PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT1G21910.1

Common Name

DREB26, ERF012, T26F17.14

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 230aa MW: 25476.2 Da PI: 7.7563

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT1G21910.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	56.6	6.6e-18	48	98	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ++ykGVr ++ +g+Wv+eIr p ++++r++lg++ tae Aa+a++ a ++l+g AT1G21910.1 48 KKYKGVRMRS-WGSWVSEIRAP---NQKTRIWLGSYSTAEAAARAYDVALLCLKG 98 59***998.******9...336**********************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	22.01	49	106	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	3.07E-20	49	108	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	1.9E-30	49	108	IPR001471	AP2/ERF domain
SMART	SM00380	1.6E-35	49	112	IPR001471	AP2/ERF domain
Pfam	PF00847	4.4E-11	49	98	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.4E-9	50	61	IPR001471	AP2/ERF domain
CDD	cd00018	8.02E-30	50	108	No hit	No description
PRINTS	PR00367	5.4E-9	72	88	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009751	Biological Process	response to salicylic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0034605	Biological Process	cellular response to heat
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0071497	Biological Process	cellular response to freezing
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000003	anatomy	whole plant
PO:0000013	anatomy	cauline leaf
PO:0000014	anatomy	rosette leaf
PO:0000037	anatomy	shoot apex
PO:0000056	anatomy	flower bud
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009001	anatomy	fruit
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009049	anatomy	inflorescence
PO:0009052	anatomy	flower pedicel
PO:0009066	anatomy	anther
PO:0020003	anatomy	plant ovule
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025281	anatomy	pollen
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007131	developmental stage	seedling development stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 230 aa Download sequence Send to blast
MVKQERKIQT SSTKKEMPLS SSPSSSSSSS SSSSSSSCKN KNKKSKIKKY KGVRMRSWGS 60 WVSEIRAPNQ KTRIWLGSYS TAEAAARAYD VALLCLKGPQ ANLNFPTSSS SHHLLDNLLD 120 ENTLLSPKSI QRVAAQAANS FNHFAPTSSA VSSPSDHDHH HDDGMQSLMG SFVDNHVSLM 180 DSTSSWYDDH NGMFLFDNGA PFNYSPQLNS TTMLDEYFYE DADIPLWSFN

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.41636	0.0	seed\| silique

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	260856_at	0.0
Expression Atlas	AT1G21910	-
AtGenExpress	AT1G21910	-
ATTED-II	AT1G21910	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed cotyledons, ovules and seeds of immature siliques. {ECO:0000269\|PubMed:21069430}.

Functional Description ? help Back to Top
Source	Description
TAIR	encodes a member of the DREB subfamily A-5 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 15 members in this subfamily including RAP2.1, RAP2.9 and RAP2.10.
UniProt	Transcriptional activator involved in the regulation of plant development and tolerance to abiotic stresses (PubMed:21069430). Involved in salt and osmotic stress response pathways. May be regulated by the stress-related genes RD29A, RD22, DREB1A or P5CS during stress response (PubMed:27137403). Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:21069430, ECO:0000269\|PubMed:27137403}.

Function -- GeneRIF ? help Back to Top
Data demonstrate that RAP2.6 (At1g43160), RAP2.6L (At5g13330), DREB 26 (At1g21910) and DREB19 (At2g38340) are transactivators, they exhibit tissue specific expression, and participate in developmental processes as well as biotic/abiotic stress signaling. [PMID: 21069430]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00156	DAP	27203113	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT1G21910.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by jasmonate (JA) and ethylene. Down-regulated by freezing and heat stresses. {ECO:0000269\|PubMed:21069430}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT1G21910

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC013482	0.0	AC013482.2 Genomic sequence for Arabidopsis thaliana BAC T26F17 from chromosome I, complete sequence.
GenBank	AK176679	0.0	AK176679.1 Arabidopsis thaliana mRNA for TINY like protein, complete cds, clone: RAFL25-22-A03.
GenBank	BT024616	0.0	BT024616.1 Arabidopsis thaliana At1g21910 mRNA, complete cds.
GenBank	CP002684	0.0	CP002684.1 Arabidopsis thaliana chromosome 1 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_173609.1	1e-169	Integrase-type DNA-binding superfamily protein
Swissprot	Q9SFE4	1e-170	ERF12_ARATH; Ethylene-responsive transcription factor ERF012
TrEMBL	A0A178W3Q9	1e-168	A0A178W3Q9_ARATH; DREB26
STRING	AT1G21910.1	1e-169	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2999	27	67
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT1G21910.1
Entrez Gene	838793
iHOP	AT1G21910
wikigenes	AT1G21910

