PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_6837_f_2
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family HSF
Protein Properties Length: 273aa    MW: 30503.1 Da    PI: 7.461
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_6837_f_2genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind120.59.6e-38101012102
                    HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXX CS
   HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkelleki 97 
                    Fl+k+y++++d++++++isw+e+g++fvv+++ +fak++Lp+yFkh+nf+SFvRQLn+YgF+k+  ++         weF++++F++g+kell++i
  Neem_6837_f_2  10 FLMKTYQLVDDPNTDDVISWNESGTTFVVWKTADFAKDLLPNYFKHNNFSSFVRQLNTYGFRKIVADK---------WEFANENFRRGQKELLTEI 96 
                    9****************************************************************999.........******************* PP

                    XXXXX CS
   HSF_DNA-bind  98 krkks 102
                    +r+k+
  Neem_6837_f_2  97 QRRKT 101
                    ***96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004158.6E-60699IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene3DG3DSA:1.10.10.105.4E-39799IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467858.16E-35799IPR011991Winged helix-turn-helix DNA-binding domain
PRINTSPR000565.1E-211033IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004477.4E-331099IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000565.1E-214860IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043404973IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000565.1E-216173IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009408Biological Processresponse to heat
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 273 aa     Download sequence    Send to blast
MTQRTVPAPF LMKTYQLVDD PNTDDVISWN ESGTTFVVWK TADFAKDLLP NYFKHNNFSS  60
FVRQLNTYGF RKIVADKWEF ANENFRRGQK ELLTEIQRRK TVTPSATPAT AKAKATSPSN  120
SGEDMGSTST SSPDSKNQGS VETTKFADLS DENAKLKRDN EMLSSELAQA KKQCDELIAF  180
LTDYVKVGPE QINRIMRQRS CGSSCDGLVG DDHGHENEKE GSDGGELKLF GVWLKGEQKK  240
RAREESVACG GSHHELKNVE FRGPLMKSSK VCN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B3e-27610126131Heat shock factor protein 1
5d5v_B3e-27610126131Heat shock factor protein 1
5d5v_D3e-27610126131Heat shock factor protein 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006466606.11e-164heat shock factor protein HSF24
SwissprotP223351e-118HSF24_SOLPE; Heat shock factor protein HSF24
TrEMBLA0A2H5PJX41e-162A0A2H5PJX4_CITUN; Uncharacterized protein
STRINGXP_006466606.11e-163(Citrus sinensis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM61012546
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G36990.13e-95heat shock factor 4
Publications ? help Back to Top
  1. Scharf KD, et al.
    Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF.
    EMBO J., 1990. 9(13): p. 4495-501
    [PMID:2148291]