PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT2G14760.1

Common Name

BHLH84, F26C24.10

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 328aa MW: 36500.3 Da PI: 4.7651

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G14760.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.8	2.5e-10	253	293	10	55
HHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 10 rrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 r+RR+riN+++ L+ l+P+ +K++ +++Le+Av+Y+k Lq AT2G14760.1 253 RKRRERINERLRILQHLVPNG-----TKVDISTMLEEAVQYVKFLQ 293 9****************97.....8****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.186	243	292	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	4.45E-14	244	309	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.9E-12	248	302	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.0E-11	249	298	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	4.35E-11	252	297	No hit	No description
Pfam	PF00010	1.2E-7	253	293	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009555	Biological Process	pollen development
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 328 aa Download sequence Send to blast
MEAMGEWSTG LGGIYTEEAD FMNQLLASYE QPCGGSSSET TATLTAYHHQ GSQWNGGFCF 60 SQESSSYSGY CAAMPRQEED NNGMEDATIN TNLYLVGEET SECDATEYSG KSLLPLETVA 120 ENHDHSMLQP ENSLTTTTDE KMFNQCESSK KRTRATTTDK NKRANKARRS QKCVEMSGEN 180 ENSGEEEYTE KAAGKRKTKP LKPQKTCCSD DESNGGDTFL SKEDGEDSKA LNLNGKTRAS 240 RGAATDPQSL YARKRRERIN ERLRILQHLV PNGTKVDIST MLEEAVQYVK FLQLQIKLLS 300 SDDLWMYAPI AYNGMDIGLD LKLNALTR

Expression -- Microarray ? help Back to Top
Source	ID
Expression Atlas	AT2G14760
AtGenExpress	AT2G14760

Function -- GeneRIF ? help Back to Top
we report the characterization of bHLH84, which funtions as a transcriptional activator that enhances the autoimmunity of NLR mutant snc1 (suppressor of npr1-1, constitutive 1) and confers enhanced immunity in wild-type backgrounds when overexpressed [PMID: 25144198]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G14760.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G14760

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ577584	0.0	AJ577584.1 Arabidopsis thaliana mRNA for putative bHLH084 transcription factor (bHLH084 gene).
GenBank	DQ446497	0.0	DQ446497.1 Arabidopsis thaliana clone pENTR221-At2g14760 basic helix-loop-helix protein/bHLH protein (At2g14760) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_179083.2	0.0	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Swissprot	Q7XHI9	0.0	BH084_ARATH; Transcription factor bHLH84
TrEMBL	A0A178VRL7	0.0	A0A178VRL7_ARATH; Uncharacterized protein
STRING	fgenesh2_kg.3__3067__AT2G14760.1	0.0	(Arabidopsis lyrata)

Link Out ? help Back to Top
Phytozome	AT2G14760.1
Entrez Gene	815964
iHOP	AT2G14760
wikigenes	AT2G14760

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Heim MA, et al. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol., 2003. 20(5): p. 735-47 [PMID:12679534] Toledo-Ortiz G,Huq E,Quail PH The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell, 2003. 15(8): p. 1749-70 [PMID:12897250] Bailey PC, et al. Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana. Plant Cell, 2003. 15(11): p. 2497-502 [PMID:14600211] Underwood BA,Vanderhaeghen R,Whitford R,Town CD,Hilson P Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations. Plant Biotechnol. J., 2006. 4(3): p. 317-24 [PMID:17147637] Reňák D,Dupl'áková N,Honys D Wide-scale screening of T-DNA lines for transcription factor genes affecting male gametophyte development in Arabidopsis. Sex. Plant Reprod., 2012. 25(1): p. 39-60 [PMID:22101548] Xu F, et al. NLR-associating transcription factor bHLH84 and its paralogs function redundantly in plant immunity. PLoS Pathog., 2014. 10(8): p. e1004312 [PMID:25144198]