PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT2G27050.1

Common Name

AtEIL1, EIL1, T20P8.10

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

EIL

Protein Properties

Length: 584aa MW: 66495.4 Da PI: 6.0554

Description

ETHYLENE-INSENSITIVE3-like 1

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G27050.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	EIN3	517	8e-158	49	431	1	354
XXXXXXXXXXXXXXXXXXXXXXX..XXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS EIN3 1 eelkkrmwkdqmllkrlkerkkqlledkeaatgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpvegasdsLraWWkek 98 +el+krmw+d+m+lkrlke++ + + ke ++ +k+++s+eqarrkkmsraQDgiLkYMlk+mevc+aqGfvYgiipekgkpv+gasd+Lr+WWk+k AT2G27050.1 49 DELEKRMWRDKMRLKRLKEQQSK-C--KEG-VDGSKQRQSQEQARRKKMSRAQDGILKYMLKMMEVCKAQGFVYGIIPEKGKPVTGASDNLREWWKDK 142 79****************997.5..787.9999*********************************************************** PP XXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH---S--HHHHHHT--TT--.---- CS EIN3 99 vefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWWPtGkelwwgelglskdqgtppyk 196 v+fdrngpaai+kyq++n+i++g++++++ ++h+l+elqDTtlgSLLsalmqhcdppqrrfplekgv+pPWWP+G+e+ww++lgl+++qg+ppyk AT2G27050.1 143 VRFDRNGPAAIAKYQSENNISGGSNDCNSLVGPTPHTLQELQDTTLGSLLSALMQHCDPPQRRFPLEKGVSPPWWPNGNEEWWPQLGLPNEQGPPPYK 240 ************************99**************************************************************** PP -GGG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXXX..XX...XXXXXXXXXXXXXXXXXXXX.XXX CS EIN3 197 kphdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsah..ss...slrkqspkvtlsceqkedve.gkk 288 kphdlkkawkv+vLtavikhmsp+i++ir+l+rqsk+lqdkm+akes+++l+++nqee +++++++ ++ s++ +s ++ +++ +++dve +k AT2G27050.1 241 KPHDLKKAWKVGVLTAVIKHMSPDIAKIRKLVRQSKCLQDKMTAKESATWLAIINQEEVVARELYPEscPPlssSSSLGSGSLLINDCSEYDVEgFEK 338 ***************************************************************65225535555************9899 PP XXX.XXXXXXXXXX...........................XXXXXXXXXXXXXXXXXXXXX......XXXXXXX.XXXXXXXXXXXXXXXXX CS EIN3 289 eskikhvqavktta...........................gfpvvrkrkkkpsesakvsskevsrtcqssqfrgsetelifadknsisqney 354 e++ +v+++k + +++++rkrk++++ + +v+++++ +tc++ q+++s+++l+f+d++s++++++ AT2G27050.1 339 EQHGFDVEERKPEIvmmhplasfgvakmqhfpikeevattvNLEFTRKRKQNNDMNVMVMDRSAGYTCENGQCPHSKMNLGFQDRSSRDNHQM 431 999999999999889**************************************************************************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04873	3.9E-130	49	298	No hit	No description
Gene3D	G3DSA:1.10.3180.10	3.2E-75	173	308	IPR023278	Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamily	SSF116768	9.29E-62	177	301	IPR023278	Ethylene insensitive 3-like protein, DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009723	Biological Process	response to ethylene
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0042742	Biological Process	defense response to bacterium
GO:0071281	Biological Process	cellular response to iron ion
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0005515	Molecular Function	protein binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000037	anatomy	shoot apex
PO:0000084	anatomy	plant sperm cell
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025195	anatomy	pollen tube cell
PO:0025281	anatomy	pollen
PO:0001016	developmental stage	L mature pollen stage
PO:0001017	developmental stage	M germinated pollen stage
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 584 aa Download sequence Send to blast
MMMFNEMGMY GNMDFFSSST SLDVCPLPQA EQEPVVEDVD YTDDEMDVDE LEKRMWRDKM 60 RLKRLKEQQS KCKEGVDGSK QRQSQEQARR KKMSRAQDGI LKYMLKMMEV CKAQGFVYGI 120 IPEKGKPVTG ASDNLREWWK DKVRFDRNGP AAIAKYQSEN NISGGSNDCN SLVGPTPHTL 180 QELQDTTLGS LLSALMQHCD PPQRRFPLEK GVSPPWWPNG NEEWWPQLGL PNEQGPPPYK 240 KPHDLKKAWK VGVLTAVIKH MSPDIAKIRK LVRQSKCLQD KMTAKESATW LAIINQEEVV 300 ARELYPESCP PLSSSSSLGS GSLLINDCSE YDVEGFEKEQ HGFDVEERKP EIVMMHPLAS 360 FGVAKMQHFP IKEEVATTVN LEFTRKRKQN NDMNVMVMDR SAGYTCENGQ CPHSKMNLGF 420 QDRSSRDNHQ MVCPYRDNRL AYGASKFHMG GMKLVVPQQP VQPIDLSGVG VPENGQKMIT 480 ELMAMYDRNV QSNQTPPTLM ENQSMVIDAK AAQNQQLNFN SGNQMFMQQG TNNGVNNRFQ 540 MVFDSTPFDM AAFDYRDDWQ TGAMEGMGKQ QQQQQQQQDV SIWF

