PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT2G31230.1

Common Name

ATERF15, ERF093, ERF15, ERF-15, F16D14.7

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 243aa MW: 27055.7 Da PI: 4.8236

Description

ethylene-responsive element binding factor 15

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G31230.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	54.6	2.7e-17	86	134	3	54
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkle 54 y+GVr ++ +g+++AeIrd + ng r++lg+f+ aeeAa a+++a+ + + AT2G31230.1 86 YRGVRKRP-WGKFAAEIRDSTRNG--IRVWLGTFDKAEEAALAYDQAAFATK 134 9*****.******44465..*******************98765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	21.733	85	143	IPR001471	AP2/ERF domain
SMART	SM00380	2.2E-35	85	149	IPR001471	AP2/ERF domain
Pfam	PF00847	1.9E-11	85	132	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.9E-29	85	144	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.1E-10	86	97	IPR001471	AP2/ERF domain
CDD	cd00018	1.46E-28	86	144	No hit	No description
SuperFamily	SSF54171	1.96E-21	86	145	IPR016177	DNA-binding domain
PRINTS	PR00367	4.1E-10	109	125	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006952	Biological Process	defense response
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0010200	Biological Process	response to chitin
GO:0005634	Cellular Component	nucleus
GO:0009507	Cellular Component	chloroplast
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000293	anatomy	guard cell
PO:0009005	anatomy	root
PO:0009047	anatomy	stem

Sequence ? help Back to Top
Protein Sequence Length: 243 aa Download sequence Send to blast
MEYSQSSMYS SPSSWSSSQE SLLWNESCFL DQSSEPQAFF CPNYDYSDDF FSFESPEMMI 60 KEEIQNGDVS NSEEEEKVGI DEERSYRGVR KRPWGKFAAE IRDSTRNGIR VWLGTFDKAE 120 EAALAYDQAA FATKGSLATL NFPVEVVRES LKKMENVNLH DGGSPVMALK RKHSLRNRPR 180 GKKRSSSSSS SSSNSSSCSS SSSTSSTSRS SSKQSVVKQE SGTLVVFEDL GAEYLEQLLM 240 SSC

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	4e-27	84	146	1	63	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.28356	0.0	flower\| root

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	264083_at	0.0
Expression Atlas	AT2G31230	-
AtGenExpress	AT2G31230	-
ATTED-II	AT2G31230	-

Functional Description ? help Back to Top
Source	Description
TAIR	encodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 18 members in this subfamily including ATERF-1, ATERF-2, AND ATERF-5.
UniProt	May act as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:11950980}.

Function -- GeneRIF ? help Back to Top
Data indicate that the overexpression (OX) lines with high AtERF15 (At2g31230) expression levels exhibited minor growth retardation during early seedling growth. [PMID: 25253450]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00286	DAP	27203113	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G31230.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Weakly induced by Pseudomonas syringae tomato (avirulent avrRpt2 strain), but also by mock inoculation. {ECO:0000269\|PubMed:11950980}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- Hormone ? help Back to Top
Source	Hormone
AHD	ethylene

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G31230

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC006593	0.0	AC006593.5 Arabidopsis thaliana chromosome 2 clone F16D14 map nga361, complete sequence.
GenBank	AY070443	0.0	AY070443.1 Arabidopsis thaliana putative ethylene reponse factor AP2 domain transcription factor (At2g31230) mRNA, complete cds.
GenBank	AY096563	0.0	AY096563.1 Arabidopsis thaliana putative ethylene reponse factor AP2 domain transcription factor (At2g31230) mRNA, complete cds.
GenBank	CP002685	0.0	CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_850162.1	1e-177	ethylene-responsive element binding factor 15
Swissprot	Q8VYM0	1e-178	ERF93_ARATH; Ethylene-responsive transcription factor 15
TrEMBL	A0A178VV98	1e-139	A0A178VV98_ARATH; ERF15
STRING	AT2G31230.1	1e-176	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM3990	18	59
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT2G31230.1
Entrez Gene	817680
iHOP	AT2G31230
wikigenes	AT2G31230

Publications ? help Back to Top
Fujimoto SY,Ohta M,Usui A,Shinshi H,Ohme-Takagi M Arabidopsis ethylene-responsive element binding factors act as transcriptional activators or repressors of GCC box-mediated gene expression. Plant Cell, 2000. 12(3): p. 393-404 [PMID:10715325] Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] O Identification of Arabidopsis ethylene-responsive element binding factors with distinct induction kinetics after pathogen infection. Plant Physiol., 2002. 128(4): p. 1313-22 [PMID:11950980] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Hoth S, et al. Monitoring genome-wide changes in gene expression in response to endogenous cytokinin reveals targets in Arabidopsis thaliana. FEBS Lett., 2003. 554(3): p. 373-80 [PMID:14623097] Kleffmann T, et al. The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions. Curr. Biol., 2004. 14(5): p. 354-62 [PMID:15028209] Hass C, et al. The response regulator 2 mediates ethylene signalling and hormone signal integration in Arabidopsis. EMBO J., 2004. 23(16): p. 3290-302 [PMID:15282545] Wang J, et al. Genomewide nonadditive gene regulation in Arabidopsis allotetraploids. Genetics, 2006. 172(1): p. 507-17 [PMID:16172500] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Ko JH,Yang SH,Han KH Upregulation of an Arabidopsis RING-H2 gene, XERICO, confers drought tolerance through increased abscisic acid biosynthesis. Plant J., 2006. 47(3): p. 343-55 [PMID:16792696] AbuQamar S, et al. Expression profiling and mutant analysis reveals complex regulatory networks involved in Arabidopsis response to Botrytis infection. Plant J., 2006. 48(1): p. 28-44 [PMID:16925600] Libault M,Wan J,Czechowski T,Udvardi M,Stacey G Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor. Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11 [PMID:17722694] Wang Z, et al. Identification and characterization of COI1-dependent transcription factor genes involved in JA-mediated response to wounding in Arabidopsis plants. Plant Cell Rep., 2008. 27(1): p. 125-35 [PMID:17786451] Pré M, et al. The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense. Plant Physiol., 2008. 147(3): p. 1347-57 [PMID:18467450] Ascencio-Ib Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. Plant Physiol., 2008. 148(1): p. 436-54 [PMID:18650403] MEDIATOR25 acts as an integrative hub for the regulation of jasmonate-responsive gene expression in Arabidopsis. Plant Physiol., 2012. 160(1): p. 541-55 [PMID:22822211] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Lee SB,Lee SJ,Kim SY AtERF15 is a positive regulator of ABA response. Plant Cell Rep., 2015. 34(1): p. 71-81 [PMID:25253450] Zhang H, et al. Arabidopsis AtERF15 positively regulates immunity against Pseudomonas syringae pv. tomato DC3000 and Botrytis cinerea. Front Plant Sci, 2015. 6: p. 686 [PMID:26388886] Riechmann JL,Meyerowitz EM The AP2/EREBP family of plant transcription factors. Biol. Chem., 1998. 379(6): p. 633-46 [PMID:9687012]