PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

EMT32184

Organism

Aegilops tauschii

Taxonomic ID

37682

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Aegilops

Family

NAC

Protein Properties

Length: 410aa MW: 45752.5 Da PI: 5.7644

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
EMT32184	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	89.8	4.8e-28	66	210	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkk....lelee....vikev.diykvePwdLpkkvkaeekewyfFskrdkkyatgkrknra.........tksgyW 83 lp+G++F+Pt el+ e+L+ kv + + + + +i+e+ +i++++P++Lp +k + ++++fF+k +++y g+rk+r+ + +W EMT32184 66 LPAGVKFDPTGLELL-EHLEGKVGRAPshelI---DdfipTIEEAeGICYTHPENLP-GTKMDGRNLHFFHKISNAYDVGQRKRRKisnsdhvvcDVHFRW 161 799**********.99**99965543...133334888878******.4556889*****************856666665433677 PP NAM 84 katgkdkevlskkgelvglkktLvfykgrapkge....ktdWvmheyrl 128 ++tgk+ke+l+++g +g kk+Lv+ ++++g+ kt+W+mh+y+l EMT32184 162 HKTGKSKEILDNNGVIKGWKKILVLIMRSRKDGVtsrtKTNWTMHQYHL 210 ************************655555543444*******98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.44E-30	57	229	IPR003441	NAC domain
PROSITE profile	PS51005	26.726	66	229	IPR003441	NAC domain
Pfam	PF02365	5.4E-11	67	210	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 410 aa Download sequence Send to blast
MPLLLQDEVK WHQKMITKID LSHRFISSLV TTIVAVIRNP THPPPSQIEC PNCKYHIDDL 60 SQWPGLPAGV KFDPTGLELL EHLEGKVGRA PSHELIDDFI PTIEEAEGIC YTHPENLPGT 120 KMDGRNLHFF HKISNAYDVG QRKRRKISNS DHVVCDVHFR WHKTGKSKEI LDNNGVIKGW 180 KKILVLIMRS RKDGVTSRTK TNWTMHQYHL GVDQDEKHGE LVVSKVFYQS NKDEQPVMCP 240 VNEESGPFAG EIDPTTPMTY PPQPRPPNSS PSRTKQNQEE HAALSGPDER PSRGATPDSV 300 YPEMQPYPLG LDALQGLPDP RTPPGFSHMA SWFAGTSSHS NALEDAPLSG LDERLPHGGT 360 LDAAYPDPEG QALPLDVEAL QGFPDLGTPP DIFPQDLQFG SQDIFWGEGF

Sequence ? help Back to Top

Protein Sequence Length: 410 aa Download sequence Send to blast

MPLLLQDEVK WHQKMITKID LSHRFISSLV TTIVAVIRNP THPPPSQIEC PNCKYHIDDL  60
SQWPGLPAGV KFDPTGLELL EHLEGKVGRA PSHELIDDFI PTIEEAEGIC YTHPENLPGT  120
KMDGRNLHFF HKISNAYDVG QRKRRKISNS DHVVCDVHFR WHKTGKSKEI LDNNGVIKGW  180
KKILVLIMRS RKDGVTSRTK TNWTMHQYHL GVDQDEKHGE LVVSKVFYQS NKDEQPVMCP  240
VNEESGPFAG EIDPTTPMTY PPQPRPPNSS PSRTKQNQEE HAALSGPDER PSRGATPDSV  300
YPEMQPYPLG LDALQGLPDP RTPPGFSHMA SWFAGTSSHS NALEDAPLSG LDERLPHGGT  360
LDAAYPDPEG QALPLDVEAL QGFPDLGTPP DIFPQDLQFG SQDIFWGEGF

