PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT2G22760.1

Common Name

BHLH19, EN26, T30L20.2

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 295aa MW: 33787.1 Da PI: 6.0821

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G22760.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	33	1.1e-10	119	165	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 h +Er+RR+++ ++f L llP + kK +K++iL A+ +k+Lq AT2G22760.1 119 EHVLAERKRREKLSEKFIALSALLPGL-----KKADKVTILDDAISRMKQLQ 165 5899*********************.....9****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	14.615	115	164	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.4E-8	119	165	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.7E-16	119	181	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	6.28E-16	119	181	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.17E-10	120	169	No hit	No description
SMART	SM00353	6.2E-14	121	170	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000005	anatomy	cultured plant cell
PO:0000013	anatomy	cauline leaf
PO:0000033	anatomy	fruit valve
PO:0000036	anatomy	leaf vascular system
PO:0000051	anatomy	petiole epidermis
PO:0000056	anatomy	flower bud
PO:0000112	anatomy	shoot axis epidermis
PO:0000293	anatomy	guard cell
PO:0004006	anatomy	mesophyll cell
PO:0004707	anatomy	fruit dehiscence zone
PO:0006016	anatomy	leaf epidermis
PO:0006036	anatomy	root epidermis
PO:0006040	anatomy	sepal epidermis
PO:0006504	anatomy	leaf trichome
PO:0009005	anatomy	root
PO:0009047	anatomy	stem
PO:0009049	anatomy	inflorescence
PO:0009053	anatomy	peduncle
PO:0009081	anatomy	inflorescence branch
PO:0020127	anatomy	primary root
PO:0020128	anatomy	leaf margin

Sequence ? help Back to Top
Protein Sequence Length: 295 aa Download sequence Send to blast
MDEDFFLPDF SLVDIDFDFN IYEENNLSPD ESLSNSRRAD QSSKFDHQMH FECLREKPKA 60 AVKPMMKINN KQQLISFDFS SNVISSPAAE EIIMDKLVGR GTKRKTCSHG TRSPVLAKEH 120 VLAERKRREK LSEKFIALSA LLPGLKKADK VTILDDAISR MKQLQEQLRT LKEEKEATRQ 180 MESMILVKKS KVFFDEEPNL SCSPSVHIEF DQALPEIEAK ISQNDILIRI LCEKSKGCMI 240 NILNTIENFQ LRIENSIVLP FGDSTLDITV LAQMDKDFSM SILKDLVRNL RLAMV

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	123	128	ERKRRE
2	124	129	RKRREK

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	266455_at	0.0
Expression Atlas	AT2G22760	-
AtGenExpress	AT2G22760	-
ATTED-II	AT2G22760	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots and leaves. {ECO:0000269\|PubMed:12679534}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G22760.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cold treatment. {ECO:0000269\|PubMed:12679534}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Interaction ? help Back to Top
Source	Intact With
IntAct	Search Q1PF16

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G22760

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	DQ446550	0.0	DQ446550.1 Arabidopsis thaliana clone pENTR221-At2g22760 basic helix-loop-helix family protein (At2g22760) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_179861.2	0.0	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Swissprot	Q1PF16	0.0	BH019_ARATH; Transcription factor bHLH19
TrEMBL	C0SV56	0.0	C0SV56_ARATH; Uncharacterized protein At2g22760 (Fragment)
STRING	AT2G22760.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM492	27	146
Representative plant	OGRP656	15	73

Link Out ? help Back to Top
Phytozome	AT2G22760.1
Entrez Gene	816806
iHOP	AT2G22760
wikigenes	AT2G22760

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Heim MA, et al. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol., 2003. 20(5): p. 735-47 [PMID:12679534] Toledo-Ortiz G,Huq E,Quail PH The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell, 2003. 15(8): p. 1749-70 [PMID:12897250] Bailey PC, et al. Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana. Plant Cell, 2003. 15(11): p. 2497-502 [PMID:14600211] Matsushima R,Fukao Y,Nishimura M,Hara-Nishimura I NAI1 gene encodes a basic-helix-loop-helix-type putative transcription factor that regulates the formation of an endoplasmic reticulum-derived structure, the ER body. Plant Cell, 2004. 16(6): p. 1536-49 [PMID:15155889] Ma S,Gong Q,Bohnert HJ Dissecting salt stress pathways. J. Exp. Bot., 2006. 57(5): p. 1097-107 [PMID:16510518] Truman W,de Zabala MT,Grant M Type III effectors orchestrate a complex interplay between transcriptional networks to modify basal defence responses during pathogenesis and resistance. Plant J., 2006. 46(1): p. 14-33 [PMID:16553893] Underwood BA,Vanderhaeghen R,Whitford R,Town CD,Hilson P Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations. Plant Biotechnol. J., 2006. 4(3): p. 317-24 [PMID:17147637] Colinas J,Schmidler SC,Bohrer G,Iordanov B,Benfey PN Intergenic and genic sequence lengths have opposite relationships with respect to gene expression. PLoS ONE, 2008. 3(11): p. e3670 [PMID:18989364] Jaspers P, et al. Unequally redundant RCD1 and SRO1 mediate stress and developmental responses and interact with transcription factors. Plant J., 2009. 60(2): p. 268-79 [PMID:19548978] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Efroni I, et al. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev. Cell, 2013. 24(4): p. 438-45 [PMID:23449474] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]