PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_9922_f_2

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

HB-other

Protein Properties

Length: 253aa MW: 28694.2 Da PI: 10.4525

Description

HB-other family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_9922_f_2	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	28.9	2e-09	184	232	6	54
S--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHH CS Homeobox 6 tftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRak 54 +++k q+++Le ++++++ ps +++ + + ++L+ r++ WF +Ra Neem_9922_f_2 184 RLKKVQVKTLEMVYRRSKRPSNAMISSIVQVTNLPRRRIVKWFEDKRAE 232 57889******************************************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	9.863	176	236	IPR001356	Homeobox domain
SuperFamily	SSF46689	5.13E-10	179	245	IPR009057	Homeodomain-like
CDD	cd00086	1.56E-7	179	231	No hit	No description
SMART	SM00389	4.2E-6	182	240	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	1.9E-9	184	243	IPR009057	Homeodomain-like
Pfam	PF00046	6.0E-7	184	232	IPR001356	Homeobox domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0002229	Biological Process	defense response to oomycetes
GO:0009414	Biological Process	response to water deprivation
GO:0009682	Biological Process	induced systemic resistance
GO:0009787	Biological Process	regulation of abscisic acid-activated signaling pathway
GO:0010118	Biological Process	stomatal movement
GO:0050832	Biological Process	defense response to fungus
GO:2000022	Biological Process	regulation of jasmonic acid mediated signaling pathway
GO:2000071	Biological Process	regulation of defense response by callose deposition
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 253 aa Download sequence Send to blast
MALALSMSIT SSSRAVHCLS PSHNERLFAG HLKTLNLVLP RHPLSPFALA FSRRRNNGPA 60 ITSSSSSSKK KKGFPLCKKL DAMPENSCLK RSCNNCEQKH KIKSIAAELC LDRSVVLEML 120 REPPPNLLML SAALPDEPAA KVLVHEVKHT ETIMAETTVH AVEPETKEEE PVHDRQHRWS 180 AQKRLKKVQV KTLEMVYRRS KRPSNAMISS IVQVTNLPRR RIVKWFEDKR AEEGVPEQRT 240 PYQWPDPETV SSR

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	52	71	RRRNNGPAITSSSSSSKKKK

Functional Description ? help Back to Top
Source	Description
UniProt	May modulate chromatin structure by regulation of nucleosome assembly/disassembly (By similarity). Homeodomain transcription factor that mediates jasmonic acid (JA)-mediated COI1-dependent and abscisic acid (ABA)-mediated PMR4-dependent resistance to infection by necrotrophic fungal pathogens (e.g. B.cinerea and P.cucumerina) and bacterial pathogens (e.g. P.syringae DC3000); this resistance involves at least callose deposition (PubMed:15923348, PubMed:20836879, PubMed:21564353). Required for the P.fluorescens WCS417r-triggered JA-dependent induced systemic resistance (ISR) against both P.syringae DC3000 and H.arabidopsidis (PubMed:20836879). Negative regulator of the ABA-dependent drought resistance (PubMed:19175769). {ECO:0000250\|UniProtKB:Q70Z19, ECO:0000269\|PubMed:15923348, ECO:0000269\|PubMed:19175769, ECO:0000269\|PubMed:20836879, ECO:0000269\|PubMed:21564353}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Constitutively expressed in healthy plants but repressed in response to infection by necrotrophic fungi (PubMed:15923348). Repressed by drought and abscisic acid (ABA) (PubMed:19175769). {ECO:0000269\|PubMed:15923348, ECO:0000269\|PubMed:19175769}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006450473.1	7e-84	protein OVEREXPRESSOR OF CATIONIC PEROXIDASE 3 isoform X3
Swissprot	Q8H0V5	1e-52	OCP3_ARATH; Protein OVEREXPRESSOR OF CATIONIC PEROXIDASE 3
TrEMBL	V4TT40	2e-82	V4TT40_9ROSI; Uncharacterized protein
STRING	XP_006450473.1	3e-83	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM12077	26	31

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G11270.1	7e-55	overexpressor of cationic peroxidase 3

Publications ? help Back to Top
García-Andrade J,Ramírez V,López A,Vera P Mediated plastid RNA editing in plant immunity. PLoS Pathog., 2013. 9(10): p. e1003713 [PMID:24204264] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Gamir J,Pastor V,Kaever A,Cerezo M,Flors V Targeting novel chemical and constitutive primed metabolites against Plectosphaerella cucumerina. Plant J., 2014. 78(2): p. 227-40 [PMID:24506441]