PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Neem_6347_f_3 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
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Family | C2H2 | ||||||||
Protein Properties | Length: 467aa MW: 50791.4 Da PI: 9.2247 | ||||||||
Description | C2H2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | zf-C2H2 | 15.7 | 4.2e-05 | 64 | 84 | 3 | 23 |
ETTTTEEESSHHHHHHHHHHT CS zf-C2H2 3 CpdCgksFsrksnLkrHirtH 23 C++Cgk F r nL+ H r H Neem_6347_f_3 64 CEICGKGFQRDQNLQLHRRGH 84 *******************88 PP | |||||||
2 | zf-C2H2 | 13.5 | 0.00021 | 138 | 160 | 1 | 23 |
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k++ +s+ k H +t+ Neem_6347_f_3 138 WKCEKCSKRYAVQSDWKAHSKTC 160 58*****************9998 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:3.30.160.60 | 4.0E-5 | 61 | 84 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SuperFamily | SSF57667 | 2.97E-6 | 61 | 84 | No hit | No description |
PROSITE profile | PS50157 | 11.489 | 62 | 84 | IPR007087 | Zinc finger, C2H2 |
SMART | SM00355 | 0.076 | 62 | 84 | IPR015880 | Zinc finger, C2H2-like |
PROSITE pattern | PS00028 | 0 | 64 | 84 | IPR007087 | Zinc finger, C2H2 |
Gene3D | G3DSA:3.30.160.60 | 1.5E-4 | 126 | 159 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SuperFamily | SSF57667 | 2.97E-6 | 133 | 158 | No hit | No description |
SMART | SM00355 | 130 | 138 | 158 | IPR015880 | Zinc finger, C2H2-like |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0044212 | Molecular Function | transcription regulatory region DNA binding | ||||
GO:0046872 | Molecular Function | metal ion binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 467 aa Download sequence Send to blast |
MAEETIPNGF VQNSAAGSNP PAVKKKRNLP GTPGKQLLYS IIDPEAEVIA LSPKTLMATN 60 RFLCEICGKG FQRDQNLQLH RRGHNLPWKL KQRASKEVRK RVYVCPEKTC VHHHPSRALG 120 DLTGIKKHFC RKHGEKKWKC EKCSKRYAVQ SDWKAHSKTC GTREYKCDCG TIFSRRDSFI 180 THRAFCDALA EETARVNAAS SMNSLANGTI NYHLMGTPLG PSVAQHFSSI FKPISSSAET 240 IDQTRRGLSI WMAPASQGHE NIVNNLQEIH QVGSMHSGTA VFGDPLASCS NPPPSDDHLN 300 WVFGNKLSSN NAHEALASTS LPLTDVKEAA THQLVSVPSL YSSQQHTHQA ASADMSATAL 360 LQKAAQIGAT STHPSFLGSF GLKCSSNQVQ DGNKFCGLYG STAIANNLGT DVEKSGSDIS 420 TLSQPQMPPA KRRHLLSEES TGGQTRDFLG VGVQAISCHP SSIRGWI |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
5b3h_C | 2e-36 | 134 | 203 | 3 | 72 | Zinc finger protein JACKDAW |
5b3h_F | 2e-36 | 134 | 203 | 3 | 72 | Zinc finger protein JACKDAW |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00125 | DAP | Transfer from AT1G03840 | Download |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_007043706.2 | 0.0 | PREDICTED: zinc finger protein MAGPIE isoform X2 | ||||
Swissprot | Q9ZWA6 | 1e-150 | IDD3_ARATH; Zinc finger protein MAGPIE | ||||
TrEMBL | A0A061E4I0 | 0.0 | A0A061E4I0_THECC; C2H2 and C2HC zinc fingers superfamily protein | ||||
STRING | EOX99537 | 0.0 | (Theobroma cacao) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM3710 | 26 | 60 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G03840.1 | 1e-153 | C2H2 family protein |
Publications ? help Back to Top | |||
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