Sequence ? help Back to Top

Protein Sequence Length: 584 aa Download sequence Send to blast

MMMFNEMGMY GNMDFFSSST SLDVCPLPQA EQEPVVEDVD YTDDEMDVDE LEKRMWRDKM  60
RLKRLKEQQS KCKEGVDGSK QRQSQEQARR KKMSRAQDGI LKYMLKMMEV CKAQGFVYGI  120
IPEKGKPVTG ASDNLREWWK DKVRFDRNGP AAIAKYQSEN NISGGSNDCN SLVGPTPHTL  180
QELQDTTLGS LLSALMQHCD PPQRRFPLEK GVSPPWWPNG NEEWWPQLGL PNEQGPPPYK  240
KPHDLKKAWK VGVLTAVIKH MSPDIAKIRK LVRQSKCLQD KMTAKESATW LAIINQEEVV  300
ARELYPESCP PLSSSSSLGS GSLLINDCSE YDVEGFEKEQ HGFDVEERKP EIVMMHPLAS  360
FGVAKMQHFP IKEEVATTVN LEFTRKRKQN NDMNVMVMDR SAGYTCENGQ CPHSKMNLGF  420
QDRSSRDNHQ MVCPYRDNRL AYGASKFHMG GMKLVVPQQP VQPIDLSGVG VPENGQKMIT  480
ELMAMYDRNV QSNQTPPTLM ENQSMVIDAK AAQNQQLNFN SGNQMFMQQG TNNGVNNRFQ  540
MVFDSTPFDM AAFDYRDDWQ TGAMEGMGKQ QQQQQQQQDV SIWF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4zds_A	2e-85	176	308	2	134	Protein ETHYLENE INSENSITIVE 3
4zds_B	2e-85	176	308	2	134	Protein ETHYLENE INSENSITIVE 3
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	383	388	TRKRKQ

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.10809	0.0	root\| vegetative tissue

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	145360373	0.0
Genevisible	266302_at	0.0
Expression Atlas	AT2G27050	-
AtGenExpress	AT2G27050	-
ATTED-II	AT2G27050	-

Functional Description ? help Back to Top
Source	Description
TAIR	ethylene-insensitive3-like1 (EIL1)
UniProt	Probable transcription factor acting as a positive regulator in the ethylene response pathway. Could bind the primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter. {ECO:0000269\|PubMed:9215635, ECO:0000269\|PubMed:9851977}.

