PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_9116_f_3

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

Dof

Protein Properties

Length: 309aa MW: 33967 Da PI: 6.9616

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_9116_f_3	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	128.3	2.2e-40	51	111	2	62
zf-Dof 2 kekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 +++alkcprCdst+tkfCyynnyslsqPryfCk+CrryWtkGG+lrn+PvGgg+rknkk+s Neem_9116_f_3 51 HDQALKCPRCDSTHTKFCYYNNYSLSQPRYFCKTCRRYWTKGGTLRNIPVGGGCRKNKKVS 111 7899******************************************************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD007478	5.0E-28	45	105	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	9.7E-34	52	109	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	29.189	55	109	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	57	93	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010067	Biological Process	procambium histogenesis
GO:0010087	Biological Process	phloem or xylem histogenesis
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 309 aa Download sequence Send to blast
MGLTSLQVCM DSSDWLQGSI HEESGLDSSS PSGDLLTCSR PLMERRLRPQ HDQALKCPRC 60 DSTHTKFCYY NNYSLSQPRY FCKTCRRYWT KGGTLRNIPV GGGCRKNKKV SSKKSNDQSI 120 NQNPASSSHN PTDLQLSFPE MQFSHLGNIL GTHGTLANPN FMDTKYNAML ENSRPIDFME 180 SKLEAIVGSS RNYDFMGNNE LGMVGGLGNL GHHGLTPNVH NLCSPFGMSL EGNGGTFIDT 240 CQRLMLPYDA NEDQNAIDVK PNTKMLSLDW QDQGCSDVGK DAFGYLGNLG PSWSGMMNGY 300 GSSAANSLV

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Promotes expression (PubMed:19915089). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). Involved in the regulation of interfascicular cambium formation and vascular tissue development, particularly at a very early stage during inflorescence stem development; promotes both cambium activity and phloem specification, but prevents xylem specification (PubMed:19915089). {ECO:0000250\|UniProtKB:Q9M2U1, ECO:0000269\|PubMed:19915089, ECO:0000269\|PubMed:30626969}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00580	DAP	Transfer from AT5G62940	Download

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006439825.1	0.0	dof zinc finger protein DOF5.6
Refseq	XP_024954523.1	0.0	dof zinc finger protein DOF5.6
Swissprot	Q9FM03	4e-62	DOF56_ARATH; Dof zinc finger protein DOF5.6
TrEMBL	A0A061FV52	0.0	A0A061FV52_THECC; Dof-type zinc finger DNA-binding family protein isoform 1
TrEMBL	A0A067FQG5	0.0	A0A067FQG5_CITSI; Uncharacterized protein
TrEMBL	A0A2H5P4T4	0.0	A0A2H5P4T4_CITUN; Uncharacterized protein
TrEMBL	V4TN03	0.0	V4TN03_9ROSI; Uncharacterized protein
STRING	XP_006476784.1	0.0	(Citrus sinensis)
STRING	EOY20732	0.0	(Theobroma cacao)
STRING	XP_006439825.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6374	27	46

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G62940.1	3e-50	Dof family protein

Publications ? help Back to Top
Miyashima S, et al. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature, 2019. 565(7740): p. 490-494 [PMID:30626969]