PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G61660.1
Common NameBHLH112, EN64, T13M11.1
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 393aa    MW: 43041.2 Da    PI: 6.5085
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G61660.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH20.21.1e-062813191154
                  HHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
          HLH  11 rRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                   R +++++ +  L++l+ +      +K + a++L++A+eYIk L
  AT1G61660.1 281 VRKENLRDQITSLQQLVSPF-----GKTDTASVLQEAIEYIKFL 319
                  5778999**********998.....8****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088811.935270319IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.46E-6280323No hitNo description
Gene3DG3DSA:4.10.280.106.6E-9280330IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003530.0071280325IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.22E-11280335IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0042631Biological Processcellular response to water deprivation
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0045944Biological Processpositive regulation of transcription from RNA polymerase II promoter
GO:0071215Biological Processcellular response to abscisic acid stimulus
GO:0071472Biological Processcellular response to salt stress
GO:2000214Biological Processregulation of proline metabolic process
GO:2000377Biological Processregulation of reactive oxygen species metabolic process
GO:0005634Cellular Componentnucleus
GO:0001046Molecular Functioncore promoter sequence-specific DNA binding
GO:0001228Molecular Functiontranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0005515Molecular Functionprotein binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 393 aa     Download sequence    Send to blast
MAEEFKATAS ICGGGGGAWW NSPRSVMSPS DHFLSPCFGA AITSNDFSSQ ENHLKSRMTC  60
TDNNNIVFGQ READSDSGGS TVTMDSTLQM MGLGFSSNCS SDWNQTILQE DLNSSFIRSS  120
QDQDHGQGFL STTTSPYILN PACSSSPSTS SSSSLIRTFY DPEPSPYNFV STTSGSINDP  180
QLSWANKTNP HHQVAYGLIN SFSNNANSRP FWNSSSTTNL NNTTPSNFVT TPQIISTRLE  240
DKTKNLKTRA QSESLKRAKD NESAAKKPRV TTPSPLPTFK VRKENLRDQI TSLQQLVSPF  300
GKTDTASVLQ EAIEYIKFLH DQVTVLSTPY MKQGASNQQQ QQISGKSKSQ DENENHELRG  360
HGLCLVPISS TFPVANETTA DFWTPTFGGN NFR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.228500.0root
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible265034_at0.0
Expression AtlasAT1G61660-
AtGenExpressAT1G61660-
ATTED-IIAT1G61660-
Function -- GeneRIF ? help Back to Top
  1. the functional role of a basic helix-loop-helix transcription factor from Arabidopsis, AtbHLH112, in response to abiotic stress, was investigated.
    [PMID: 25827016]
  2. These results suggested that the rice gene HLH068 and the Arabidopsis gene HLH112 share partially redundant functions in the regulation of abiotic stress responses but have opposite functions to control flowering in Arabidopsis.[HLH112]
    [PMID: 28631168]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G61660.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
IntActSearch Q94JL3
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G61660
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF3806490.0AF380649.1 Arabidopsis thaliana At1g61660/T13M11_21 mRNA, complete cds.
GenBankAY1130720.0AY113072.1 Arabidopsis thaliana At1g61660/T13M11_21 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001322872.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
RefseqNP_564782.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ94JL30.0BH112_ARATH; Transcription factor bHLH112
TrEMBLA0A178WKI70.0A0A178WKI7_ARATH; Uncharacterized protein
STRINGAT1G61660.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80622636
Representative plantOGRP31351129
Publications ? help Back to Top
  1. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  2. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  3. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. Guan Y,Nothnagel EA
    Binding of arabinogalactan proteins by Yariv phenylglycoside triggers wound-like responses in Arabidopsis cell cultures.
    Plant Physiol., 2004. 135(3): p. 1346-66
    [PMID:15235117]
  6. Wong CE, et al.
    Transcriptional profiling implicates novel interactions between abiotic stress and hormonal responses in Thellungiella, a close relative of Arabidopsis.
    Plant Physiol., 2006. 140(4): p. 1437-50
    [PMID:16500996]
  7. Ditt RF, et al.
    The Arabidopsis thaliana transcriptome in response to Agrobacterium tumefaciens.
    Mol. Plant Microbe Interact., 2006. 19(6): p. 665-81
    [PMID:16776300]
  8. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  9. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  10. Brady SM, et al.
    A stele-enriched gene regulatory network in the Arabidopsis root.
    Mol. Syst. Biol., 2011. 7: p. 459
    [PMID:21245844]
  11. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  12. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  13. Liu Y, et al.
    Arabidopsis AtbHLH112 regulates the expression of genes involved in abiotic stress tolerance by binding to their E-box and GCG-box motifs.
    New Phytol., 2015. 207(3): p. 692-709
    [PMID:25827016]
  14. Chen HC, et al.
    The function of OsbHLH068 is partially redundant with its homolog, AtbHLH112, in the regulation of the salt stress response but has opposite functions to control flowering in Arabidopsis.
    Plant Mol. Biol., 2017. 94(4-5): p. 531-548
    [PMID:28631168]