PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_6786_f_2
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family TCP
Protein Properties Length: 391aa    MW: 42272.6 Da    PI: 7.9409
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_6786_f_2genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP133.71.7e-41732252115
            TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssasec.eaesssssasnsssg........ 88 
                    ++k+++++++hTkv+gR+RR+R++a+caar+F+L++eLG+++d++tieWLlqqa+pa++++tgt++++a+++  + s +ss+s+ s +        
  Neem_6786_f_2  73 PPKRTSTKDRHTKVDGRGRRIRMPALCAARVFQLTRELGHKSDGETIEWLLQQAEPAVIAATGTGTIPANFTsLNISLRSSGSSMSVPsqlrsvny 168
                    789*************************************************************99999888877777777775555555556666 PP

            TCP  89 .............................kaaksaa.kskksqksaasalnlakesr 115
                                                 +++ +a+ + k++ +++++ l+l++e+ 
  Neem_6786_f_2 169 nsnfsmqqrrslfpgigldnatptflnfqSSNLNAMlQAKQEYRDNNNSLELSAETE 225
                    666777777778888877777777776653333333344444455555555555444 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036341.8E-4377244IPR005333Transcription factor, TCP
PROSITE profilePS5136927.92379133IPR017887Transcription factor TCP subgroup
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008283Biological Processcell proliferation
GO:0009735Biological Processresponse to cytokinin
GO:0009737Biological Processresponse to abscisic acid
GO:0009739Biological Processresponse to gibberellin
GO:0010029Biological Processregulation of seed germination
GO:0010229Biological Processinflorescence development
GO:0031347Biological Processregulation of defense response
GO:0005634Cellular Componentnucleus
Sequence ? help Back to Top
Protein Sequence    Length: 391 aa     Download sequence    Send to blast
MDGAGSSDDH QLHHRHNFPF QLLEKKEDEQ PCSSSSAYPS LPTAITTTDQ NTPSSNRSIS  60
TLQISPEPSK KPPPKRTSTK DRHTKVDGRG RRIRMPALCA ARVFQLTREL GHKSDGETIE  120
WLLQQAEPAV IAATGTGTIP ANFTSLNISL RSSGSSMSVP SQLRSVNYNS NFSMQQRRSL  180
FPGIGLDNAT PTFLNFQSSN LNAMLQAKQE YRDNNNSLEL SAETEESLGR KRRPEQDLSS  240
QHQMGNYLMQ SSTGAIPASH SHSHGHVHGQ IPANFWMVTN SNNPVMSGDP VWTFPSVNNS  300
AALYRGTMSS GLHFMNFSTP LALLPSQQLG SSISSGGGGS SGMNEGQLNM LAGLNPYRPV  360
TGTGVSESQA SGSHSHHGGG DDRHDTTSHH S
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved the regulation of plant development. Together with TCP15, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in leaf and floral tissues (PubMed:21668538). Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1 (PubMed:25655823). Involved in the regulation of seed germination. May regulate the activation of embryonic growth potential during seed germination (PubMed:17953649, PubMed:22155632). Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers (PubMed:22267487). Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3 (PubMed:25757472). Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity (PubMed:24689742). Involved in positive regulation of plant defense. Represses jasmonate (JA) response to promote disease resistance. Regulates the plant immune system by transcriptionally repressing a subset of JA-responsive genes (PubMed:28132837). {ECO:0000269|PubMed:17953649, ECO:0000269|PubMed:21668538, ECO:0000269|PubMed:22155632, ECO:0000269|PubMed:22267487, ECO:0000269|PubMed:24689742, ECO:0000269|PubMed:25655823, ECO:0000269|PubMed:25757472, ECO:0000269|PubMed:28132837}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00396DAPTransfer from AT3G47620Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced during seed imbibition (PubMed:17953649). Circadian-regulation with the lowest expression in the middle of the dark period (PubMed:17953649). {ECO:0000269|PubMed:17953649}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKU9475014e-83KU947501.1 Toxicodendron vernicifluum microsatellite c14890(AGT)6 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018826533.11e-180PREDICTED: transcription factor TCP14
SwissprotQ93Z002e-68TCP14_ARATH; Transcription factor TCP14
TrEMBLA0A2P5RU471e-179A0A2P5RU47_GOSBA; Uncharacterized protein
STRINGVIT_17s0000g06020.t011e-177(Vitis vinifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM39152757
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G47620.11e-53TEOSINTE BRANCHED, cycloidea and PCF (TCP) 14
Publications ? help Back to Top
  1. Steiner E, et al.
    The Putative O-Linked N-Acetylglucosamine Transferase SPINDLY Inhibits Class I TCP Proteolysis to Promote Sensitivity to Cytokinin.
    Plant Physiol., 2016. 171(2): p. 1485-94
    [PMID:27208284]
  2. Yang L, et al.
    Pseudomonas syringae Type III Effector HopBB1 Promotes Host Transcriptional Repressor Degradation to Regulate Phytohormone Responses and Virulence.
    Cell Host Microbe, 2017. 21(2): p. 156-168
    [PMID:28132837]
  3. Zhang N, et al.
    MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis.
    Plant J., 2018. 93(1): p. 66-78
    [PMID:29086441]
  4. Mazur MJ, et al.
    Arabidopsis TCP Transcription Factors Interact with the SUMO Conjugating Machinery in Nuclear Foci.
    Front Plant Sci, 2017. 8: p. 2043
    [PMID:29250092]