PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT2G25900.2

Common Name

ATCTH, ATTZF1, F17H15.7

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

C3H

Protein Properties

Length: 315aa MW: 35464.7 Da PI: 7.434

Description

C3H family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G25900.2	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-CCCH	25.6	2.1e-08	135	155	5	26
--SGGGGTS--TTTTT-SS-SS CS zf-CCCH 5 lCrffartGtCkyGdrCkFaHg 26 C+ f++ G C++Gd+C F+Hg AT2G25900.2 135 ACPEFRK-GSCRRGDSCEFSHG 155 7****.***********9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00356	1.3E-5	130	156	IPR000571	Zinc finger, CCCH-type
PROSITE profile	PS50103	13.469	131	157	IPR000571	Zinc finger, CCCH-type
Pfam	PF00642	1.8E-6	135	155	IPR000571	Zinc finger, CCCH-type
Gene3D	G3DSA:4.10.1000.10	4.2E-4	135	157	IPR000571	Zinc finger, CCCH-type
PROSITE profile	PS50103	6.296	165	189	IPR000571	Zinc finger, CCCH-type
SMART	SM00356	27	165	188	IPR000571	Zinc finger, CCCH-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0061157	Biological Process	mRNA destabilization
GO:0005737	Cellular Component	cytoplasm
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0003727	Molecular Function	single-stranded RNA binding
GO:0046872	Molecular Function	metal ion binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000025	anatomy	root tip
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0009062	anatomy	gynoecium
PO:0009066	anatomy	anther
PO:0020003	anatomy	plant ovule
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 315 aa Download sequence Send to blast
MMIGENKNRP HPTIHIPQWD QINDPTATIS SPFSSVNLNS VNDYPHSPSP YLDSFASLFR 60 YLPSNELTND SDSSSGDESS PLTDSFSSDE FRIYEFKIRR CARGRSHDWT ECPFAHPGEK 120 ARRRDPRKFH YSGTACPEFR KGSCRRGDSC EFSHGVFECW LHPSRYRTQP CKDGTSCRRR 180 ICFFAHTTEQ LRVLPCSLDP DLGFFSGLAT SPTSILVSPS FSPPSESPPL SPSTGELIAS 240 MRKMQLNGGG CSWSSPMRSA VRLPFSSSLR PIQAATWPRI REFEIEEAPA MEFVESGKEL 300 RAEMYARLSR ENSLG

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.23916	0.0	bud\| cell culture\| flower\| seed\| silique\| vegetative tissue

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	334184471	0.0
Genevisible	266656_at	0.0
Expression Atlas	AT2G25900	-
AtGenExpress	AT2G25900	-
ATTED-II	AT2G25900	-

Functional Description ? help Back to Top
Source	Description
TAIR	putative Cys3His zinc finger protein (ATCTH) mRNA, complete

Function -- GeneRIF ? help Back to Top
This study suggested that, Since TZF1 can bind both DNA and RNA in vitro, it raises the possibility that TZF1 might be involved in DNA and/or RNA regulation. [PMID: 19897605] AtTZF1 may serve as a regulator connecting sugar, ABA, GA and peptide hormone responses. [PMID: 21223390] AtTZF1 fusion proteins could not exert obvious transcriptional activity in a maize protoplast transient expression system. [PMID: 21455027] AtTZF1 triggers the decay of AU-rich elements-containing mRNAs.TFZ1 protein zinc finger integrity is vital for RNA binding. [PMID: 24635033] Overexpression of AtZFP1 enhances salt tolerance by maintaining ionic balance and limiting oxidative and osmotic stress. [PMID: 25074582]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G25900.2

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G25900

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC005395	0.0	AC005395.3 Arabidopsis thaliana chromosome 2 clone F17H15 map B68, complete sequence.
GenBank	AF370590	0.0	AF370590.1 Arabidopsis thaliana putative CCCH-type zinc finger protein (At2g25900; F17H15.7) mRNA, complete cds.
GenBank	AF375403	0.0	AF375403.1 Arabidopsis thaliana At2g25900/F17H15.7 mRNA, complete cds.
GenBank	AK117272	0.0	AK117272.1 Arabidopsis thaliana At2g25900 mRNA for putative Cys3His zinc finger protein ATCTH (ATCTH), complete cds, clone: RAFL16-82-I02.
GenBank	AY129468	0.0	AY129468.1 Arabidopsis thaliana At2g25900/F17H15.7 mRNA, complete cds.
GenBank	CP002685	0.0	CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001189604.1	0.0	Zinc finger C-x8-C-x5-C-x3-H type family protein
Refseq	NP_180161.1	0.0	Zinc finger C-x8-C-x5-C-x3-H type family protein
Swissprot	O82307	0.0	C3H23_ARATH; Zinc finger CCCH domain-containing protein 23
TrEMBL	A0A178VMZ5	0.0	A0A178VMZ5_ARATH; ATTZF1
STRING	AT2G25900.1	0.0	(Arabidopsis thaliana)

