PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 879559
Common NameARALYDRAFT_679003
Organism
Arabidopsis lyrata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 451aa    MW: 49703.8 Da    PI: 5.8681
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
879559genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH352.5e-11270312754
             HHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS
     HLH   7 erErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 
             ++ErrRR+++N+++  Lr+++Pk +      K++ a+iL  A++Y+k+L
  879559 270 MAERRRRKKLNDRLYMLRSVVPKiS------KMDRAAILGDAIDYLKEL 312
             79*********************66......****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.555263312IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.16E-16266337IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003538.3E-14269318IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000105.9E-9269312IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.2E-15270327IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.71E-12270316No hitNo description
PROSITE profilePS516718.734378450IPR002912ACT domain
CDDcd048738.58E-7379420No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008152Biological Processmetabolic process
GO:0010444Biological Processguard mother cell differentiation
GO:0050826Biological Processresponse to freezing
GO:0016597Molecular Functionamino acid binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 451 aa     Download sequence    Send to blast
MNGDGVWLDG AGESPEVNNN EAASWVRNPD EDWFNNPPPP PQILHSNQND FRFNGGFPLN  60
PSENLLLLLQ QSIDSSCSAP LHPFTLDAAS QQQQQQQEQS FLATKACIAS LLNVPTSNIN  120
TFDEFGFDSG FLSQQFHGNQ SPNSMNFAGL NHQGPDFLTS RSLPAPENSS GSCGLSPLFE  180
NRAKVLKPLE VLASSGSQPT LFQKRAAMRQ SSSSKMCNSE SSSEMRKSSY EREIDDTSTG  240
IIDISGLNYE SDEHINNKGK KKGMPAKNLM AERRRRKKLN DRLYMLRSVV PKISKMDRAA  300
ILGDAIDYLK ELLQRINDLH TELESTPPSS SSLHPLTPTP QTLSYRVKEE LCPSSSLPSP  360
KGQQPRVEVR LREGKAVNIH MFCGRRPGLL LSTMRALDNL GLDVQQAVIS CFNGFALDVF  420
RAEQCQEDHD VLPEQIKAVL LDTAGYAGLV *
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1259277KKKGMPAKNLMAERRRRKK
2271278ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtMediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269|PubMed:18641265, ECO:0000269|PubMed:28507175}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap879559
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1180110.0AK118011.1 Arabidopsis thaliana At1g12860 mRNA for putative bHLH transcription factor (bHLH033), complete cds, clone: RAFL19-21-N13.
GenBankBT0053770.0BT005377.1 Arabidopsis thaliana At1g12860 mRNA, complete cds.
GenBankEU3696700.0EU369670.1 Arabidopsis thaliana bHLH protein (SCREAM2) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002889974.10.0transcription factor SCREAM2
SwissprotQ9LPW30.0SCRM2_ARATH; Transcription factor SCREAM2
TrEMBLD7KPD70.0D7KPD7_ARALL; Predicted protein
STRINGAl_scaffold_0001_13260.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM19522782
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G12860.10.0bHLH family protein
Publications ? help Back to Top
  1. Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV
    The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity.
    Dokl. Biol. Sci., 2009.
    [PMID:19760875]
  2. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Emmerstorfer A, et al.
    Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris.
    Biotechnol J, 2015. 10(4): p. 623-35
    [PMID:25641738]
  5. Lee HG,Seo PJ
    The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis.
    Plant J., 2015. 82(6): p. 962-77
    [PMID:25912720]
  6. Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC
    Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31
    [PMID:27382177]
  7. Fu ZW,Wang YL,Lu YT,Yuan TT
    Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis.
    Plant Sci., 2016. 252: p. 282-289
    [PMID:27717464]
  8. de Marcos A, et al.
    A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development.
    Plant Physiol., 2017. 174(2): p. 823-842
    [PMID:28507175]