PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT1G04370.1

Common Name

ATERF14, ERF097, ERF14, ERF-14, F19P19.19

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 133aa MW: 14743 Da PI: 7.7475

Description

Ethylene-responsive element binding factor 14

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT1G04370.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	63.5	4.5e-20	19	69	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+++AeIrd ++ g r++lg+f+tae+Aa+a+++a+ +++g AT1G04370.1 19 KYRGVRRRP-WGKYAAEIRDSRKHG--ERVWLGTFDTAEDAARAYDRAAYSMRG 69 8******.******65443..***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.730.10	3.1E-32	19	79	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	9.81E-24	19	79	IPR016177	DNA-binding domain
CDD	cd00018	4.56E-18	19	78	No hit	No description
PROSITE profile	PS51032	23.947	19	77	IPR001471	AP2/ERF domain
SMART	SM00380	3.0E-35	19	83	IPR001471	AP2/ERF domain
Pfam	PF00847	2.5E-14	19	69	IPR001471	AP2/ERF domain
PRINTS	PR00367	8.8E-12	20	31	IPR001471	AP2/ERF domain
PRINTS	PR00367	8.8E-12	43	59	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006952	Biological Process	defense response
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 133 aa Download sequence Send to blast
MDQGGRSSGS GGGGAEQGKY RGVRRRPWGK YAAEIRDSRK HGERVWLGTF DTAEDAARAY 60 DRAAYSMRGK AAILNFPHEY NMGTGSSSTA ANSSSSSQQV FEFEYLDDSV LDELLEYGEN 120 YNKTHNINMG KRQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	6e-54	1	110	1	114	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	18390385	0.0
Expression Atlas	AT1G04370	-
AtGenExpress	AT1G04370	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Ubiquitously expressed after ethylene treatment. {ECO:0000269\|PubMed:11950980}.

Functional Description ? help Back to Top
Source	Description
TAIR	encodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 18 members in this subfamily including ATERF-1, ATERF-2, AND ATERF-5.
UniProt	Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269\|PubMed:11950980}.

Function -- GeneRIF ? help Back to Top
AtERF14 gene is important for ethylene responses and pathogen resistance. [AtERF14] [PMID: 17114278] ERF9 and ERF14 are involved in the interaction between Piriformospora and Arabidopsis. Inactivation of these genes diminishes the P. indica-induced growth promotion and activates the expression of the PATHOGENESIS-RELATED genes. [PMID: 20505369]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT1G04370.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains). Not affected by methyl jasmonate (MeJA), ethylene or salicylic acid (SA). {ECO:0000269\|PubMed:11950980}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source	Target Gene (A: Activate/R: Repress)
ATRM	AT2G44840(A), AT3G23240(A)

Regulation -- Hormone ? help Back to Top
Source	Hormone
AHD	ethylene

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT1G04370

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT026421	0.0	BT026421.1 Arabidopsis thaliana At1g04370 mRNA, complete cds.
GenBank	CP002684	0.0	CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
GenBank	F19P19	0.0	AC000104.1 Sequence of BAC F19P19 from Arabidopsis thaliana chromosome 1, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_171932.1	1e-94	Ethylene-responsive element binding factor 14
Swissprot	P93822	1e-95	ERF97_ARATH; Ethylene-responsive transcription factor 14
TrEMBL	C0SUS6	3e-93	C0SUS6_ARATH; Uncharacterized protein At1g04370 (Fragment)
STRING	AT1G04370.1	6e-94	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT1G04370.1
Entrez Gene	839539
iHOP	AT1G04370
wikigenes	AT1G04370

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] O Identification of Arabidopsis ethylene-responsive element binding factors with distinct induction kinetics after pathogen infection. Plant Physiol., 2002. 128(4): p. 1313-22 [PMID:11950980] Wilson IW,Kennedy GC,Peacock JW,Dennis ES Microarray analysis reveals vegetative molecular phenotypes of Arabidopsis flowering-time mutants. Plant Cell Physiol., 2005. 46(8): p. 1190-201 [PMID:15908439] McGrath KC, et al. Repressor- and activator-type ethylene response factors functioning in jasmonate signaling and disease resistance identified via a genome-wide screen of Arabidopsis transcription factor gene expression. Plant Physiol., 2005. 139(2): p. 949-59 [PMID:16183832] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Oñate-Sánchez L,Anderson JP,Young J,Singh KB AtERF14, a member of the ERF family of transcription factors, plays a nonredundant role in plant defense. Plant Physiol., 2007. 143(1): p. 400-9 [PMID:17114278] Dombrecht B, et al. MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis. Plant Cell, 2007. 19(7): p. 2225-45 [PMID:17616737] Pré M, et al. The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense. Plant Physiol., 2008. 147(3): p. 1347-57 [PMID:18467450] Camehl I,Oelm Do ethylene response factorS9 and -14 repress PR gene expression in the interaction between Piriformospora indica and Arabidopsis? Plant Signal Behav, 2010. 5(8): p. 932-6 [PMID:20505369] Anderson JP,Singh KB Interactions of Arabidopsis and M. truncatula with the same pathogens differ in dependence on ethylene and ethylene response factors. Plant Signal Behav, 2011. 6(4): p. 551-2 [PMID:21389781] Hu Y,Shen Y,Conde E Silva N,Zhou DX The role of histone methylation and H2A.Z occupancy during rapid activation of ethylene responsive genes. PLoS ONE, 2011. 6(11): p. e28224 [PMID:22140554] Moffat CS, et al. ERF5 and ERF6 play redundant roles as positive regulators of JA/Et-mediated defense against Botrytis cinerea in Arabidopsis. PLoS ONE, 2012. 7(4): p. e35995 [PMID:22563431] Jin J, et al. An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors. Mol. Biol. Evol., 2015. 32(7): p. 1767-73 [PMID:25750178] Riechmann JL,Meyerowitz EM The AP2/EREBP family of plant transcription factors. Biol. Chem., 1998. 379(6): p. 633-46 [PMID:9687012]