PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_5887_f_1

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

MYB

Protein Properties

Length: 318aa MW: 34340.4 Da PI: 8.3941

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_5887_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	59.6	6.8e-19	12	57	1	47
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 +g+W++eEde l +v+++G+++W++I++ ++ gR++k+c++rw + Neem_5887_f_1 12 KGPWSPEEDEALQLLVQKHGPRNWSLISKSIP-GRSGKSCRLRWCNQ 57 79****************************.*********985 PP
2	Myb_DNA-binding	56.9	4.7e-18	66	108	3	47
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 ++T+eEde +++a++++G++ W+tIar ++ gRt++ +k++w++ Neem_5887_f_1 66 AFTPEEDEMIIRAHARFGNK-WATIARLLN-GRTDNAIKNHWNST 108 79****************.*****.*********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	25.466	7	62	IPR017930	Myb domain
SuperFamily	SSF46689	1.08E-32	9	105	IPR009057	Homeodomain-like
SMART	SM00717	6.3E-17	11	60	IPR001005	SANT/Myb domain
Pfam	PF00249	1.6E-18	12	57	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	5.1E-26	13	65	IPR009057	Homeodomain-like
CDD	cd00167	2.93E-16	14	56	No hit	No description
SMART	SM00717	1.8E-15	63	111	IPR001005	SANT/Myb domain
PROSITE profile	PS51294	21.605	64	113	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	8.0E-24	66	112	IPR009057	Homeodomain-like
Pfam	PF00249	1.8E-15	66	108	IPR001005	SANT/Myb domain
CDD	cd00167	7.49E-13	66	109	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009723	Biological Process	response to ethylene
GO:0009737	Biological Process	response to abscisic acid
GO:0009751	Biological Process	response to salicylic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0010200	Biological Process	response to chitin
GO:0046686	Biological Process	response to cadmium ion
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 318 aa Download sequence Send to blast
MAFNRKEVDR IKGPWSPEED EALQLLVQKH GPRNWSLISK SIPGRSGKSC RLRWCNQLSP 60 QVEHRAFTPE EDEMIIRAHA RFGNKWATIA RLLNGRTDNA IKNHWNSTLK RKCSSLMTGN 120 GNFGNCNGYD GDFGENCQQQ PLKRSVSAGS GLPVTTGLYM NPGSPSGSDV SDSSVPGLSS 180 NYNIFKPVAR TGGINVDVNM VPETTSSSND PPTSLSLSLP GADSPEVSNK VSEPAQAVNA 240 KPSLGGPVSC CREERSSDSG SKGFVGFSSE FMAVMQEMIR QEVRTYMAAL EQQRGGACYQ 300 GGGSGDGVFR NVAMQRIG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1mse_C	6e-42	11	112	3	104	C-Myb DNA-Binding Domain
1msf_C	6e-42	11	112	3	104	C-Myb DNA-Binding Domain
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that functions in salt stress response. Acts as negative regulator of NHX7/SOS1 and CBL4/SOS3 induction in response to salt stress (PubMed:23809151). In response to auxin, activates the transcription of the auxin-responsive gene IAA19. The IAA19 transcription activation by MYB73 is enhanced by direct interaction between MYB73 and PYL8 (PubMed:24894996). {ECO:0000269\|PubMed:23809151, ECO:0000269\|PubMed:24894996}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00476	DAP	Transfer from AT4G37260	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by salt stress. {ECO:0000269\|PubMed:23809151}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006425988.1	0.0	transcription factor MYB44
Swissprot	O23160	1e-108	MYB73_ARATH; Transcription factor MYB73
TrEMBL	A5HLW5	0.0	A5HLW5_CITSI; Putative R2R3-Myb transcription factor
TrEMBL	V4RWL5	0.0	V4RWL5_9ROSI; Uncharacterized protein
STRING	XP_006425988.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM677	28	135

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37260.1	1e-100	myb domain protein 73

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]