PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 912555
Common NameARALYDRAFT_912555
Organism
Arabidopsis lyrata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family AP2
Protein Properties Length: 552aa    MW: 61236.4 Da    PI: 7.4661
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
912555genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP249.79.3e-16278337155
     AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
             s+y+GV++++++gr++A+++d   +  g  ++ ++++lg ++ +e+Aa+a++ a++k++g
  912555 278 SQYRGVTRHRWTGRYEAHLWDnSFKkEGhsRKgRQVYLGGYDMEEKAARAYDLAALKYWG 337
             78*******************644456687446*************************98 PP
2AP2513.5e-16380431155
     AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
             s y+GV+++++ grW A+I  +     +k  +lg+fgt eeAa+a++ a+ k++g
  912555 380 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFGTQEEAAEAYDVAAIKFRG 431
             57****************988532...5************************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000182.27E-21278344No hitNo description
PfamPF008476.4E-13278337IPR001471AP2/ERF domain
SuperFamilySSF541712.29E-16278346IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.102.2E-15279345IPR001471AP2/ERF domain
PROSITE profilePS5103218.755279345IPR001471AP2/ERF domain
SMARTSM003801.5E-26279351IPR001471AP2/ERF domain
PRINTSPR003671.2E-6280291IPR001471AP2/ERF domain
PfamPF008471.7E-11380431IPR001471AP2/ERF domain
CDDcd000187.12E-26380441No hitNo description
SuperFamilySSF541716.54E-18380440IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.102.2E-18381439IPR001471AP2/ERF domain
PROSITE profilePS5103218.966381439IPR001471AP2/ERF domain
SMARTSM003803.8E-34381445IPR001471AP2/ERF domain
PRINTSPR003671.2E-6421441IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007276Biological Processgamete generation
GO:0010492Biological Processmaintenance of shoot apical meristem identity
GO:0042127Biological Processregulation of cell proliferation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 552 aa     Download sequence    Send to blast
MKSFCDNDDN NHSNTTNLLG FSLSSNMMKM GGRGGGEAIY SSTTSSAATS SSSVPPQLVV  60
GDSTSNFGVC YGSNSAGEIY SHMSVMPLRS DGSLCLMEAL NRSSHSNHHQ DSSPKMEDFF  120
GTHHNNTSHK EAMDLSLDSL FYNTTHEPNT TTNFQEFFSF PQTRNHHQEE TRNYENDPGL  180
TNGGSFNVGV YGEFQQSLSL SMSPGSQSSC ITGSHHHQQN QNQNHHQISE ALVETSVGFE  240
TTTMAAAKKK RGQEDVVVVG QKQIVHRKSI DTFGQRTSQY RGVTRHRWTG RYEAHLWDNS  300
FKKEGHSRKG RQVYLGGYDM EEKAARAYDL AALKYWGPST HTNFSAENYQ KEIEDMKNMS  360
RQEYVAHLRR KSSGFSRGAS IYRGVTRHHQ HGRWQARIGR VAGNKDLYLG TFGTQEEAAE  420
AYDVAAIKFR GTNAVTNFDI TRYDVDRIMS SNTLLSGELA RRNNNSIVVR NNEDQTALNA  480
VVDGGSNKEV STPERLLSFP AIFALPQVNQ KMFGSNVVGN MSSWTSNPNA ELKTVALTMP  540
QMPVFAAWAD S*
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00088SELEXTransfer from AT4G37750Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMap912555
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankATU402560.0U40256.1 Arabidopsis thaliana ovule development protein (AINTEGUMENTA) mRNA, complete cds.
GenBankATU413390.0U41339.1 Arabidopsis thaliana ANT (AINTEGUMENTA) mRNA, complete cds.
GenBankAY0807060.0AY080706.1 Arabidopsis thaliana putative ovule development protein aintegumenta (At4g37750) mRNA, complete cds.
GenBankAY1172070.0AY117207.1 Arabidopsis thaliana putative ovule development protein aintegumenta (At4g37750) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002868967.10.0AP2-like ethylene-responsive transcription factor ANT
SwissprotQ389140.0ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLD7MA080.0D7MA08_ARALL; Uncharacterized protein
STRINGscaffold_700297.10.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM31372863
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.10.0AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]