PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 473593
Common NameARALYDRAFT_473593
Organism
Arabidopsis lyrata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C2H2
Protein Properties Length: 506aa    MW: 55782.4 Da    PI: 6.0318
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
473593genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H221.18.4e-07251272223
              EETTTTEEESSHHHHHHHHHHT CS
  zf-C2H2   2 kCpdCgksFsrksnLkrHirtH 23 
               C++Cgk F+r  nL+ H+r H
   473593 251 FCTICGKGFKRDANLRMHMRGH 272
              6*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.14E-5248276No hitNo description
PROSITE profilePS5015712.03250277IPR007087Zinc finger, C2H2
SMARTSM003550.0026250272IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.607.7E-6251303IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280252272IPR007087Zinc finger, C2H2
SMARTSM0035567301334IPR015880Zinc finger, C2H2-like
SMARTSM0035545339361IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010044Biological Processresponse to aluminum ion
GO:0010447Biological Processresponse to acidic pH
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 506 aa     Download sequence    Send to blast
METEDDLCNN NWGSSSSKSR EPGLSDGGNQ TFAGFASQQK WEDASILDYE MGVEPSLQVF  60
DEMKASGQAN VDFLQGVRAQ AWDPRTMLSN LSFMEQKIHQ LQDLVHLLVG RGGQLQGRQD  120
ELAAQQQQLI TTDLTSIIIQ LISTAGSLLP SVKHNMSTAP GPYTGQPGSA LFPYAREANN  180
VASQSQNNNN CGAQEFDLPK PVVVDERESH VVEEHEMKDE DDAEEGENLL PGSYEILQLE  240
KEEILAPHTH FCTICGKGFK RDANLRMHMR GHGDEYKTAA ALAKPNKESV PGSEPMLIKR  300
YSCPFLGCKR NKEHKKFQPL KTILCVKNHY KRTHCDKSFT CSRCHTKKFS VIADLKTHEK  360
HCGKNKWLCS CGTTFSRKDK LFGHIALFQG HTPAIPLEET KPSASTSTQR GSSDGGNNNQ  420
GMVGFNLGSA SNANQETAQP GMMDGKISFD ESFSPMNFDT CNFGGFHEFP RLMFDDSESS  480
FQMLIANACG FSPRNVGESV SDTSL*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269|PubMed:17535918, ECO:0000269|PubMed:18826429, ECO:0000269|PubMed:19321711, ECO:0000269|PubMed:23935008}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00196ampDAPTransfer from AT1G34370Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMap473593
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269|PubMed:17535918}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB3002360.0AB300236.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Ler.
GenBankAB3002380.0AB300238.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Kl-5.
GenBankAB3002390.0AB300239.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Col-4.
GenBankAB3002400.0AB300240.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Tu-0.
GenBankAB3002410.0AB300241.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Lo-1.
GenBankAB3002420.0AB300242.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Kb-0.
GenBankAB3002430.0AB300243.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Pi-0.
GenBankAB3002440.0AB300244.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Fr-3.
GenBankAB3002450.0AB300245.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Go-0.
GenBankAB3002460.0AB300246.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Van-3.
GenBankAB3002470.0AB300247.1 Arabidopsis thaliana STOP1 gene for C2-H2 zinc finger protein, complete cds, ecotype: Li-1.
GenBankAC0239130.0AC023913.7 Arabidopsis thaliana chromosome 1 BAC F7P12 genomic sequence, complete sequence.
GenBankAK2271280.0AK227128.1 Arabidopsis thaliana mRNA for putative zinc finger protein, complete cds, clone: RAFL09-80-D13.
GenBankCP0026840.0CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020867314.10.0protein SENSITIVE TO PROTON RHIZOTOXICITY 1 isoform X1
SwissprotQ9C8N50.0STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBLD7KK610.0D7KK61_ARALL; Zinc finger family protein
STRINGfgenesh2_kg.1__3547__AT1G34370.20.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM69772644
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G34370.20.0C2H2 family protein
Publications ? help Back to Top
  1. Kobayashi Y, et al.
    Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions.
    Plant Physiol., 2013. 163(1): p. 180-92
    [PMID:23839867]
  2. Yokosho K,Yamaji N,Ma JF
    Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench).
    Plant Cell Physiol., 2014. 55(12): p. 2077-91
    [PMID:25273892]
  3. Geng X, et al.
    LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis.
    Plant J., 2017. 90(3): p. 491-504
    [PMID:28181322]
  4. Balzergue C, et al.
    Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation.
    Nat Commun, 2017. 8: p. 15300
    [PMID:28504266]
  5. Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A
    Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation.
    Front Plant Sci, 2017. 8: p. 822
    [PMID:28567051]
  6. Jiang F, et al.
    Identification and characterization of suppressor mutants of stop1.
    BMC Plant Biol., 2017. 17(1): p. 128
    [PMID:28738784]
  7. Daspute AA, et al.
    Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
    Front Plant Sci, 2017. 8: p. 1358
    [PMID:28848571]
  8. Sharma A,Wai CM,Ming R,Yu Q
    Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis.
    Genome Biol Evol, 2017. 9(9): p. 2170-2190
    [PMID:28922793]
  9. Zhang Y, et al.
    The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 118
    [PMID:29491872]