PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G10120.1
Common NameACE2, BHLH74, CIB4, EN90, T27I1.15
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 366aa    MW: 40151.6 Da    PI: 5.7896
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G10120.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH31.43.4e-10215263355
                  HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                   +h+ +Er RR++i +++  L+el+P +    +k   Ka +L + ++Y++sLq
  AT1G10120.1 215 NSHSLAERVRREKISERMRLLQELVPGC----NKITGKAVMLDEIINYVQSLQ 263
                  58**************************....999*****************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000832.43E-11210267No hitNo description
SuperFamilySSF474594.45E-17210280IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088815.485212262IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.108.7E-17213280IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.0E-7215263IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.6E-10218268IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009637Biological Processresponse to blue light
GO:0040008Biological Processregulation of growth
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 366 aa     Download sequence    Send to blast
MGGESNEGGE MGFKHGDDES GGISRVGITS MPLYAKADPF FSSADWDPVV NAAAAGFSSS  60
HYHPSMAMDN PGMSCFSHYQ PGSVSGFAAD MPASLLPFGD CGGGQIGHFL GSDKKGERLI  120
RAGESSHEDH HQVSDDAVLG ASPVGKRRLP EAESQWNKKA VEEFQEDPQR GNDQSQKKHK  180
NDQSKETVNK ESSQSEEAPK ENYIHMRARR GQATNSHSLA ERVRREKISE RMRLLQELVP  240
GCNKITGKAV MLDEIINYVQ SLQQQVEFLS MKLATVNPEI NIDIDRILAK DLLQSRDRNT  300
PTLGLNPFAG FQGNIPNLSA TTNPQYNPLP QTTLESELQN LYQMGFVSNP STMSSFSPNG  360
RLKPEL
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.433910.0flower| root| seed
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible264517_at0.0
Expression AtlasAT1G10120-
AtGenExpressAT1G10120-
ATTED-IIAT1G10120-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator involved in cell elongation. Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light (PubMed:24130508). {ECO:0000269|PubMed:23161888, ECO:0000269|PubMed:24130508}.
Function -- GeneRIF ? help Back to Top
  1. MIR396a-mediated bHLH74 repression helps regulate root growth in Arabidopsis seedlings.
    [PMID: 24793750]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00135DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G10120.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G10120
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2218060.0AK221806.1 Arabidopsis thaliana mRNA for bHLH transcription factor like protein, complete cds, clone: RAFL21-86-B04.
GenBankBT0126550.0BT012655.1 Arabidopsis thaliana At1g10120 gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001321212.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
RefseqNP_172483.40.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ6NKN90.0BH074_ARATH; Transcription factor bHLH74
TrEMBLD7KKM20.0D7KKM2_ARALL; Uncharacterized protein
STRINGAT1G10120.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM51962849
Representative plantOGRP5816313
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. Bae MS,Cho EJ,Choi EY,Park OK
    Analysis of the Arabidopsis nuclear proteome and its response to cold stress.
    Plant J., 2003. 36(5): p. 652-63
    [PMID:14617066]
  6. Kim MJ,Kim JK,Shin JS,Suh MC
    The SebHLH transcription factor mediates trans-activation of the SeFAD2 gene promoter through binding to E- and G-box elements.
    Plant Mol. Biol., 2007. 64(4): p. 453-66
    [PMID:17420955]
  7. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  8. Ikeda M,Fujiwara S,Mitsuda N,Ohme-Takagi M
    A triantagonistic basic helix-loop-helix system regulates cell elongation in Arabidopsis.
    Plant Cell, 2012. 24(11): p. 4483-97
    [PMID:23161888]
  9. Liu Y,Li X,Li K,Liu H,Lin C
    Multiple bHLH proteins form heterodimers to mediate CRY2-dependent regulation of flowering-time in Arabidopsis.
    PLoS Genet., 2013. 9(10): p. e1003861
    [PMID:24130508]
  10. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  11. Bao M, et al.
    miR396a-Mediated basic helix-loop-helix transcription factor bHLH74 repression acts as a regulator for root growth in Arabidopsis seedlings.
    Plant Cell Physiol., 2014. 55(7): p. 1343-53
    [PMID:24793750]