway, but instead act cooperatively to promote the expression of FLC. [PMID: 16291783]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G33835.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source	Target Gene (A: Activate/R: Repress)
ATRM	AT5G10140(A)

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G33835

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK228866	0.0	AK228866.1 Arabidopsis thaliana mRNA for zinc finger (CCCH type) protein - like, clone: RAFL16-19-E15.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_850221.1	0.0	Zinc finger C-x8-C-x5-C-x3-H type family protein
Swissprot	Q84VG7	0.0	FES1_ARATH; Protein FRIGIDA-ESSENTIAL 1
TrEMBL	A0A178VSR1	0.0	A0A178VSR1_ARATH; FES1
STRING	AT2G33835.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM13468	15	21
Representative plant	OGRP7281	7	9

Link Out ? help Back to Top
Phytozome	AT2G33835.1
Entrez Gene	817951
iHOP	AT2G33835
wikigenes	AT2G33835

Publications ? help Back to Top
Xiao YL,Malik M,Whitelaw CA,Town CD Cloning and sequencing of cDNAs for hypothetical genes from chromosome 2 of Arabidopsis. Plant Physiol., 2002. 130(4): p. 2118-28 [PMID:12481096] Schmitz RJ,Hong L,Michaels S,Amasino RM FRIGIDA-ESSENTIAL 1 interacts genetically with FRIGIDA and FRIGIDA-LIKE 1 to promote the winter-annual habit of Arabidopsis thaliana. Development, 2005. 132(24): p. 5471-8 [PMID:16291783] Kim S,Choi K,Park C,Hwang HJ,Lee I SUPPRESSOR OF FRIGIDA4, encoding a C2H2-Type zinc finger protein, represses flowering by transcriptional activation of Arabidopsis FLOWERING LOCUS C. Plant Cell, 2006. 18(11): p. 2985-98 [PMID:17138694] Proveniers M,Rutjens B,Brand M,Smeekens S The Arabidopsis TALE homeobox gene ATH1 controls floral competency through positive regulation of FLC. Plant J., 2007. 52(5): p. 899-913 [PMID:17908157] Wang D, et al. Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice. BMC Genomics, 2008. 9: p. 44 [PMID:18221561] Choi K, et al. The FRIGIDA complex activates transcription of FLC, a strong flowering repressor in Arabidopsis, by recruiting chromatin modification factors. Plant Cell, 2011. 23(1): p. 289-303 [PMID:21282526] Ding L,Kim SY,Michaels SD FLOWERING LOCUS C EXPRESSOR family proteins regulate FLOWERING LOCUS C expression in both winter-annual and rapid-cycling Arabidopsis. Plant Physiol., 2013. 163(1): p. 243-52 [PMID:23899645] Jin J, et al. An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors. Mol. Biol. Evol., 2015. 32(7): p. 1767-73 [PMID:25750178]