PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G12540.1
Common NameBHLH55, EN1, F5O11.28, T12C24.8
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 257aa    MW: 29100.2 Da    PI: 8.1004
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G12540.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH42.89.4e-1475127155
                  CHHHHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   1 rrrahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                  +r++h+e Er+RR++  s f  Lr llP+      ++K s a+ + +Av+YIk+Lq
  AT1G12540.1  75 KRAKHKELERQRRQENTSLFKILRYLLPSqY---IKGKRSSADHVLEAVNYIKDLQ 127
                  79***************************66...*********************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474591.19E-1471150IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.78E-1072131No hitNo description
PROSITE profilePS5088813.60574126IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.2E-1075145IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000104.4E-1175127IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003530.004680132IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006357Biological Processregulation of transcription from RNA polymerase II promoter
GO:0090575Cellular ComponentRNA polymerase II transcription factor complex
GO:0000977Molecular FunctionRNA polymerase II regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 257 aa     Download sequence    Send to blast
MNFPDSSLFT PNFAYENDLD FSSLITPSTR VSFQEPKPCN PVIHSAGIEN DGRQNCETTM  60
TLSEIMKGDD EPKNKRAKHK ELERQRRQEN TSLFKILRYL LPSQYIKGKR SSADHVLEAV  120
NYIKDLQKKI KEVSEKRDRI KRSITHPSSR GEFSIRSLAS STCSCVGDTN IAVVVRPCLI  180
GLEIVVSCCN RHESCLSSVL QLLAQEQCFN IVSCISTRLH QGFIHTIASE VEEGIEVYFS  240
ELQEKIIKIG TSRVTTR
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
17486KRAKHKELERQRR
2126141QKKIKEVSEKRDRIKR
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO3341825020.0
Expression AtlasAT1G12540-
AtGenExpressAT1G12540-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G12540.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By salicylic acid (SA). {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G12540
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4885890.0AF488589.1 Arabidopsis thaliana clone bHLH055 putative bHLH transcription factor mRNA, partial sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_172715.40.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ9LN950.0BH055_ARATH; Transcription factor bHLH55
TrEMBLA0A178W3V00.0A0A178W3V0_ARATH; Uncharacterized protein
STRINGAT1G12540.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM62281843
Representative plantOGRP1638838
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Abe H, et al.
    Arabidopsis AtMYC2 (bHLH) and AtMYB2 (MYB) function as transcriptional activators in abscisic acid signaling.
    Plant Cell, 2003. 15(1): p. 63-78
    [PMID:12509522]
  3. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  4. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  5. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  6. Wisman E, et al.
    Knock-out mutants from an En-1 mutagenized Arabidopsis thaliana population generate phenylpropanoid biosynthesis phenotypes.
    Proc. Natl. Acad. Sci. U.S.A., 1998. 95(21): p. 12432-7
    [PMID:9770503]