PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT1G75390.1

Common Name

AtbZIP44, bZIP44, F1B16.8

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bZIP

Protein Properties

Length: 173aa MW: 19073.2 Da PI: 6.9467

Description

basic leucine-zipper 44

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT1G75390.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	38.2	3e-12	41	81	5	45
CHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 5 krerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaL 45 ++ +rkq+NRe+ArrsR RK++ ++ L+ v L +eN + AT1G75390.1 41 RKRKRKQSNRESARRSRMRKQKHLDDLTAQVTHLRKENAQI 81 5789**********************************865 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.20.5.170	5.0E-11	36	86	No hit	No description
SMART	SM00338	1.2E-16	37	101	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	10.622	39	102	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	1.63E-11	41	93	No hit	No description
Pfam	PF00170	8.6E-10	41	81	IPR004827	Basic-leucine zipper domain
CDD	cd14702	2.31E-21	42	92	No hit	No description
PROSITE pattern	PS00036	0	44	59	IPR004827	Basic-leucine zipper domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009845	Biological Process	seed germination
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046982	Molecular Function	protein heterodimerization activity

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000293	anatomy	guard cell
PO:0007057	developmental stage	seed germination stage

Sequence ? help Back to Top
Protein Sequence Length: 173 aa Download sequence Send to blast
MNNKTEMGSS TSGNCSSVST TGLANSGSES DLRQRDLIDE RKRKRKQSNR ESARRSRMRK 60 QKHLDDLTAQ VTHLRKENAQ IVAGIAVTTQ HYVTIEAEND ILRAQVLELN HRLQSLNEIV 120 DFVESSSSGF GMETGQGLFD GGLFDGVMNP MNLGFYNQPI MASASTAGDV FNC

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	40	45	RKRKRK
2	40	61	RKRKRKQSNRESARRSRMRKQK
3	53	60	RRSRMRKQ

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.16252	0.0	floral meristem\| flower\| leaf\| root\| seed\| silique

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	186495615	0.0
Genevisible	261114_at	0.0
Expression Atlas	AT1G75390	-
AtGenExpress	AT1G75390	-
ATTED-II	AT1G75390	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in the micropylar endosperm and radicle tip in early germinating seeds. {ECO:0000269\|PubMed:23461773}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds to the DNA G-box motif 5'-CACGTG-3' of MAN7 promoter. Involved in the positive regulation of seed germination through MAN7 gene activation. MAN7 is required for both, loosening of the micropylar endosperm, and rupture of the seed coat in germinating seeds. {ECO:0000269\|PubMed:23461773}.

Function -- GeneRIF ? help Back to Top
Data indicate that the expression of AtMAN7 gene (At5g66460) gene drastically reduced in the knock-out lines of AtbZIP44 (At1g75390). [PMID: 23461773]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00239	DAP	27203113	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT1G75390.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Interaction ? help Back to Top
Source	Intact With
IntAct	Search C0Z2L5

Phenotype -- Disruption Phenotype ? help Back to Top
Source	Description
UniProt	DISRUPTION PHENOTYPE: No visible phenotype under normal growth conditions, but seeds have decreased germination speed after imbibition, without affecting overall germination rate. {ECO:0000269\|PubMed:23461773}.

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT1G75390

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC023754	0.0	AC023754.3 Arabidopsis thaliana chromosome I BAC F1B16 genomic sequence, complete sequence.
GenBank	AK318829	0.0	AK318829.1 Arabidopsis thaliana AT1G75390 mRNA, complete cds, clone: RAFL14-51-H21.
GenBank	AK318991	0.0	AK318991.1 Arabidopsis thaliana AT1G75390 mRNA, complete cds, clone: RAFL21-81-N15.
GenBank	CP002684	0.0	CP002684.1 Arabidopsis thaliana chromosome 1 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_177672.2	1e-126	basic leucine-zipper 44
Swissprot	C0Z2L5	1e-127	BZP44_ARATH; bZIP transcription factor 44
TrEMBL	A0A178W597	1e-125	A0A178W597_ARATH; Uncharacterized protein
STRING	AT1G75390.1	1e-126	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM501	28	154
Representative plant	OGRP551	16	78

Link Out ? help Back to Top
Phytozome	AT1G75390.1
Entrez Gene	843875
iHOP	AT1G75390
wikigenes	AT1G75390

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Jakoby M, et al. bZIP transcription factors in Arabidopsis. Trends Plant Sci., 2002. 7(3): p. 106-11 [PMID:11906833] Boisson B,Giglione C,Meinnel T Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote. J. Biol. Chem., 2003. 278(44): p. 43418-29 [PMID:12912986] Dal Bosco C, et al. Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. J. Biol. Chem., 2004. 279(2): p. 1060-9 [PMID:14576160] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Wiese A,Elzinga N,Wobbes B,Smeekens S A conserved upstream open reading frame mediates sucrose-induced repression of translation. Plant Cell, 2004. 16(7): p. 1717-29 [PMID:15208401] Deppmann CD, et al. Dimerization specificity of all 67 B-ZIP motifs in Arabidopsis thaliana: a comparison to Homo sapiens B-ZIP motifs. Nucleic Acids Res., 2004. 32(11): p. 3435-45 [PMID:15226410] Wang XJ,Cao XL,Hong Y Isolation and characterization of flower-specific transcripts in Acacia mangium. Tree Physiol., 2005. 25(2): p. 167-78 [PMID:15574398] Pischke MS,Huttlin EL,Hegeman AD,Sussman MR A transcriptome-based characterization of habituation in plant tissue culture. Plant Physiol., 2006. 140(4): p. 1255-78 [PMID:16489130] Ehlert A, et al. Two-hybrid protein-protein interaction analysis in Arabidopsis protoplasts: establishment of a heterodimerization map of group C and group S bZIP transcription factors. Plant J., 2006. 46(5): p. 890-900 [PMID:16709202] Deppmann CD,Alvania RS,Taparowsky EJ Cross-species annotation of basic leucine zipper factor interactions: Insight into the evolution of closed interaction networks. Mol. Biol. Evol., 2006. 23(8): p. 1480-92 [PMID:16731568] Hayden CA,Jorgensen RA Identification of novel conserved peptide uORF homology groups in Arabidopsis and rice reveals ancient eukaryotic origin of select groups and preferential association with transcription factor-encoding genes. BMC Biol., 2007. 5: p. 32 [PMID:17663791] Weltmeier F, et al. Expression patterns within the Arabidopsis C/S1 bZIP transcription factor network: availability of heterodimerization partners controls gene expression during stress response and development. Plant Mol. Biol., 2009. 69(1-2): p. 107-19 [PMID:18841482] Kang SG,Price J,Lin PC,Hong JC,Jang JC The arabidopsis bZIP1 transcription factor is involved in sugar signaling, protein networking, and DNA binding. Mol Plant, 2010. 3(2): p. 361-73 [PMID:20080816] Brady SM, et al. A stele-enriched gene regulatory network in the Arabidopsis root. Mol. Syst. Biol., 2011. 7: p. 459 [PMID:21245844] Iglesias-Fern Arabidopsis thaliana bZIP44: a transcription factor affecting seed germination and expression of the mannanase-encoding gene AtMAN7. Plant J., 2013. 74(5): p. 767-80 [PMID:23461773] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Pedrotti L, et al. Snf1-RELATED KINASE1-Controlled C/S1-bZIP Signaling Activates Alternative Mitochondrial Metabolic Pathways to Ensure Plant Survival in Extended Darkness. Plant Cell, 2018. 30(2): p. 495-509 [PMID:29348240]