Function -- GeneRIF ? help Back to Top
Transcription factor EIL1 is required for the second phase but not the first phase of growth inhibition by ethylene in Arabidopsis seedling hypocotyls. [PMID: 15466219] Light induced regulation of gene expression involves stabilization of EIL1 protein. [PMID: 17011517] Data provide evidence that EIN3/EIL1 directly target SID2 to downregulate PAMP defenses. [PMID: 19717619] our studies demonstrate that ethylene similarly regulates EIN3 and EIL1, the two master transcription factors coordinating myriad ethylene responses, and clarify that EIN2 but not MKK9 is required for ethylene-induced EIN3/EIL1 stabilization [PMID: 20647342] EIN3/EIL1 physically interact with FIT, are required for full FIT accumulation, and contribute to full FIT downstream target gene expression. [PMID: 21586684] identify EIN3/EIL1 as a key integration node whose activation requires both jasmonate and ethylene signaling as a common mechanism to integrate diverse signaling pathways in the regulation of plant development and defense [PMID: 21737749] Photo-oxidative stress may increase upon iron deficiency, which is prevented by expression of EIN3/EIL1. [PMID: 22212120] High salinity induces EIN3 and EIL1 protein accumulation and regulates EIL1 dependent gene network. [PMID: 25330213] these data suggest the detailed mechanism of DNA recognition by EIN3 and provide an in-depth view at molecular level for the transcriptional regulation mediated by EIN3. [PMID: 26352699] EIN3/EIL1 and RHD6/RSL1 coordinately enhance root hair initiation by selectively regulating a subset of core root hair genes. [PMID: 29233944]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G27050.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source	Target Gene (A: Activate/R: Repress)
ATRM	AT1G74710(R), AT3G23240(A), AT4G27440(A), AT5G54190(A)

Regulation -- Hormone ? help Back to Top
Source	Hormone
AHD	ethylene

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT2G28160, AT4G17880, AT5G46760, AT1G32640
IntAct	Search Q9SLH0

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G27050

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC005623	0.0	AC005623.3 Arabidopsis thaliana chromosome 2 clone T20P8 map B68, complete sequence.
GenBank	AY065191	0.0	AY065191.1 Arabidopsis thaliana ethylene-insensitive3-like1 (EIL1) (At2g27050; T20P8.10) mRNA, complete cds.
GenBank	BT003344	0.0	BT003344.1 Arabidopsis thaliana ethylene-insensitive3-like1 (EIL1) (At2g27050) mRNA, complete cds.
GenBank	CP002685	0.0	CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_180273.1	0.0	ETHYLENE-INSENSITIVE3-like 1
Swissprot	Q9SLH0	0.0	EIL1_ARATH; ETHYLENE INSENSITIVE 3-like 1 protein
TrEMBL	A0A178VP15	0.0	A0A178VP15_ARATH; EIL1
STRING	AT2G27050.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2135	28	79
Representative plant	OGRP563	16	82

Link Out ? help Back to Top
Phytozome	AT2G27050.1
Entrez Gene	817247
iHOP	AT2G27050
wikigenes	AT2G27050