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor regulating the transcriptional activation response to gamma irradiation (PubMed:19549833). Required for stem-cell death induced by UVB or by gamma irradiation (PubMed:20634150). Not required for ATM activation, but participates in pathways governed by both ATM and ATR sensor kinases (PubMed:19549833). Involved in DNA damage response (DDR) system that regulates cell cycle arrest (PubMed:24399300). Functional homolog of animal p53 (PubMed:24736489). Regulates SMR5 and SMR7 transcription (PubMed:24399300). Regulates DNA repair and cytokinin signaling separately and plays a key role in controlling lateral root formation under genotoxic stress. {ECO:0000269\|PubMed:19549833, ECO:0000269\|PubMed:20634150, ECO:0000269\|PubMed:24399300, ECO:0000305\|PubMed:24736489}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not induced by zeocin or ionizing radiation treatment. {ECO:0000269\|PubMed:23907539}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020187626.1	0.0	SUPPRESSOR OF GAMMA RESPONSE 1-like
Swissprot	Q6NQK2	3e-55	NAC8_ARATH; SUPPRESSOR OF GAMMA RESPONSE 1
TrEMBL	M8CCR8	0.0	M8CCR8_AEGTA; NAC domain-containing protein 8
STRING	EMT32184	0.0	(Aegilops tauschii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP2110	37	99

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G56620.1	5e-58	NAC domain containing protein 99

Publications ? help Back to Top
Yi D, et al. The Arabidopsis SIAMESE-RELATED cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species. Plant Cell, 2014. 26(1): p. 296-309 [PMID:24399300] Biever JJ,Brinkman D,Gardner G UV-B inhibition of hypocotyl growth in etiolated Arabidopsis thaliana seedlings is a consequence of cell cycle arrest initiated by photodimer accumulation. J. Exp. Bot., 2014. 65(11): p. 2949-61 [PMID:24591052] Hu Z,Cools T,Kalhorzadeh P,Heyman J,De Veylder L Deficiency of the Arabidopsis helicase RTEL1 triggers a SOG1-dependent replication checkpoint in response to DNA cross-links. Plant Cell, 2015. 27(1): p. 149-61 [PMID:25595823] Chen P,Umeda M DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana. Genes Cells, 2015. 20(8): p. 636-46 [PMID:26033196] Sjogren CA,Bolaris SC,Larsen PB Aluminum-Dependent Terminal Differentiation of the Arabidopsis Root Tip Is Mediated through an ATR-, ALT2-, and SOG1-Regulated Transcriptional Response. Plant Cell, 2015. 27(9): p. 2501-15 [PMID:26320227] Yoshiyama KO SOG1: a master regulator of the DNA damage response in plants. Genes Genet. Syst., 2016. 90(4): p. 209-16 [PMID:26617076] Weimer AK, et al. The plant-specific CDKB1-CYCB1 complex mediates homologous recombination repair in Arabidopsis. EMBO J., 2016. 35(19): p. 2068-2086 [PMID:27497297] Davis OM,Ogita N,Inagaki S,Takahashi N,Umeda M DNA damage inhibits lateral root formation by up-regulating cytokinin biosynthesis genes in Arabidopsis thaliana. Genes Cells, 2016. 21(11): p. 1195-1208 [PMID:27658920] Pedroza-García JA, et al. Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis. Plant Physiol., 2017. 173(3): p. 1735-1749 [PMID:28153919] Horvath BM, et al. Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control. EMBO J., 2017. 36(9): p. 1261-1278 [PMID:28320736] Sjogren CA,Larsen PB SUV2, which encodes an ATR-related cell cycle checkpoint and putative plant ATRIP, is required for aluminium-dependent root growth inhibition in Arabidopsis. Plant Cell Environ., 2017. 40(9): p. 1849-1860 [PMID:28556304] Yoshiyama KO,Kaminoyama K,Sakamoto T,Kimura S Increased Phosphorylation of Ser-Gln Sites on SUPPRESSOR OF GAMMA RESPONSE1 Strengthens the DNA Damage Response in Arabidopsis thaliana. Plant Cell, 2017. 29(12): p. 3255-3268 [PMID:29208704] Johnson RA, et al. SUPPRESSOR OF GAMMA RESPONSE1 Links DNA Damage Response to Organ Regeneration. Plant Physiol., 2018. 176(2): p. 1665-1675 [PMID:29222192] Ogita N, et al. Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis. Plant J., 2018. 94(3): p. 439-453 [PMID:29430765] Cao X, et al. Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots. Chemosphere, 2018. 201: p. 586-594 [PMID:29533809]