PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

486140

Common Name

ARALYDRAFT_486140, ORG3

Organism

Arabidopsis lyrata

Taxonomic ID

81972

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 254aa MW: 28607.3 Da PI: 6.2493

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
486140	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	51.4	2e-16	73	125	1	55
CHHHHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS HLH 1 rrrahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 ++ +hn+ Er RR++iNs f+ Lr++lP + +skKls e++ k +YI +Lq 486140 73 KKLNHNASERDRRKKINSLFSSLRSCLPVsD---QSKKLSIPETVSKSLKYIPELQ 125 6789***********************66...*****************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	14.964	72	124	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.2E-15	73	138	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.69E-15	73	129	No hit	No description
Pfam	PF00010	1.2E-13	73	125	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	2.09E-17	73	142	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.1E-12	78	130	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010106	Biological Process	cellular response to iron ion starvation
GO:0055072	Biological Process	iron ion homeostasis
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 254 aa Download sequence Send to blast
MCALVPPLFP NFGWPLTGQC ESYYGGGDNL NNGTFLDFPV PPTYGVLTHH QNSLEVSVSS 60 EGNEIANNPV VAKKLNHNAS ERDRRKKINS LFSSLRSCLP VSDQSKKLSI PETVSKSLKY 120 IPELQQQVKK LLQKKEELLV RVSGHRDFEI YDKQQSKAVA SYLSTVSATR LGDNEVMVQI 180 SSSKIHNFSI SNVLGGIEED GVVLVDVSSS RSQGERLFYT LHLQVENMDD YYKINCEELS 240 ERMLYLYEKC ENSF

Cis-element ? help Back to Top
Source	Link
PlantRegMap	486140

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by OBP3, auxin and salicylic acid (SA). Repressed by jasmonic acid (JA), UV LIGHT, and heat treatments. Up regulated by iron deficiency in roots and leaves, as well as by nickel, high zinc or high copper treatments. Repressed by high iron, low copper and low zinc treatments. {ECO:0000269\|PubMed:12679534, ECO:0000269\|PubMed:12887587, ECO:0000269\|PubMed:17516080}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF488576	0.0	AF488576.1 Arabidopsis thaliana clone bHLH038 putative bHLH transcription factor mRNA, complete cds.
GenBank	AK221542	0.0	AK221542.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor, complete cds, clone: RAFL07-73-C01.
GenBank	BT026419	0.0	BT026419.1 Arabidopsis thaliana At3g56970 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020881758.1	0.0	transcription factor ORG2
Swissprot	Q9M1K1	1e-164	ORG2_ARATH; Transcription factor ORG2
TrEMBL	D7LVM0	0.0	D7LVM0_ARALL; OBP3-responsive gene 3 (Fragment)
STRING	fgenesh2_kg.5__2132__AT3G56970.1	0.0	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM482	28	153

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G56970.1	1e-152	bHLH family protein

Link Out ? help Back to Top
Phytozome	486140
Entrez Gene	9312459

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Matsuoka K, et al. Gibberellin-induced expression of Fe uptake-related genes in Arabidopsis. Plant Cell Physiol., 2014. 55(1): p. 87-98 [PMID:24192296] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Shen C, et al. Involvement of endogenous salicylic acid in iron-deficiency responses in Arabidopsis. J. Exp. Bot., 2016. 67(14): p. 4179-93 [PMID:27208542] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Kailasam S,Wang Y,Lo JC,Chang HF,Yeh KC S-Nitrosoglutathione works downstream of nitric oxide to mediate iron-deficiency signaling in Arabidopsis. Plant J., 2018. 94(1): p. 157-168 [PMID:29396986] Kurt F,Filiz E Genome-wide and comparative analysis of bHLH38, bHLH39, bHLH100 and bHLH101 genes in Arabidopsis, tomato, rice, soybean and maize: insights into iron (Fe) homeostasis. Biometals, 2018. 31(4): p. 489-504 [PMID:29546482]