PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT1G34790.1

Common Name

F11O6.15, TT1, WIP1

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

C2H2

Protein Properties

Length: 303aa MW: 34511.9 Da PI: 7.5482

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT1G34790.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.9	8.6e-06	145	164	1	20
EEETTTTEEESSHHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrHi 20 ++C+ C k+F+r nL+ H+ AT1G34790.1 145 FSCHVCFKTFNRYNNLQMHM 164 89*****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	3.19E-5	127	167	No hit	No description
PROSITE profile	PS50157	10.055	145	172	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	3.5E-4	145	164	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	147	167	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009813	Biological Process	flavonoid biosynthetic process
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0009010	anatomy	seed

Sequence ? help Back to Top
Protein Sequence Length: 303 aa Download sequence Send to blast
MESPPLYEIS SSSSSEKPRH HFQSLDLFPN LNQNSCINNT LIEPLPLIDR INLNSNLDLN 60 PNPLYAEEGE QEEEEEEEED REVDVDLHIG LPGFGKPSND AKQLKKRNGK EIATYDAGKG 120 IENELSGKAY WIPAPEQILI GFTHFSCHVC FKTFNRYNNL QMHMWGHGSQ YRKGPESLKG 180 TQPRAMLGIP CYCCVEGCRN HIDHPRSKPL KDFRTLQTHY KRKHGHKPFS CRLCGKLLAV 240 KGDWRTHEKN CGKRWVCVCG SDFKHKRSLK DHVKAFGSGH GPYPTGLFEE QASNSSVSET 300 LFF

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.39652	0.0	flower

Expression -- Microarray ? help Back to Top
Source	ID
Expression Atlas	AT1G34790
AtGenExpress	AT1G34790

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Developing ovules and young seeds. {ECO:0000269\|PubMed:11782451}.
Uniprot	TISSUE SPECIFICITY: Restricted to the endothelium, the innermost cell layer of the seed coat and detected to a lesser extent in the other cell layers of the testa. {ECO:0000269\|PubMed:11782451}.

Functional Description ? help Back to Top
Source	Description
TAIR	Encodes a zinc finger protein; involved in photomorphogenesis, flavonoid biosynthesis, flower and seed development.
UniProt	May act as a transcriptional regulator involved in the differentiation of young endothelium. Altered differentiation results in incompetence for pigments synthesis and the lack of condensed tannins in the seed coat (PubMed:21477081). Plays a role in the regulatory network controlling flavonoid accumulation in endothelium cells during seed development (PubMed:21477081). {ECO:0000269\|PubMed:11782451, ECO:0000269\|PubMed:21477081}.

Function -- GeneRIF ? help Back to Top
TT1 controls early and late steps of flavonoid biosynthesis in the endothelium of Arabidopsis thaliana seeds. [PMID: 21477081]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT1G34790.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source	Target Gene (A: Activate/R: Repress)
ATRM	AT1G61720(A)

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT1G34790, AT1G56650

Phenotype -- Disruption Phenotype ? help Back to Top
Source	Description
UniProt	DISRUPTION PHENOTYPE: Lack of flavanoid pigment accumulation in the seed coat endothelium (transparent testa phenotype). {ECO:0000269\|PubMed:21477081}.

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT1G34790

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF190298	0.0	AF190298.1 Arabidopsis thaliana ecotype Columbia transparent testa 1 (TT1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_174737.2	0.0	C2H2 and C2HC zinc fingers superfamily protein
Swissprot	Q8VWG3	0.0	TT1_ARATH; Protein TRANSPARENT TESTA 1
TrEMBL	A0A178WC09	0.0	A0A178WC09_ARATH; WIP1
STRING	AT1G34790.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM239	28	237
Representative plant	OGRP410	15	97

Link Out ? help Back to Top
Phytozome	AT1G34790.1
Entrez Gene	840386
iHOP	AT1G34790
wikigenes	AT1G34790

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Sagasser M,Lu GH,Hahlbrock K,Weisshaar B A. thaliana TRANSPARENT TESTA 1 is involved in seed coat development and defines the WIP subfamily of plant zinc finger proteins. Genes Dev., 2002. 16(1): p. 138-49 [PMID:11782451] Nesi N, et al. The TRANSPARENT TESTA16 locus encodes the ARABIDOPSIS BSISTER MADS domain protein and is required for proper development and pigmentation of the seed coat. Plant Cell, 2002. 14(10): p. 2463-79 [PMID:12368498] Debeaujon I, et al. Proanthocyanidin-accumulating cells in Arabidopsis testa: regulation of differentiation and role in seed development. Plant Cell, 2003. 15(11): p. 2514-31 [PMID:14555692] Buer CS,Djordjevic MA Architectural phenotypes in the transparent testa mutants of Arabidopsis thaliana. J. Exp. Bot., 2009. 60(3): p. 751-63 [PMID:19129166] Nesi N, et al. The promoter of the Arabidopsis thaliana BAN gene is active in proanthocyanidin-accumulating cells of the Brassica napus seed coat. Plant Cell Rep., 2009. 28(4): p. 601-17 [PMID:19153740] Appelhagen I, et al. Weird fingers: functional analysis of WIP domain proteins. FEBS Lett., 2010. 584(14): p. 3116-22 [PMID:20541552] Appelhagen I, et al. TRANSPARENT TESTA1 interacts with R2R3-MYB factors and affects early and late steps of flavonoid biosynthesis in the endothelium of Arabidopsis thaliana seeds. Plant J., 2011. 67(3): p. 406-19 [PMID:21477081] Jia L, et al. Proanthocyanidins inhibit seed germination by maintaining a high level of abscisic acid in Arabidopsis thaliana. J Integr Plant Biol, 2012. 54(9): p. 663-73 [PMID:22765383] Jin J, et al. An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors. Mol. Biol. Evol., 2015. 32(7): p. 1767-73 [PMID:25750178] Zhou X,Groves NR,Meier I Plant nuclear shape is independently determined by the SUN-WIP-WIT2-myosin XI-i complex and CRWN1. Nucleus, 2015. 6(2): p. 144-53 [PMID:25759303] Lian J, et al. Silencing of BnTT1 family genes affects seed flavonoid biosynthesis and alters seed fatty acid composition in Brassica napus. Plant Sci., 2017. 254: p. 32-47 [PMID:27964783] Shirley BW, et al. Analysis of Arabidopsis mutants deficient in flavonoid biosynthesis. Plant J., 1995. 8(5): p. 659-71 [PMID:8528278]