PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

EMT26799

Organism

Aegilops tauschii

Taxonomic ID

37682

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Aegilops

Family

NAC

Protein Properties

Length: 170aa MW: 19265.5 Da PI: 8.7513

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
EMT26799	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	163.7	6.6e-51	9	149	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..........kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdke 91 +ppGfrFhPt+eelv +yL++kv+++k++l ++i+evd+y++ePwdL++ + ++e+yfFs +d+ky++g+r+nrat++g+Wkatg+dk+ EMT26799 9 VPPGFRFHPTEEELVGYYLARKVSSHKIDL-DIIQEVDLYRIEPWDLQErcgkygggggGQEDPTTEYYFFSYKDRKYPSGTRTNRATAAGFWKATGRDKP 108 69**************************.99**********954676665543222234499***************************** PP NAM 92 vlsk....kgelvglkktLvfykgrapkgektdWvmheyrl 128 vls+ +++g++ktLvfy+grap+g+ktdW++heyrl EMT26799 109 VLSSssssPASVIGMRKTLVFYRGRAPNGRKTDWIIHEYRL 149 854444445**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	2.62E-51	8	156	IPR003441	NAC domain
PROSITE profile	PS51005	50.816	9	170	IPR003441	NAC domain
Pfam	PF02365	2.9E-26	10	149	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 170 aa Download sequence Send to blast
MEESSCNTVP PGFRFHPTEE ELVGYYLARK VSSHKIDLDI IQEVDLYRIE PWDLQERCGK 60 YGGGGGGQED PTTEYYFFSY KDRKYPSGTR TNRATAAGFW KATGRDKPVL SSSSSSPASV 120 IGMRKTLVFY RGRAPNGRKT DWIIHEYRLQ SNEHAPTQAC KSPSMHAWTS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	4e-46	3	149	10	140	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls (PubMed:25148240). {ECO:0000250\|UniProtKB:Q9LVA1, ECO:0000269\|PubMed:25148240}.
UniProt	Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (e.g. genes involved in secondary wall biosynthesis, cell wall modification such as xylan accumulation, and programmed cell death) (PubMed:20935069, PubMed:20488898, PubMed:22037706, PubMed:21284754). Involved in xylem formation in roots and shoots, especially regulating protoxylem vessel differentiation by promoting immature xylem vessel-specific genes expression (PubMed:16103214, PubMed:18445131, PubMed:20488898, PubMed:21498679, PubMed:21284754). Can activate the expression of several genes including XCP1, MYB46, NAC010/SND3, MYB103, MYB58, MYB63, MYB83, KNAT7, ASL19 and ASL20 (PubMed:17890373, PubMed:19088331, PubMed:18952777, PubMed:19122102, PubMed:19808805, PubMed:20935069, PubMed:21284754). {ECO:0000269\|PubMed:16103214, ECO:0000269\|PubMed:17890373, ECO:0000269\|PubMed:18445131, ECO:0000269\|PubMed:18952777, ECO:0000269\|PubMed:19088331, ECO:0000269\|PubMed:19122102, ECO:0000269\|PubMed:19808805, ECO:0000269\|PubMed:20488898, ECO:0000269\|PubMed:20935069, ECO:0000269\|PubMed:21284754, ECO:0000269\|PubMed:21498679, ECO:0000269\|PubMed:22037706}.; FUNCTION: Required for the soilborne fungal pathogen Verticillium longisporum-induced transdifferentiation of chloroplast-containing bundle sheath cells to functional xylem elements leading to stunted growth, vein clearing, and leaf chloroses, as well as xylem hyperplasia within the vasculature of leaves, hypocotyls, and roots due to reinitiation of cambial activity and transdifferentiation of xylem parenchyma cells. This developmental reprogramming mediates also an increased drought stress tolerance. {ECO:0000269\|PubMed:23023171}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By brassinosteroids (e.g. brassinolide BL), auxin (e.g. 2,4-dichlorphenoxyacetic acid 2,4-D) and cytokinin (e.g. kinetin), with a synergistic effect (PubMed:16103214, PubMed:22345435). Up-regulated in a feed-back loop by ASL20 (PubMed:19088331). Levels are monitored by proteasome-mediated degradation (PubMed:18445131). Repressed by WEE1 upon replication stress to prevent premature tracheary element differentiation (PubMed:21498679). Accumulates during infection by the soilborne fungal pathogen Verticillium longisporum, especially in tissues undergoing de novo xylem formation (PubMed:23023171). {ECO:0000269\|PubMed:16103214, ECO:0000269\|PubMed:18445131, ECO:0000269\|PubMed:19088331, ECO:0000269\|PubMed:21498679, ECO:0000269\|PubMed:22345435, ECO:0000269\|PubMed:23023171}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020178030.1	1e-115	NAC domain-containing protein 30-like
Swissprot	O65508	8e-70	NAC76_ARATH; NAC domain-containing protein 76
Swissprot	Q9C8W9	6e-70	NAC30_ARATH; NAC domain-containing protein 30
TrEMBL	M8BXW0	1e-125	M8BXW0_AEGTA; NAC domain-containing protein 7
STRING	EMT26799	1e-126	(Aegilops tauschii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP2594	37	91

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36160.1	3e-71	NAC domain containing protein 76

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kakehi J, et al. Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana. PLoS ONE, 2015. 10(1): p. e0117309 [PMID:25625317] Li Z, et al. A Transcriptional and Metabolic Framework for Secondary Wall Formation in Arabidopsis. Plant Physiol., 2016. 172(2): p. 1334-1351 [PMID:27566165] de Lucas M, et al. Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation. Plant Cell, 2016. 28(10): p. 2616-2631 [PMID:27650334] Tan TT, et al. Transcription Factors VND1-VND3 Contribute to Cotyledon Xylem Vessel Formation. Plant Physiol., 2018. 176(1): p. 773-789 [PMID:29133368] Ohashi-Ito K,Iwamoto K,Fukuda H LOB DOMAIN-CONTAINING PROTEIN 15 Positively Regulates Expression of VND7, a Master Regulator of Tracheary Elements. Plant Cell Physiol., 2018. 59(5): p. 989-996 [PMID:29444288]