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Dal Bosco C, et al. Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. J. Biol. Chem., 2004. 279(2): p. 1060-9 [PMID:14576160] Rizhsky L,Davletova S,Liang H,Mittler R The zinc finger protein Zat12 is required for cytosolic ascorbate peroxidase 1 expression during oxidative stress in Arabidopsis. J. Biol. Chem., 2004. 279(12): p. 11736-43 [PMID:14722088] Guan Y,Nothnagel EA Binding of arabinogalactan proteins by Yariv phenylglycoside triggers wound-like responses in Arabidopsis cell cultures. Plant Physiol., 2004. 135(3): p. 1346-66 [PMID:15235117] Wang R, et al. Genomic analysis of the nitrate response using a nitrate reductase-null mutant of Arabidopsis. Plant Physiol., 2004. 136(1): p. 2512-22 [PMID:15333754] Hilson P, et al. Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications. Genome Res., 2004. 14(10B): p. 2176-89 [PMID:15489341] Lee D,Polisensky DH,Braam J Genome-wide identification of touch- and darkness-regulated Arabidopsis genes: a focus on calmodulin-like and XTH genes. New Phytol., 2005. 165(2): p. 429-44 [PMID:15720654] Suzuki N, et al. Enhanced tolerance to environmental stress in transgenic plants expressing the transcriptional coactivator multiprotein bridging factor 1c. Plant Physiol., 2005. 139(3): p. 1313-22 [PMID:16244138] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Wagner R,Pfannschmidt T Eukaryotic transcription factors in plastids--Bioinformatic assessment and implications for the evolution of gene expression machineries in plants. Gene, 2006. 381: p. 62-70 [PMID:16934950] Lee J, et al. Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development. Plant Cell, 2007. 19(3): p. 731-49 [PMID:17337630] Sottosanto JB,Saranga Y,Blumwald E Impact of AtNHX1, a vacuolar Na+/H+ antiporter, upon gene expression during short- and long-term salt stress in Arabidopsis thaliana. BMC Plant Biol., 2007. 7: p. 18 [PMID:17411438] Kleine T,Kindgren P,Benedict C,Hendrickson L,Strand A Genome-wide gene expression analysis reveals a critical role for CRYPTOCHROME1 in the response of Arabidopsis to high irradiance. Plant Physiol., 2007. 144(3): p. 1391-406 [PMID:17478635] Ramel F, et al. Genome-wide interacting effects of sucrose and herbicide-mediated stress in Arabidopsis thaliana: novel insights into atrazine toxicity and sucrose-induced tolerance. BMC Genomics, 2007. 8: p. 450 [PMID:18053238] Ferreira FJ,Guo C,Coleman JR Reduction of plastid-localized carbonic anhydrase activity results in reduced Arabidopsis seedling survivorship. Plant Physiol., 2008. 147(2): p. 585-94 [PMID:18434607] Krishnaswamy SS, et al. Transcriptional profiling of pea ABR17 mediated changes in gene expression in Arabidopsis thaliana. BMC Plant Biol., 2008. 8: p. 91 [PMID:18783601] Krishnaswamy S,Verma S,Rahman MH,Kav NN Functional characterization of four APETALA2-family genes (RAP2.6, RAP2.6L, DREB19 and DREB26) in Arabidopsis. Plant Mol. Biol., 2011. 75(1-2): p. 107-27 [PMID:21069430] Gaudinier A, et al. Enhanced Y1H assays for Arabidopsis. Nat. Methods, 2011. 8(12): p. 1053-5 [PMID:22037706] Kazama D,Kurusu T,Mitsuda N,Ohme-Takagi M,Tada Y Involvement of elevated proline accumulation in enhanced osmotic stress tolerance in Arabidopsis conferred by chimeric repressor gene silencing technology. Plant Signal Behav, 2014. 9(3): p. e28211 [PMID:24614501] Kazama D, et al. Identification of Chimeric Repressors that Confer Salt and Osmotic Stress Tolerance in Arabidopsis. Plants (Basel), 2013. 2(4): p. 769-85 [PMID:27137403]