PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G22490.1
Common NameBHLH94, EN16, F12K8.16
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 304aa    MW: 34893.3 Da    PI: 6.969
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G22490.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH482.2e-15113164155
                  CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                  +r++h ++Er+RR+++N+ ++ Lr+l+P++   ++++ + a+i+  A++Y+k+L+
  AT1G22490.1 113 QRMTHIAVERNRRKQMNEYLAVLRSLMPSS---YAQRGDQASIVGGAINYVKELE 164
                  79****************************...*******************996 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000837.68E-13111168No hitNo description
SuperFamilySSF474591.83E-17112178IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.7E-14112166IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088816.196112163IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.6E-12113164IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.5E-10118169IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020100anatomyhypocotyl
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 304 aa     Download sequence    Send to blast
MPLEAVVYPQ DPFGYLSNCK DFMFHDLYSQ EEFVAQDTKN NIDKLGHEQS FVEQGKEDDH  60
QWRDYHQYPL LIPSLGEELG LTAIDVESHP PPQHRRKRRR TRNCKNKEEI ENQRMTHIAV  120
ERNRRKQMNE YLAVLRSLMP SSYAQRGDQA SIVGGAINYV KELEHILQSM EPKRTRTHDP  180
KGDKTSTSSL VGPFTDFFSF PQYSTKSSSD VPESSSSPAE IEVTVAESHA NIKIMTKKKP  240
RQLLKLITSL QSLRLTLLHL NVTTLHNSIL YSISVRVEEG SQLNTVDDIA TALNQTIRRI  300
QEET
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
19599RKRRR
295100RKRRRT
3113124RMTHIAVERNRR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.192470.0silique
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306878970.0
Genevisible261941_at0.0
Expression AtlasAT1G22490-
AtGenExpressAT1G22490-
ATTED-IIAT1G22490-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G22490.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G22490
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0882340.0AY088234.1 Arabidopsis thaliana clone 4596 mRNA, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_564171.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ9SK910.0BH094_ARATH; Transcription factor bHLH94
TrEMBLA0A1P8ANU60.0A0A1P8ANU6_ARATH; Basic helix-loop-helix (BHLH) DNA-binding superfamily protein
STRINGAT1G22490.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM111627102
Representative plantOGRP25315131
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  6. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  7. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]