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Waki K,Shibuya K,Yoshioka T,Hashiba T,Satoh S Cloning of a cDNA encoding EIN3-like protein (DC-EIL1) and decrease in its mRNA level during senescence in carnation flower tissues. J. Exp. Bot., 2001. 52(355): p. 377-9 [PMID:11283184] Tieman DM,Ciardi JA,Taylor MG,Klee HJ Members of the tomato LeEIL (EIN3-like) gene family are functionally redundant and regulate ethylene responses throughout plant development. Plant J., 2001. 26(1): p. 47-58 [PMID:11359609] Wang KL,Li H,Ecker JR Ethylene biosynthesis and signaling networks. Plant Cell, 2002. 14 Suppl: p. S131-51 [PMID:12045274] Alonso JM, et al. Five components of the ethylene-response pathway identified in a screen for weak ethylene-insensitive mutants in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2003. 100(5): p. 2992-7 [PMID:12606727] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Guo H,Ecker JR Plant responses to ethylene gas are mediated by SCF(EBF1/EBF2)-dependent proteolysis of EIN3 transcription factor. Cell, 2003. 115(6): p. 667-77 [PMID:14675532] Potuschak T, et al. EIN3-dependent regulation of plant ethylene hormone signaling by two arabidopsis F box proteins: EBF1 and EBF2. Cell, 2003. 115(6): p. 679-89 [PMID:14675533] Chen G,Alexander L,Grierson D Constitutive expression of EIL-like transcription factor partially restores ripening in the ethylene-insensitive Nr tomato mutant. J. Exp. Bot., 2004. 55(402): p. 1491-7 [PMID:15181103] Binder BM,Mortimore LA,Stepanova AN,Ecker JR,Bleecker AB Short-term growth responses to ethylene in Arabidopsis seedlings are EIN3/EIL1 independent. Plant Physiol., 2004. 136(2): p. 2921-7 [PMID:15466219] Chang C,Bleecker AB Ethylene biology. More than a gas. Plant Physiol., 2004. 136(2): p. 2895-9 [PMID:15489282] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Barry CS,Giovannoni JJ Ripening in the tomato Green-ripe mutant is inhibited by ectopic expression of a protein that disrupts ethylene signaling. Proc. Natl. Acad. Sci. U.S.A., 2006. 103(20): p. 7923-8 [PMID:16682641] Lee JH,Deng XW,Kim WT Possible role of light in the maintenance of EIN3/EIL1 stability in Arabidopsis seedlings. Biochem. Biophys. Res. Commun., 2006. 350(2): p. 484-91 [PMID:17011517] Binder BM, et al. The Arabidopsis EIN3 binding F-Box proteins EBF1 and EBF2 have distinct but overlapping roles in ethylene signaling. Plant Cell, 2007. 19(2): p. 509-23 [PMID:17307926] Ascencio-Ib Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. Plant Physiol., 2008. 148(1): p. 436-54 [PMID:18650403] Wang Y, et al. Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. Plant Physiol., 2008. 148(3): p. 1201-11 [PMID:18775970] Chen H, et al. ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 repress SALICYLIC ACID INDUCTION DEFICIENT2 expression to negatively regulate plant innate immunity in Arabidopsis. Plant Cell, 2009. 21(8): p. 2527-40 [PMID:19717619] Zhong S, et al. EIN3/EIL1 cooperate with PIF1 to prevent photo-oxidation and to promote greening of Arabidopsis seedlings. Proc. Natl. Acad. Sci. U.S.A., 2009. 106(50): p. 21431-6 [PMID:19948955] Camehl I, et al. Ethylene signalling and ethylene-targeted transcription factors are required to balance beneficial and nonbeneficial traits in the symbiosis between the endophytic fungus Piriformospora indica and Arabidopsis thaliana. New Phytol., 2010. 185(4): p. 1062-73 [PMID:20085621] Garc Ethylene and nitric oxide involvement in the up-regulation of key genes related to iron acquisition and homeostasis in Arabidopsis. J. Exp. Bot., 2010. 61(14): p. 3885-99 [PMID:20627899] An F, et al. Ethylene-induced stabilization of ETHYLENE INSENSITIVE3 and EIN3-LIKE1 is mediated by proteasomal degradation of EIN3 binding F-box 1 and 2 that requires EIN2 in Arabidopsis. Plant Cell, 2010. 22(7): p. 2384-401 [PMID:20647342] Boutrot F, et al. Direct transcriptional control of the Arabidopsis immune receptor FLS2 by the ethylene-dependent transcription factors EIN3 and EIL1. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(32): p. 14502-7 [PMID:20663954] Elrouby N,Coupland G Proteome-wide screens for small ubiquitin-like modifier (SUMO) substrates identify Arabidopsis proteins implicated in diverse biological processes. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(40): p. 17415-20 [PMID:20855607] Jeong SW, et al. Ethylene suppression of sugar-induced anthocyanin pigmentation in Arabidopsis. Plant Physiol., 2010. 154(3): p. 1514-31 [PMID:20876338] Lingam S, et al. Interaction between the bHLH transcription factor FIT and ETHYLENE INSENSITIVE3/ETHYLENE INSENSITIVE3-LIKE1 reveals molecular linkage between the regulation of iron acquisition and ethylene signaling in Arabidopsis. Plant Cell, 2011. 