PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

495549

Common Name

ARALYDRAFT_495549

Organism

Arabidopsis lyrata

Taxonomic ID

81972

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 235aa MW: 25487.9 Da PI: 8.8356

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
495549	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36.8	7.3e-12	75	122	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rE++RRdr+N++f eL +l + + +K +Ka+iL Av+ + +L 495549 75 SKACREKQRRDRLNDKFMELGAILEPG---NPPKTDKAAILVDAVRMVTQL 122 5678********************8...78************99988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	9.95E-14	62	137	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	4.02E-10	69	127	No hit	No description
PROSITE profile	PS50888	13.497	71	122	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.7E-13	74	144	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.6E-9	75	122	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.3E-9	77	128	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd14686	0.00513	137	169	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 235 aa Download sequence Send to blast
MVSPENANWI CDLIDADYGS FTIQGPGFSW PVQQPIGVSS NSSAGVDGSA GNSEASKEPG 60 SKKRGRCESS SATSSKACRE KQRRDRLNDK FMELGAILEP GNPPKTDKAA ILVDAVRMVT 120 QLRGEAQKLK DSNSSLQDKI KELKTEKNEL RDEKQRLKTE KEKLEQQLKA MNAPQPSFFP 180 APPMMPTAFA SAQGQAPGNK MVPIISYPGV AMWQFMPPAS VDTSQDHVLR PPVA*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	495549

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF488629	0.0	AF488629.1 Arabidopsis thaliana clone bHLH105 putative bHLH transcription factor mRNA, complete cds.
GenBank	AY054585	0.0	AY054585.1 Arabidopsis thaliana Unknown protein (At5g54680; K5F14.2) mRNA, complete cds.
GenBank	BT002189	0.0	BT002189.1 Arabidopsis thaliana Unknown protein (At5g54680) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_200279.1	1e-173	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Refseq	XP_020888968.1	1e-173	transcription factor ILR3
Swissprot	Q9FH37	1e-174	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A0A178UAU8	1e-171	A0A178UAU8_ARATH; ILR3
TrEMBL	D7MUC3	1e-171	D7MUC3_ARALL; Uncharacterized protein
STRING	AT5G54680.1	1e-172	(Arabidopsis thaliana)
STRING	fgenesh2_kg.8__1365__AT5G54680.1	1e-172	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1437	28	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	1e-142	bHLH family protein

Link Out ? help Back to Top
Phytozome	495549
Entrez Gene	9300427

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]