PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 489687
Common NameARALYDRAFT_489687
Organism
Arabidopsis lyrata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C2H2
Protein Properties Length: 388aa    MW: 44731.3 Da    PI: 6.6156
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
489687genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H210.70.001681103323
              ET..TTTEEESSHHHHHHHHHHT CS
  zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
              C+   Cgk+F + s L++H   H
   489687  81 CSydGCGKTFFDVSALRKHSHIH 103
              78889**************7766 PP
2zf-C2H216.32.7e-05108132123
              EEET..TTTEEESSHHHHHHHHHHT CS
  zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
              y+C    Cgk F ++s LkrH   H
   489687 108 YVCDqeGCGKKFLDSSKLKRHHLIH 132
              99*******************9988 PP
3zf-C2H221.18.4e-07138162123
              EEET..TTTEEESSHHHHHHHHHHT CS
  zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
              y+C+   Cgk Fs   nL++H++tH
   489687 138 YVCTyeGCGKAFSLDFNLRSHMKTH 162
              99**********************9 PP
4zf-C2H213.40.00022168193123
              EEET..TTTEEESSHHHHHHHHHH.T CS
  zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
              + Cp   Cgk++ + + Lk+H    H
   489687 168 HICPysGCGKRYAHEYKLKNHVAAyH 193
              68*******************87666 PP
5zf-C2H212.90.00033230255123
              EEET..TTTEEESSHHHHHHHHHH.T CS
  zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
              y Cp   C k + + + Lk H+++ H
   489687 230 YACPyeGCEKAYIHEYKLKLHLKReH 255
              89*********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.603.7E-1474104IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.94979108IPR007087Zinc finger, C2H2
SMARTSM003550.005379103IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028081103IPR007087Zinc finger, C2H2
SuperFamilySSF576675.73E-982132No hitNo description
Gene3DG3DSA:3.30.160.603.1E-13105127IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.173108137IPR007087Zinc finger, C2H2
SMARTSM003550.0037108132IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280110132IPR007087Zinc finger, C2H2
SuperFamilySSF576672.17E-14119173No hitNo description
Gene3DG3DSA:3.30.160.602.8E-19128164IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.944138167IPR007087Zinc finger, C2H2
SMARTSM003554.0E-4138162IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280140162IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.605.1E-7165189IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0074168193IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280170193IPR007087Zinc finger, C2H2
SuperFamilySSF576671.21E-5225253No hitNo description
Gene3DG3DSA:3.30.160.606.7E-9226252IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.533230260IPR007087Zinc finger, C2H2
SMARTSM003550.012230255IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280232255IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 388 aa     Download sequence    Send to blast
MDHHNYQYQN PFERRPILKS KAPAVKWIKE WVPQDIVATG GKCYLHKWVT EDTFNRHKEK  60
EKEPDVPEPE PEPTTEILFL CSYDGCGKTF FDVSALRKHS HIHGERQYVC DQEGCGKKFL  120
DSSKLKRHHL IHTGVRNYVC TYEGCGKAFS LDFNLRSHMK THSQENYHIC PYSGCGKRYA  180
HEYKLKNHVA AYHEKNGAGE TPKYTPPAEK VSRTVKTPAA VYGPSSDRPY ACPYEGCEKA  240
YIHEYKLKLH LKREHPGHLP EENADTLTLN KHNGSDRNDM DDGSDQDVYR KHTSNGKSQT  300
HKQQTRAKPN MRTPPAKAGK KGSTSSPAKV RIAKKPWQAK ETFEEVEREE EEDSEETEED  360
RDNVDDGWRF GENNEEDDDD EETEYED*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C3e-36811928117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap489687
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0731620.0AB073162.1 Arabidopsis thaliana DNA, chromosome 4 centromere region, BAC clone:F8H12.
GenBankCP0026870.0CP002687.1 Arabidopsis thaliana chromosome 4 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020878944.10.0uncharacterized zinc finger protein At4g06634 isoform X1
SwissprotQ2V3L30.0YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLD7M7L70.0D7M7L7_ARALL; Zinc finger family protein
STRINGfgenesh2_kg.6__2821__AT4G06634.10.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM58592846
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.10.0C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]