Link Out ? help Back to Top
Phytozome	AT2G25900.2
Entrez Gene	817131
iHOP	AT2G25900
wikigenes	AT2G25900

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Seki M, et al. Functional annotation of a full-length Arabidopsis cDNA collection. Science, 2002. 296(5565): p. 141-5 [PMID:11910074] Cartieaux F, et al. Transcriptome analysis of Arabidopsis colonized by a plant-growth promoting rhizobacterium reveals a general effect on disease resistance. Plant J., 2003. 36(2): p. 177-88 [PMID:14535883] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Kasukabe Y, et al. Overexpression of spermidine synthase enhances tolerance to multiple environmental stresses and up-regulates the expression of various stress-regulated genes in transgenic Arabidopsis thaliana. Plant Cell Physiol., 2004. 45(6): p. 712-22 [PMID:15215506] Contento AL,Kim SJ,Bassham DC Transcriptome profiling of the response of Arabidopsis suspension culture cells to Suc starvation. Plant Physiol., 2004. 135(4): p. 2330-47 [PMID:15310832] Tran RK, et al. Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis. Genome Biol., 2005. 6(11): p. R90 [PMID:16277745] Coupe SA, et al. Systemic signalling of environmental cues in Arabidopsis leaves. J. Exp. Bot., 2006. 57(2): p. 329-41 [PMID:16330523] Delaney KJ, et al. Calmodulin interacts with and regulates the RNA-binding activity of an Arabidopsis polyadenylation factor subunit. Plant Physiol., 2006. 140(4): p. 1507-21 [PMID:16500995] Diet A, et al. The Arabidopsis root hair cell wall formation mutant lrx1 is suppressed by mutations in the RHM1 gene encoding a UDP-L-rhamnose synthase. Plant Cell, 2006. 18(7): p. 1630-41 [PMID:16766693] Little D,Gouhier-Darimont C,Bruessow F,Reymond P Oviposition by pierid butterflies triggers defense responses in Arabidopsis. Plant Physiol., 2007. 143(2): p. 784-800 [PMID:17142483] Osuna D, et al. Temporal responses of transcripts, enzyme activities and metabolites after adding sucrose to carbon-deprived Arabidopsis seedlings. Plant J., 2007. 49(3): p. 463-91 [PMID:17217462] Alves-Ferreira M, et al. Global expression profiling applied to the analysis of Arabidopsis stamen development. Plant Physiol., 2007. 145(3): p. 747-62 [PMID:17905860] Wang D, et al. Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice. BMC Genomics, 2008. 9: p. 44 [PMID:18221561] Soitamo AJ,Piippo M,Allahverdiyeva Y,Battchikova N,Aro EM Light has a specific role in modulating Arabidopsis gene expression at low temperature. BMC Plant Biol., 2008. 8: p. 13 [PMID:18230142] Usadel B, et al. Global transcript levels respond to small changes of the carbon status during progressive exhaustion of carbohydrates in Arabidopsis rosettes. Plant Physiol., 2008. 146(4): p. 1834-61 [PMID:18305208] Ascencio-Ib Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. Plant Physiol., 2008. 148(1): p. 436-54 [PMID:18650403] Skinner DJ,Gasser CS Expression-based discovery of candidate ovule development regulators through transcriptional profiling of ovule mutants. BMC Plant Biol., 2009. 9: p. 29 [PMID:19291320] Pomeranz MC, et al. The Arabidopsis tandem zinc finger protein AtTZF1 traffics between the nucleus and cytoplasmic foci and binds both DNA and RNA. Plant Physiol., 2010. 152(1): p. 151-65 [PMID:19897605] Pomeranz M,Lin PC,Finer J,Jang JC AtTZF gene family localizes to cytoplasmic foci. Plant Signal Behav, 2010. 5(2): p. 190-2 [PMID:20173417] Lin PC, et al. The Arabidopsis tandem zinc finger protein AtTZF1 affects ABA- and GA-mediated growth, stress and gene expression responses. Plant J., 2011. 65(2): p. 253-68 [PMID:21223390] Pomeranz M,Zhang L,Finer J,Jang JC Can AtTZF1 act as a transcriptional activator or repressor in plants? Plant Signal Behav, 2011. 6(5): p. 719-22 [PMID:21455027] Bogamuwa S,Jang JC The Arabidopsis tandem CCCH zinc finger proteins AtTZF4, 5 and 6 are involved in light-, abscisic acid- and gibberellic acid-mediated regulation of seed germination. Plant Cell Environ., 2013. 36(8): p. 1507-19 [PMID:23421766] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Qu J,Kang SG,Wang W,Musier-Forsyth K,Jang JC The Arabidopsis thaliana tandem zinc finger 1 (AtTZF1) protein in RNA binding and decay. Plant J., 2014. 78(3): p. 452-67 [PMID:24635033] Han G, et al. The CCCH zinc finger protein gene AtZFP1 improves salt resistance in Arabidopsis thaliana. Plant Mol. Biol., 2014. 86(3): p. 237-53 [PMID:25074582]