23(5): p. 1815-29 [PMID:21586684] Lei G, et al. EIN2 regulates salt stress response and interacts with a MA3 domain-containing protein ECIP1 in Arabidopsis. Plant Cell Environ., 2011. 34(10): p. 1678-92 [PMID:21631530] Zhu Z, et al. Derepression of ethylene-stabilized transcription factors (EIN3/EIL1) mediates jasmonate and ethylene signaling synergy in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2011. 108(30): p. 12539-44 [PMID:21737749] Zhang L, et al. An AP2 domain-containing gene, ESE1, targeted by the ethylene signaling component EIN3 is important for the salt response in Arabidopsis. Plant Physiol., 2011. 157(2): p. 854-65 [PMID:21832142] Bauer P,Blondet E Transcriptome analysis of ein3 eil1 mutants in response to iron deficiency. Plant Signal Behav, 2011. 6(11): p. 1669-71 [PMID:22212120] An F, et al. Coordinated regulation of apical hook development by gibberellins and ethylene in etiolated Arabidopsis seedlings. Cell Res., 2012. 22(5): p. 915-27 [PMID:22349459] Zhao Y, et al. Arabidopsis RAP2.2 plays an important role in plant resistance to Botrytis cinerea and ethylene responses. New Phytol., 2012. 195(2): p. 450-60 [PMID:22530619] Shi Y, et al. Ethylene signaling negatively regulates freezing tolerance by repressing expression of CBF and type-A ARR genes in Arabidopsis. Plant Cell, 2012. 24(6): p. 2578-95 [PMID:22706288] Meinke DW A survey of dominant mutations in Arabidopsis thaliana. Trends Plant Sci., 2013. 18(2): p. 84-91 [PMID:22995285] Zheng D, et al. The nitrate transporter NRT2.1 functions in the ethylene response to nitrate deficiency in Arabidopsis. Plant Cell Environ., 2013. 36(7): p. 1328-37 [PMID:23305042] Kim HG, et al. GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling. Plant Physiol., 2013. 163(4): p. 1776-91 [PMID:24170202] Song S, et al. Interaction between MYC2 and ETHYLENE INSENSITIVE3 modulates antagonism between jasmonate and ethylene signaling in Arabidopsis. Plant Cell, 2014. 26(1): p. 263-79 [PMID:24399301] Zhang GB,Yi HY,Gong JM The Arabidopsis ethylene/jasmonic acid-NRT signaling module coordinates nitrate reallocation and the trade-off between growth and environmental adaptation. Plant Cell, 2014. 26(10): p. 3984-98 [PMID:25326291] Peng J, et al. Salt-induced stabilization of EIN3/EIL1 confers salinity tolerance by deterring ROS accumulation in Arabidopsis. PLoS Genet., 2014. 10(10): p. e1004664 [PMID:25330213] Wang J, et al. Arabidopsis ROOT HAIR DEFECTIVE3 is involved in nitrogen starvation-induced anthocyanin accumulation. J Integr Plant Biol, 2015. 57(8): p. 708-21 [PMID:25494721] Jin J, et al. An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors. Mol. Biol. Evol., 2015. 32(7): p. 1767-73 [PMID:25750178] Song J, et al. Biochemical and Structural Insights into the Mechanism of DNA Recognition by Arabidopsis ETHYLENE INSENSITIVE3. PLoS ONE, 2015. 10(9): p. e0137439 [PMID:26352699] Qing D, et al. Quantitative and Functional Phosphoproteomic Analysis Reveals that Ethylene Regulates Water Transport via the C-Terminal Phosphorylation of Aquaporin PIP2;1 in Arabidopsis. Mol Plant, 2016. 9(1): p. 158-174 [PMID:26476206] Poulios S,Vlachonasios KE Synergistic action of histone acetyltransferase GCN5 and receptor CLAVATA1 negatively affects ethylene responses in Arabidopsis thaliana. J. Exp. Bot., 2016. 67(3): p. 905-18 [PMID:26596766] Shen X,Li Y,Pan Y,Zhong S Activation of HLS1 by Mechanical Stress via Ethylene-Stabilized EIN3 Is Crucial for Seedling Soil Emergence. Front Plant Sci, 2016. 7: p. 1571 [PMID:27822221] Abozeid A, et al. Ethylene Improves Root System Development under Cadmium Stress by Modulating Superoxide Anion Concentration in Arabidopsis thaliana. Front Plant Sci, 2017. 8: p. 253 [PMID:28286514] Feng Y, et al. Ethylene promotes root hair growth through coordinated EIN3/EIL1 and RHD6/RSL1 activity in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(52): p. 13834-13839 [PMID:29233944] Harkey AF, et al. Identification of Transcriptional and Receptor Networks That Control Root Responses to Ethylene. Plant Physiol., 2018. 176(3): p. 2095-2118 [PMID:29259106] Chao Q, et al. Activation of the ethylene gas response pathway in Arabidopsis by the nuclear protein ETHYLENE-INSENSITIVE3 and related proteins. Cell, 1997. 89(7): p. 1133-44 [PMID:9215635] Solano R,Stepanova A,Chao Q,Ecker JR Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE-RESPONSE-FACTOR1. Genes Dev., 1998. 12(23): p. 3703-14 [PMID:9851977]